Biliary System Flashcards

1
Q

At what level does the biliary tree begin?

A

Level of the lobules at the bile canailculi

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2
Q

Where are the bile canailculi located?

A

B/w hepatocytes within the interconnecting network

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3
Q

How does the microscopic canailculi form the lobular bile ducts?

A

Anastomose

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4
Q

How are the right and left bile ducts formed?

A

By the union of multiple lobular bile ducts

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5
Q

At what level do the right and left hepatic ducts join to form the CHDs?

A

Porta hepatis

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6
Q

Describe the position of the CHD

A

Anterior to the portal vein

Anterior and lateral to the RHA

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7
Q

Where does the CBD travel?

A

Along the free edge of the lesser omentum

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8
Q

What is the size of the CHD?

A

4mm in diameter

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9
Q

What is the length of the CHD determined by?

A

The insertion point

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10
Q

The CHD joins the cystic duct forming what?

A

CBD

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11
Q

Describe the position of the CBD

A

Anterior and lateral to the MPV

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12
Q

What are the normal diameter ranges for the CBD?

A

Up to 4mm - but varies with age and surgery

Add 1mm for every decade of life after 50years of age

Up to 10mm in post cholecystectomy pt

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13
Q

What ligament does the CBD travel through?

A

Hepatoduodenal ligament

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14
Q

What is the Mickey Mouse appearance?

A

Cross sections through the CBD, HA and MPV

Refer to page 3

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15
Q

How many segments is the CBD divides into?

A

4

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16
Q

What structure are the segments of the CBD relating its position to?

A

Duodenum

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17
Q

What are the 4 segments of the CBD?

A
1st part (supraduodenal)
2nd part (retroduodenal)
3rd part (infraduodenal)
4th part (intraduodenal)
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18
Q

What does the CBD insert into?

A

Ampulla of vater

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19
Q

What regulates the flow of bile?

A

Sphincter of Oddi

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20
Q

What segment is the narrowest part of the extra-hepatic biliary system?

A

4th part

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21
Q

About how many cm does the cystic duct join the hepatic duct above the duodenum?

A

1-2cm

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22
Q

What part of the GB does the cystic duct arise from?

A

Neck

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23
Q

What is the shape and size of the GB?

A

3mm diameter

4cm length

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24
Q

What are the spiral valves of heister? What are there purpose?

A

Mucosal folds- not true valves
Tortuous areas in the cystic duct
Prevents ducts from over distending or collapsing

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25
Q

Where is the GB located?

A

Posterior inferior surface of the right lobe of the liver in the GB fossa

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26
Q

How does the GB lay in relation to the main lobar fissure?

A

Posterior and caudal to the distal end

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27
Q

What parts of the GB are mobile?

A

Fundus and body

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28
Q

How are the fundus and body positioned with the abdomen?

A

Varies with pt position

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29
Q

Is the GB a retroperitoneal or intraperitoneal organ?

A

Intraperitoneal organ

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30
Q

What is the most reliable landmark in identifying the GB?

A

Main lobar fissure

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31
Q

What are some landmarks for identifying the GB?

A

RPV
Duodenum
Right kidney

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32
Q

What is the size and shape of the GB?

A

Varies widely with pt position
Pear or teardrop shape
8-9cm in length
3-5cm in diameter

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33
Q

What are the 3 divisions of the GB? Describe them

A

Fundus- widest portion, projects below inferior liver margin
Body- lies in contact with the visceral surface of the liver
Neck- tapered to spiral valves, fixed

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34
Q

What is the most dependent portion of the GB in the LLD position?

A

Fundus

35
Q

What is another name for the body of the GB?

A

Corpus

36
Q

What is the most dependent portion of the GB in supine?

A

Neck

37
Q

What should the GB measure less then in a fasting state?

A

3mm

38
Q

What are the 4 layers that make up the GB?

A
  1. Mucosa- inner epithelium
  2. Muscular
  3. Subserous- connective tissue
  4. Serous- outer layer in contact with the peritoneum
39
Q

What layer of the GB concentrates bile?

A

Mucosa

40
Q

What are Rokitansky-Aschoff sinuses? (RA sinuses)

A

Multiple folds along the inner border of the GB coated with epithelial cells (not normally seen without pathology)

41
Q

What is the function of the bile ducts?

A

Drain the liver of bile and carry it into the GI system

42
Q

What is the function of the GB?

A

A resivour for bile - stored until required to aid in digestion

43
Q

How much bile can the GB hold?

A

40-70ml

44
Q

How does the GB concentrate the bile?

A

Secrets mucous and absorbs water

45
Q

Where would a stone most likely get stuck within the biliary tree?

A

4th part of the CBD

46
Q

What sort of pattern should the intrahepatic ducts demonstrate?

A

Demonstrate a branching pattern

47
Q

What should the hepatic ducts measure?

A

No more then 2cm in diameter

48
Q

Do we normally see the intrahepatic ducts?

A

Normally no because they are so small but a landmark used is the portal veins

49
Q

How does knowing the position of the GB aid in the diagnosis of gall stones or sludge?

A

Moving the patient into different positions should move the stones with them- if not other pathologies present

50
Q

What controls bile secretion?

A

Hormones

51
Q

With the ingestion of fats and amino acids what does the duodenum release into the blood stream?

A

Cholecystokinin (CCK)

52
Q

What does the release of CCK stimulate?

A

GB contraction and the sphincter of Oddi to relax

53
Q

What does the sphincter of Oddi control?

A

Passage of bile into the duodenum

Prevents reflux of gastrointestinal fluids into the biliary system

54
Q

When does the GB contract following a meal?

A

30min later

55
Q

What happens to the sphincter of Oddi when the GB is removed?

A

Looses it tone and the pressure in the CBD lowers to equal intra-abdominal pressure

56
Q

What happens to the flow of bile if the GB is removed?

A

Bile flows into duodenum during fasting and non-fasting states

Some bile also remains in the ducts

57
Q

How long after the GB has been removed does the sphincter regain tone?

A

6 months

58
Q

What produces bile?

A

Hepatocytes

59
Q

What is the function of bile?

A

Break down fats, helps absorb fatty acids, cholesterol and other lipids from the intestinal tract

60
Q

How much bile salts are produced per day?

A

1 gram

61
Q

What is a precursor to the formation of bile salts?

A

Cholesterol

62
Q

What is jaundice?

A

Yellowish tint due to large quantities of bilirubin

63
Q

What causes jaundice?

A

Hemolytic anemia, acute and chronic hepatic disease, obstructive jaundice, inability of bilirubin in conjugate

64
Q

Where is the arterial blood supply for the GB from?

A

Cystic artery

65
Q

How does the venous drainage of the GB work?

A

Via cystic vein and drains into the portal vein

66
Q

What is a junctional fold?

A

A fold that occurs at the junction of the body and infundibulum (neck)

May look similar to a separation

67
Q

What is a Hartman’s pouch?

A

Outpouching in the area of the GB neck

68
Q

What is a Phrygian cap?

A

When the GB is partially folded on itself in the region of the fundus

69
Q

What are some other variants related to the GB?

A

Septations- thin walls, partial or complete, dividing the GB lumen
Excessively mobile
Ectopic
Low lying the the RLQ
Totally or partially embedded in the liver

70
Q

What is the sonographic appearance of the GB?

A

Anechoic or nearly anechoic

Well defined walls

71
Q

What is the pt prep for the GB?

A

NPO 6-8hours because we want the GB extended to be able to measure the full size and not miss any pathology

72
Q

What is the scanning technique for the GB?

A

2.5-5 MHz probe

Supine, decubitus

73
Q

Why may erect and prone positions be used to examine the GB?

A

Used to rule out stones lodged in the neck and cystic duct

74
Q

What do we examine when imaging the GB?

A

size, shape, content, wall thickeners and area around GB for fluid

75
Q

Why are windows important in examining the GB?

A

To minimize reverberation artifact

76
Q

What are the 3 lab tests used to see if function of GB is distrubted?

A
  1. Bilirubin
  2. Alkaline Phosphatase
  3. Leukocytes
77
Q

What does increased levels of bilirubin INDIRECTLY suggest in the GB?

A

Hemolysis
RBC degradation
Abnormal hepatocellular uptake

78
Q

What does increased levels of bilirubin DIRECTLY suggest in the GB?

A

Extrahepatic obstruction
Bile duct disease
Intrahepatic disruption

79
Q

What does increased levels of alkaline phosphatase in the GB suggest?

A

Extrahepatic biliary obstruction

80
Q

What do leukocytes measure?

A

The reaction of body to infection

81
Q

What do increased levels of leukocytes suggest?

A

Acute and chronic cholecystitis

Injury to bile ducts

82
Q

What are other tests to image and evaluate the GB?

A
  1. HIDA scan

2. ERCP

83
Q

What is a HIDA scan?

A

Nuclear medicine test
Evaluates function of the GB
Radio pharmaceutical injected into patient
Passes through the blood into the liver and then the biliary system