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Flashcards in basic science Deck (61)
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1

Stratum Spinosum __made de novo

– K1 and 10

3

not made de novo in Stratum Spinosum

– K5 and 14

3

K1 and 10 downregulated in

psoriasis

4

– K6 and 16 upregulated in

psoriasis

5

Desmocollin (Dsc) 1 (115kd and 105kd) and 2

Subcorneal pustular derm

7

LABD Ag (NC 16 and col) (97/120kd)

Linear IgA

8

Desmoglein (Dsg) 3 (130kd)

ntraepidermal neutrophilic
IgA dermatosis

8

JEB

lam 5

9

Intergrin a6b4


JEB with pyloric atresia

10

Dsg 3 mostly, Dsg 1

Pemphigus vulgaris

11

Pemphigus foliaceus

Dsg 1 (160kd)

12

BPAg1 (230kd), Plectin
Desmoplakin (250kd),Envoplakin (210kd), Periplakin (190kd),(500kd), Dsg 1 and 3


Paraneoplastic Pemphigus

13

cells that arrive first

• Neutrophils (greater in number) and monocytes

14

Wound Healing
• Platelets (first response) release mediators like

ADP

15

• Granulation
Fibronectin -->col III →

col I

16

– 4 days after injury

• Granulation

17

• Wound contraction
– are important (contain actin)

Myofibroblasts

18

– Hours after injury

• Epithelialization

19

___ are required for healing perform
– Debridement and secretion

• Macrophages

20

k ___in all layers of migrating epidermis (normally in basal only)

– K5 and 14
– K6 and 16

21

col V, fibrin and fibronectin form

provisional matrix

22

___ receptors guide the path

– Integrin

23

• First follicles on face at gestation

nine weeks

24

• Hair-Remaining develop at

four to five months

25

• Adults cannot generate new follicles T/F

T

26

Most mitotic activity below this line

– Critical line of Auber
• Widest diameter of the bulb

27

maintains the integrity of hair

– Cuticle

28

bulk of keratins


– Cortex contains

29

broken during hair styling


– Disulfide bonds are

30

– Outer root sheath (ORS)
followed by


(IRS) then shaft