Beta Lactam ABs Flashcards

(46 cards)

1
Q

Penicillins: different group names

A

Narrow spectrum
Penicillinase-stable
Broad spectrum
Against Pseudomonas

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2
Q

Beta-Lactamase Inhibitors

A

Clavulanic acid
Sulbactam
Tazobactam

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3
Q

Cephalosporins: how many generations

A

Generations 1-4

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4
Q

Carbapenems

A

Imipenem

Meropenem

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5
Q

Monobactams

A

Aztreonam

Tigemonam

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6
Q

What is special about Gen 3 and 4 Cephalosporins?

A

CIA

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7
Q

What is the mode of action of Beta-lactam AB?

A

Time-dependent bactericidal

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8
Q

What is the mechanism of action of Beta-lactam AB?

A

Inhibition of cell wall synthesis

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9
Q

What is the mode of action of Penicillins?

A

Time-dependent bactericidal

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10
Q

What is the mode of action of Cephalosporins?

A

Time-dependent bactericidal

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11
Q

What is the mode of action of Carbapenems?

A

Time-dependent bactericidal

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12
Q

What is the mode of action of Monobactams?

A

Time-dependent bactericidal

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13
Q

What is the mechanism of action of Penicillins?

A

Inhibition of cell wall synthesis

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14
Q

What is the mechanism of action of Cephalosporins?

A

Inhibition of cell wall synthesis

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15
Q

What is the mechanism of action of Monobactams?

A

Inhibition of cell wall synthesis

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16
Q

What is the mechanism of action of Carbapenems?

A

Inhibition of cell wall synthesis

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17
Q

Name the Narrow spectrum penicillins

A

Benzylpenicillin-Na, K
Benzylpenicillin-Procaine
Benzylpenicillin-benzathine
Phenoxymethy-penicillin

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18
Q

Name the penicillinase stable penicillins

A

Oxacillin
Cloxacillin
Dicloxacillin
Flucloxacillin

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19
Q

Name the broad spectrum penicillins

A

Amoxicillin

Ampicillin

20
Q

Name the penicillins against Pseudomonas

A

Ticarcillin

Piperacillin

21
Q

1st Generation Cephalosporins

A

Cephazoline
Cephapirin
Cefadroxil
Cephalexin

22
Q

2nd Generation Cephalosporins

23
Q

3rd Generation Cephalosporins

A
Ceftiofur
Cefovecin
Ceftriaxone
Cefotaxime
Ceftazidime
Cefoperazone
24
Q

4th Generation Cephalosporins

25
Amoxicillin-Clavulanic acid administration route in swine?
PO
26
Cefquinome administration route in swine?
IM
27
Ceftiofur administration route in swine?
IM
28
Cefadroxil belongs to which group?
Generation I. Cephalosporin
29
``` Which of the following combo would you recommend in pneumonia in dogs? A) AmoxiClav + Enrofloxacin B) AmoxiClav + Cefuroxime C) Both of them D) None of them ```
C) Both of them
30
AmoxiClav belongs to which AMEG group?
AMEG C
31
Which bacteria CANNOT produce beta lactase enzyme?
Streptococcus suis
32
Which drug is NOT authorised for poultry in the EU?
AmoxiClav
33
What is Ceftiofur-HCl turned into?
Desfuroyl-Ceftiofur quickly in the body
34
Which agent would be first line in acute pharyngitis in dogs?
Penicillin
35
Which drug belongs to first line treatment of pyoderma in dogs?
Cefovecin
36
Imipenem belongs to?
Carbapenem
37
Dicloxacillin belongs to?
Penicillinase-resistant penicillins
38
Which generation of cephalosporins does Ceftiofur belong to?
3rd Generation
39
Which AMEG group and generation does Cefquinome belong to?
AMEG B | 4th Generation
40
Which cephalosporin belongs to the first line treatment of pyoderma in dogs?
Cefalexin
41
Cefoperazon belongs to which generation of Cephalosporins?
3rd Generation
42
This drug can effectively be used in cystitis in dogs if its caused by enterococci or lactamase producing E. coli?
Amoxicillin clavulanic acid and Amoxicillin
43
This drug is authorised for poultry and can be effective against fowl cholera?
Amoxicillin
44
This drug is authorised for poultry and can be effective against ulcerative enteritis?
Phenoxymethylpenicillin
45
True or False: | Amoxicillin is authorised only for intramuscular administration in both swine and cattle.
False
46
True or False: In case of bovine P. Multocida respiratory disease the MIC value for ceftiofur is 0.004 mg/𝞵l. The concentration reached in the PELF, in the blood and in the pulmonary interstitial fluid is higher than the MIC value for more than 8 days. This means a correct drug choice for the treatment of the infectious disease.
True