bbb Flashcards

1
Q

define transfusion associated graft versus host disease

what is the reaction?

A

due to proliferation of competent lymphocytes in which the donor’s lymphocytes attacktes the transfusion recipient.

maculopapular rash starts at the center then to the extremitiies

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2
Q

define febrile non-hemolytic transfusion reaction

A

it is the most commonly encountered in which the reaction is caused by the donor HLA antigen present in wbc and platelets attacked by recipient’s antibodies.

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3
Q

what is the most dangerous blood type? why?

what is the testing?

A

ABO due to IgM and complement activation

DAT positive

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4
Q

define iatrogenic

A

Iatrogenic is caused by the physician in which it happens in the transfusion associated circulatory overload due to phyisician’s fault not the blood components itself.

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5
Q

treatment for PTP

A

infuse intravenous immunoglobulin

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6
Q

what to check for bacterial contamination?

A
  • cloudiness
  • color change
  • clots
  • hemolysis

you may perform gram stain and culture

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7
Q

viability of FFP

for emergency blood transfusion

A

group O RBCs
blood type O

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8
Q

2nd most common transfusion reaction

A

allergic transfusion reaction

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9
Q

types of blood donors

A
  • autologous
  • allogenous
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10
Q

viability of FFP and why?

A

20 minutes
to avoid loss of clotting factors

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