Basal Cell Carcinoma

Question 1

Basal Cell Carcinoma

caused by?

Answer 1

exposure to UV radiation induced DNA damage

Question 2

Basal Cell Carcinoma

risk factors

Answer 2

1. Fitzpatrick skin types 1-2
2. severe actinic damage
3. males > females
4. immunosuppression

Question 3

Basal Cell Carcinoma

has it is usually metastasized?

Answer 3

no- usually local

Question 4

Basal Cell Carcinoma

Clinical Manifestations w/ Nodular BCC

Answer 4

1. raised, dome-shaped, papules w/ “rolled” borders & central depression/ulceration wtih underlying telagectasias
2. pink/white/flesh colored
3. translucent, waxy, pearly quality

Question 5

Basal Cell Carcinoma

Clinical Manifestations w/ superficial BCC

Answer 5

1. slightly scaly, eczematous-like, macules, patches, or thin plaques
2. characteristic raised, pearly, white, rolled border
3. pink to light red

Question 6

Basal Cell Carcinoma

Tx- surgical

Answer 6

• electrodessication and curettage
• excision
• MOHS

Question 7

Basal Cell Carcinoma

Tx- nonsurgical

who gets this?

Answer 7

reserved for superficial BCC or poor surgical candidates

Question 8

Basal Cell Carcinoma

Tx- nonsurgical

Answer 8

1. imiquimod 5% cream: weeknight application x6 wks
2. Fluorouracil 5% cream BID, x12 wks
3. Radiation