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Med Neuro Block 1 > BBB > Flashcards

Flashcards in BBB Deck (7):
1

What is the function of the BBB?

helps maintain a stable microenvironment for the proper functioning of neurons within the central nervous system

2

What cells regulate the BBB?

astrocytes

3

What is the BBB?

barrier between the circulation and the interstitial fluid
physical, transport and metabolic barrier

4

How do substances move across the BBB?

transport proteins
receptor-mediated transcytosis
adsorptive transcytosis
paracellular aqueous pathway
transcellular lipophillic pathway

5

L-DOPA

drug used to treat Parkinson's disease

6

Route by which most CNS drugs enter the brain

transcellular lipophillic pathway

7

Areas of the brain that lack the blood brain barrier

Area postrema
choroid plexus of the 3rd and 4th ventricles
pineal gland
subformical organ
vascular organ of the lamina terminalis