Behavioural Pharmacology Flashcards Preview

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Flashcards in Behavioural Pharmacology Deck (12):
1

What can you use to treat urinary incontinence in a bitch, where all behavioural causes have been excluded?

Phenylpropanolamine (Propalin) - sympathomimetic agent
Increases urethral tone

2

Which tricyclic anti-depressant is licensed for separation anxiety in dogs?

Clomipramine (Clomicalm)

3

Which oral benzodiazepines are available for use in dogs at home? Eg: bonfire night

Diazepam (Valium) - 4-6 hours duration
Alprazolam (Xanax) - 6-8 hours duration

4

Which benzodiazepine is injectable, so can be integrated into a sedation / premedication protocol?

Midazolam (Hypnovel)

5

What are the effects of benzodiazepines?

Amnesia up to one hour after event
Anxiolytic
Disinhibition - dogs often switch from inhibition to repulsion

6

What can be prescribed for motion sickness in dogs?

Maropitant (Cerenia) - centrally acting antiemetic
Neurokinin 1 antagonist

7

What drug can be used in cases of separation anxiety, compulsive disorders and aggression in dogs?

Fluoxetine (Prozac)
Decreases anxiety, increases threshold for behavioural reactivity

8

Name 2 partial benzodiazepines, these are only licensed for sound phobias.

Imepitoin (Pexion)
Micro-dose of Dexmedetomidine (Sileo)

9

What monoamine oxidase inhibitor is licensed for the treatment of sound phobias, generalised phobia and anxiety?

Selegiline (Selgian)

10

What drug can be used in a emergency to calm separation anxiety?

Benzodiazepines - diazepam, alprazolam

11

What pharmacological agents are indicated in the management of canine cognitive dysfunction?

Selegiline
Propentofyline (Vivitonin) - improves astrocyte health

12

What neutraceuticals are indicated in the management of canine cognitive dysfunction?

Medium chain triglycerides - metabolised to ketone bodies, the preferential energy source of neurones in CCD
Vitamin A and E - antioxidants slow plaque progression