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Antidiabeticos Orales > Biguanidas > Flashcards

Biguanidas Flashcards

1
Q

METFORMINA

Nombre comercial

A

GLUCOFAGE

DIAFORMINA

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2
Q

METFORMINA

Presentacion

A

Glucofage: tabletas de 500mg, 850mg, y 1000mg

Diaformina: comprimidos LP: 850mg, comprimidos 500mg

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3
Q

METFORMINA

Dosificacion

A

Dosis minima: 500mg OD

Dosis maxima: 2500mg/dia

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4
Q

MERFORMINA

vida media

A

1,5 - 3 horas

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5
Q

METFORMINA

Mecanismo de accion

A

Incrementa la actividad de la proteína cinasa dependiente de AMP la cual estimula la captacion periferica de glucosa (musculo y tejido adiposo) y reduce la produccion de glucosa (higado)

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6
Q

METFORMINA

Efectos adversos

A
  • Acidosis lactica
  • hipersensibilidad
  • Disminucion de peso
  • Disminuye absorcion de B12
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7
Q

METFORMINA

Interacciones medicamentosas

A

Potencia el efecto de los anticoagulantes y fibrinoliticos

Furosemida: aumenta la concentracion plasmatica

Ranitidina, Digoxina, morfina: reducen su eliminacion

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Antidiabeticos Orales (6 decks)

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