Bile Acid Sequestrants Flashcards
1
Q
What is the mechanism of action?
A
They bind and sequester bile acids.
The liver then produces bile acids to replace those that have been lost.
The body uses cholesterol to make bile acids, this reduces the amount of circulating LDL in blood.
2
Q
What are examples?
A
Colesevelam
Colestipol
Colestyramine
3
Q
What are common interactions?
A
It impairs the absorption of fat-soluble vitamins ADEK and other drugs
4
Q
What are counselling points?
A
Take other drugs 1 hour before (4hours for coleveselam) or 4 hours after bile acid sequestrant
