Basic Concepts Flashcards
(13 cards)
The adaptive differs from the innate immune system by being very
Specific
What mediates the connection between the innate and acquired immune response?
Messenger molecules known as CYTOKINES
Antigen receptors bind to ..
Epitopes (small areas of the surface of the antigen)
What is an epitope?
A small area of the molecular structures of the antigen, that the antigen receptors bind to
Give two examples of antigen receptors
Antibodies (B cell antigen receptors& ones in blood)
T cell antigen receptors
B and T cell antigen receptors are distributed how?
Clonally. Antigen encounters B cell with appropriate antibody to bind to it, the B cell divides.
When B cell matures into a plasma cell it secretes the specific immunoglobulin (antibodies) for the antigen
Vaccinations work via what principle?
Memory of immune system
Response is faster and greater in magnitude if you re-encounter an antigen.
Compare the innate and adaptive immune system characteristics
Innate
- non-specific response
- fast response (mins)
- no memory
Adaptive
- very specific
- slow response (days)
- Memory
IgD is a
B cell receptor
IgG is a
Virus neutraliser
IgE triggers
Allergic response
IgM is important in
Opsonisation
IgA is found in
Secretions. protected against prototypic attack by secretory component