Flashcards in basic science Deck (61)
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1
Stratum Spinosum __made de novo
– K1 and 10
3
not made de novo in Stratum Spinosum
– K5 and 14
3
K1 and 10 downregulated in
psoriasis
4
– K6 and 16 upregulated in
psoriasis
5
Desmocollin (Dsc) 1 (115kd and 105kd) and 2
Subcorneal pustular derm
7
LABD Ag (NC 16 and col) (97/120kd)
Linear IgA
8
Desmoglein (Dsg) 3 (130kd)
ntraepidermal neutrophilic
IgA dermatosis
8
JEB
lam 5
9
Intergrin a6b4
JEB with pyloric atresia
10
Dsg 3 mostly, Dsg 1
Pemphigus vulgaris
11
Pemphigus foliaceus
Dsg 1 (160kd)
12
BPAg1 (230kd), Plectin
Desmoplakin (250kd),Envoplakin (210kd), Periplakin (190kd),(500kd), Dsg 1 and 3
Paraneoplastic Pemphigus
13
cells that arrive first
• Neutrophils (greater in number) and monocytes
14
Wound Healing
• Platelets (first response) release mediators like
ADP
15
• Granulation
Fibronectin -->col III →
col I
16
– 4 days after injury
• Granulation
17
• Wound contraction
– are important (contain actin)
Myofibroblasts
18
– Hours after injury
• Epithelialization
19
___ are required for healing perform
– Debridement and secretion
• Macrophages
20
k ___in all layers of migrating epidermis (normally in basal only)
– K5 and 14
– K6 and 16
21
col V, fibrin and fibronectin form
provisional matrix
22
___ receptors guide the path
– Integrin
23
• First follicles on face at gestation
nine weeks
24
• Hair-Remaining develop at
four to five months
25
• Adults cannot generate new follicles T/F
T
26
Most mitotic activity below this line
– Critical line of Auber
• Widest diameter of the bulb
27
maintains the integrity of hair
– Cuticle
28
bulk of keratins
– Cortex contains
29
broken during hair styling
– Disulfide bonds are
30
