behcet's disease

Question 1

what is behcet’s disease

Answer 1

rare multiorgan disease caused by systemic vasculitis of veins and arteries of all sizes, hypercoagulability and neutrophil hyperfunction.

Question 2

signs of behcet’s

Answer 2

oral and genital ulcers, uveitis, erythema nodosum, vasculitis, acneiform lesions, thrombophlebitis at venepuncture sites, pathergy, arthralgias

Question 3

investigations of behcet’s

Answer 3

blood tests to look for: RF, ANA, ANCA, ACE levels, HLAB51 and pathergy test

Question 4

imaging for behcet’s

Answer 4

CNS imaging and lumbar puncture, Endoscopy, HRCT, ophthamology review, biopsy for vasculitis

Question 5

treatment of behcet’s

Answer 5

Steroids, colchicine, azathioprine, methotrexate, DMARDs