Bilirubin Flashcards
(30 cards)
Which chemical is responsible for the yellow color of the urine?
Urobilin
It is a bile pigment and is the one responsible for the brown color of the stool.
Stercobilin
Which protein transports unconjugated bilirubin to the liver?
Albumin
It is the end product of hemoglobin metabolism.
Bilirubin
In what form is bilirubin excreted into the bile?
Conjugated
What is the normal value of bilirubin for adults?
1.2 mg/dL
It is a condition characterized by the yellowing of the skin and eyes due to high bilirubin levels in the body
Jaundice/Hyperbilirubinemia
The raw material for bilirubin production.
Heme
It is the enzyme responsible for the conversion of B1 to B2.
UDPGT or Uridine Diphosphate Glucoronyl Transferase
Which is the first marker of jaundice/hyperbilirubinemia?
Bilirubin in urine (bilirubinuria)
State two other names for unconjugated bilirubin.
B1, indirect bilirubin, water insoluble, etc.
State two other names for conjugated bilirubin.
B2, direct bilirubin, water soluble, etc.
Pre-hepatic hyperbilirubinemia
Cause:
Bilirubin affected:
Cause: too much RBC destructed
Bilirubin affected: B1
Hepatic hyperbilirubinemia
Cause:
Bilirubin affected:
Cause: liver disease/defect
Bilirubin affected: B1and B2
Post-hepatic hyperbilirubinemia
Cause:
Bilirubin affected:
Cause: physical obstruction
Bilirubin affected: B2
What is the end product of direct bilirubin?
Azobilirubin
Other term for direct bilirubin?
Conjugated bilirubin
What reagent is use for direct bilirubin?
Diazo reagent
What is the reactive component of diazo reagent?
Diazonium salt
This bilirubin method is measured in the absence of an accelerator.
direct bilirubin method
Considered as the most sensitive and most common method used for total bilirubin testing?
Jendrassik-Grof method
The main reagent for the Jendrassik Method?
Diazo reagent
It buffers the pH of the diazotization reaction?
Sodium acetate
Accelerator in Jendrassik-Grof Method?
Caffeine-benzoate
