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VT 251 Pharmacology > Behavioral Drugs > Flashcards

Behavioral Drugs Flashcards

1
Q

Most behavioral drugs used in vet med are?

A

Human psychiatric drugs that are used off label/extra label

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2
Q

All psychotherapy drugs are through to produce their effects by?

A

Altering neurotransmitter activity in the brain

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3
Q

What neurotransmitter are effected by psychotherapy drugs?

A
  1. Acetylcholine
  2. Dopamine
  3. Norepinephrine (Noradrenaline)
  4. Serotonin
  5. GABA: Gamma-Aminobutyric Acid
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4
Q

We are 100% sure how psychotherapy drugs work in animals

A

False - we do not know for 100$ sure

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5
Q

What are common anti-anxiety medications used in vet meds?

A
  1. Benzodiazepines
  2. Buspirone
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6
Q

What are common Benzodiazepines used in vet med for anxiety relief?

A
  1. Alprazolam (Xanax)
  2. Diazepam
  3. Lorazepam
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7
Q

Benzodiazepines clinical use?

A
  1. Fears
  2. Phobias
  3. Urine Marking *Cats
  4. Aggression
  5. Dementia
  6. OCD
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8
Q

Benzodiazepine side affects?

A
  1. Lethargy
  2. Ataxia
  3. Increased Appetite
  4. Hyper-Excitability
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9
Q

Buspirone works by?

A

Thought to block serotonin receptors in the brain *Not 100% sure

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10
Q

Buspirone clinical use?

A
  1. Urine Marking *Cats
  2. Fear Anxiety
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11
Q

Is Buspirone a controlled drug?

A

No

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12
Q

What are common antidepressants used in vet med?

A
  1. Tricyclic Antidepressants
  2. A electric Serotonin Reuptake Inhibitors (SSRI’S)
  3. Tazadone
  4. Monoamine Oxidase Inhibitors
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13
Q

Tricyclic Antidepressants are thought to work by?

A

Preventing the re-uptake of norepinephrine & serotonin

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14
Q

Tricyclic antidepressants clinical use?

A
  1. Separation anxiety
  2. Obsessive compulsive disorders
  3. Aggression
  4. Urine Marking
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15
Q

Common Tricyclic antidepressants used in vet meds?

A
  1. Clomipramine
  2. Amitriptyline
  3. Imipramine
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16
Q

Tricyclic antidepressant adverse effects?

A
  1. Sedation
  2. Anticholinergics Effects
    - Dry Mouth
    - Tachycardia
    - Mydriasis
    - Decreased Tear Production
    - Constipation
17
Q

Selective-Serontonin Reuptake Inhibitors (SSRI’S) commonly used in vet med?

A
  1. Fluoxetine (Prozac)
  2. Sertraline (Prozac)
  3. Paroexetine (Paxil)
18
Q

Selective serotonin reuptake inhibitors work by?

A

Increasing the amount of serotonin in the neural synapse by preventing its reuptake into the nerve terminal which increases the amount of serotonin in the neural synapse/brain

19
Q

Selective Serotonin Reuptake Inhibitors Clinical Use:

A
  1. OCD
  2. Aggression
  3. Phobias
  4. Separation Anxiety
  5. Urine Marking
20
Q

Selective Serotonin Reuptake Inhibitors Adverse Affects

A
  • Lethargy
  • Anorexia
  • Nausea
  • Diarrhea
  • Anxiety
  • Restless
21
Q

Trazodone is said to work by?

A
  • Blocking serotonin receptors & preventing serotonin reputable in the synapse.
  • Considered serotonin antagonist & reuptake inhibitors
22
Q

Trazadone can be prescribed w/

A

Gabapenting for dogs to help with/ sedation

23
Q

Trazodone is not commonly prescribed in which species?

A

Cats

24
Q

Trazodone clinical use?

A
  • Manage short term anxiety (Calm Anxious Animals)
  • Fireworks
  • Noise Anxiety
25
Q

Trazodone adverse effects?

A
  • Sedation
  • Aggression
  • Nausea
26
Q

Monoamine Oxidase Inhibitors is said to work?

A

By inhibiting the enzyme that breaks down dopamine allowing dopamine levels to increase in the brain.
* It is said that older dogs produce less dopamine in their body which is why its common for older dogs to get dementia

27
Q

Monoamine Oxidase Inhibitors used in vet med?

A

Selegiline

28
Q

Monoamine Oxidase Inhibitors clinical use?

A

Dementia : Canine Cognitive Dysfunction Syndrome
*Old Dog Dementia

29
Q

Monoamine Oxidase Inhibitors Adverse Effects

A
  • Vomiting
  • Diarrhea
  • Anorexia
  • Salivation
  • Restlessness
30
Q

Explain serotonin syndrome

A

Concurrent use of multiple antidepressants can cause:
- diarrhea
- Vomiting
- Tachycardia
- Muscle Tremors / Muscle Stiffness
- Restlessness
- Panting
- Disorientation
- Seizures

VT 251 Pharmacology (15 decks)

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