Insulinas De Accion Prolongada Flashcards

1
Q

GLARGINA:

Nombre comercial

A

Lantus

Opticet

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2
Q

GLARGINA

Presentacion

A

Vial de 10ml (100UI/ml)

Cartuchos de 3 ml

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3
Q

GLARGINA:

Dosificacion

A

Dosis minima: 0,1 UI/jg/dosis

Dosis maxima: 0,5 UI/kg/dosis

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4
Q

GLARGINA:

Vida media

A

24 horas o mas

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5
Q

GLARGINA

Mecanismo de accion

A

Estimulacion de la captacion de periferica de glucosa (especialmente en musculo esqueletico y tejido adiposo)
Su accion prolongada se basa en su distribucion de manera mas lenta por los tejidos

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6
Q

GLARGINA

Efectos adversos

A
  • Hipoglicemia
  • Rash
  • Prurito
  • Disnea
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7
Q

GLARGINA

Interacciones

A

Aumenta efecto: antidiabeticos oralea, IECA, Salicilatos, sulfonamidas, fluoxetina, betabloqueantes.

Disminuye efectos: esteroides, diureticos, glucagon, ACO, estrogenos, progestagenos

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8
Q

DETEMIR

Nombre comercial

A

LEVEMIR

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9
Q

DETEMIR

Presentacion

A

Vial de 10 ml (100 UI/ml)

Cartucho de 3ml

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10
Q

DETEMIR

Dosificacion

A

Dosis minima 0,1 UI/kg/dosis

Dosis maxima: 0,2 UI/kg/dosis

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11
Q

DETEMIR

Vida media

A

8-22 horas

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12
Q

DETEMIR

Mecanismo de accion

A

Estimulacion de la captacion de periferica de glucosa (especialmente en musculo esqueletico y tejido adiposo)
Su accion prolongada se basa en su distribucion de manera mas lenta por los tejidos

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13
Q

DETEMIR

Efectos adversos

A
  • Hipoglicemia
  • Lipodistrofia
  • Hipersensibilidad local y general
  • Hipokaliemia
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14
Q

DETEMIR

Interacciones

A

Aumenta efecto: antidiabeticos oralea, IECA, Salicilatos, sulfonamidas, fluoxetina, betabloqueantes.

Disminuye efectos: esteroides, diureticos, glucagon, ACO, estrogenos, progestagenos

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