Benign Pathology and Breast Changes Flashcards
(27 cards)
Most common diffuse breast disorder?
Fibrocystic change
Exaggeration of normal proliferative and involutional changes. Likely related to a predominance of estrogen and progesterone is what?
Fibrocystic change
Clinical features of fibrocystic change?
- Women 35-55
- breast pain
- multiple breast lumps
- varies with menstrual cycle
- occasional nipple discharge
- regress after menopause
What is the result of an obstruction of the extralobular duct by epithelial proliferation or fibrosis?
Simple cyst
A milk filled retention cyst associated with lactation?
Galactocele
During lactation, bacteria can enter through a crack in the nipple which allows bacteria to enter a breast duct and occlude the duct orifice. What is this called?
Puerperal (lactational mastitis)
What is referred to as plasma cell mastitis, chronic mastitis or mammary duct ectasia depending on the stage or histologic findings present?
Periductal Ectasia
What type of mastitis typically effects peri and postmenopausal women?
periductal mastitis
Descriptive term that can be associated with a variety of conditions. Silicone is a common cause for this?
Granulomatous Mastitis
Thrombophlebitis of the superficial veins of the anterior breast and chest is what?
Monder’s disease
Localized trauma to breast can cause focal hemorrhage and liquefaction of breast fat leading to what?
Fat necrosis
Most common benign solid tumor?
Fibroadenoma
Overgrowth of connective and glandular tissue within a lobule that is an estrogen induced breast tumor?
Fibroadenoma
Variants of fibroadenoma?
Complex fibroadenoma and juvenile fibroadenoma
Rapidly growing mass during pregnancy and lactation in response to hormones?
Lactating (secretory) adenoma
What grows within a major lactiferous duct near areola, not in TDLU?
Intraductal papilloma
Most common cause of spontaneous bloody nipple discharge?
Intraductal papilloma
What features of a papillary lesion are more suspicious for cancer?
> 1.5 cm with in duct, expands duct, or extends into branching ducts.
What carries a higher risk for cancer than a solitary, central, large duct papilloma?
Multiple peripheral papillomatosis
Adolescent women with multiple small cysts in a Swiss-cheese appearance. Up to 28% of patients have positive family history of breast cancer?
Juvenile papillomatosis
An overgrowth of adipose tissue encased by a thin connective tissue capsule?
lipoma
Uncommon, localized overgrowth of fibrous, epithelial, or adipose tissues that lacks a true capsule?
Hamartoma
Focal accumulation of dense stroll fibrous tissue. TDLU’s are atrophic, obliterated, or underdeveloped?
Focal fibrosis
Disorders in collagen metabolism area feature of diabetes?
Diabetic mastopathy
