Basics Flashcards by Jeff Stanton

Flashcards in Basics Deck (14)

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Define sensitivity

The ability to identify positive results
The ability to detect small amounts of analyte
Proportion of people that have the disease that will test positive

Calculate sensitivity

Sensitivity = (TP/TP + FN) X 100

Define specificity

The ability to identify negative results
The selectivity of an assay reaction
Proportion of people known not to have a dz that will test negative for it

Calculate specificity

Specificity = (TN/TN + FP) X 100

Define Type I error (α)

false positive rate

Calculate Type I error (α)

1 – specificity

Define Type II error (β)

false negative rate

Calculate Type II error (β)

1- sensitivity

Define PPV

Proportion of positive test results that are true positives (correct diagnoses)

Calculate PPV

Positive Predictive Value (Precision Rate) = TP/TP + FP (total positive calls)

Define NPV

Proportion of negative test results that are true negatives (correct diagnoses)

Calculate NPV

Negative Predictive Value = TN/TN + FN (total negative calls)

As the prevalence of a condition increases, does the sample size required to detect the condition increase or decrease?

Decrease

Does the number of animals that must be sample in order to achieve a certain level of confidence increase or decrease as the colony size decreases?

Increase (BB pg 383)

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Statistics > Basics > Flashcards

Define sensitivity

The ability to identify positive results
The ability to detect small amounts of analyte
Proportion of people that have the disease that will test positive

Calculate sensitivity

Sensitivity = (TP/TP + FN) X 100

Define specificity

The ability to identify negative results
The selectivity of an assay reaction
Proportion of people known not to have a dz that will test negative for it

Calculate specificity

Specificity = (TN/TN + FP) X 100

Define Type I error (α)

false positive rate

Calculate Type I error (α)

1 – specificity

Define Type II error (β)

false negative rate

Calculate Type II error (β)

1- sensitivity

Define PPV

Proportion of positive test results that are true positives (correct diagnoses)

Calculate PPV

Positive Predictive Value (Precision Rate) = TP/TP + FP (total positive calls)

Define NPV

Proportion of negative test results that are true negatives (correct diagnoses)

Calculate NPV

Negative Predictive Value = TN/TN + FN (total negative calls)

As the prevalence of a condition increases, does the sample size required to detect the condition increase or decrease?

Decrease

Does the number of animals that must be sample in order to achieve a certain level of confidence increase or decrease as the colony size decreases?

Increase (BB pg 383)

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Basics Flashcards Preview

Statistics > Basics > Flashcards

Define sensitivity

The ability to identify positive resultsThe ability to detect small amounts of analyteProportion of people that have the disease that will test positive

Calculate sensitivity

Sensitivity = (TP/TP + FN) X 100

Define specificity

The ability to identify negative resultsThe selectivity of an assay reactionProportion of people known not to have a dz that will test negative for it

Calculate specificity

Specificity = (TN/TN + FP) X 100

Define Type I error (α)

false positive rate

Calculate Type I error (α)

1 – specificity

Define Type II error (β)

false negative rate

Calculate Type II error (β)

1- sensitivity

Define PPV

Proportion of positive test results that are true positives (correct diagnoses)

Calculate PPV

Positive Predictive Value (Precision Rate) = TP/TP + FP (total positive calls)

Define NPV

Proportion of negative test results that are true negatives (correct diagnoses)

Calculate NPV

Negative Predictive Value = TN/TN + FN (total negative calls)

As the prevalence of a condition increases, does the sample size required to detect the condition increase or decrease?

Decrease

Does the number of animals that must be sample in order to achieve a certain level of confidence increase or decrease as the colony size decreases?

Increase (BB pg 383)

Key Links

Subjects

Company

Find Us

Brainscape's Knowledge Genome^TM

The ability to identify positive results
The ability to detect small amounts of analyte
Proportion of people that have the disease that will test positive

The ability to identify negative results
The selectivity of an assay reaction
Proportion of people known not to have a dz that will test negative for it