Bindevævssygdomme Flashcards

0
Q

SLE - symptomer?

A
Diskoid lupus
Sommerfugleeksantem
Fotosensitivitet
Ulcerationer i munden
Serøs pleuritis/pericaditis
Glomerulær nefritis
Træthed, feber, vægttab
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1
Q

SLE - Sygdom

A

Systemisk autoimmun sygdom - især hos kvinder

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2
Q

SLE - blodprøver?

A

MEST: ANA, anti DNA, APLA, RF

Øget celletal, ingen knogleerosioner,

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3
Q

SLE - diff diagnose?

A

RA - da patienter med SLE tidligere i forløbet har en symmetrisk polyartrit der ses på PIP, MCP og håndled.

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4
Q

SLE - behandling?

A

Smerte: NSAID, analgetika
Hud: glukokortikoider, methotrexat

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5
Q

Sjögren - sygdom?

A

Kronisk autoimmun sygdom med infiltration af lymfocytter i eksokrine kirtler og med destruktion af disse tilfølge.

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6
Q

Sjögren - symptomer?

A
Keratoconjunctitis Sicca
Xerostomi
Træthed
muskel og ledsmerter
Glomerulær nefritis
Raynaud
Vasculit
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7
Q

Sjögren - blodprøver?

A

RF, ANA, anti-SSA og anti-SSB

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8
Q

Sjögren - behandling?

A

Spytstimulerende og tårestimulerende

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9
Q

Sjögren - inddeling?

A

Primær: ofte artralgier

Sekundær: RÁ, SLE, sclerodermi

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10
Q

Poly-/dermatomyosit - sygdom

A

Kronisk inflammatorisk myopati i skeletmuskulatur

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11
Q

Poly-/dermatomyosit - symptomer?

A

Svaghed i proximal eksremitet + halsmuskulatur –> fejlsynkning
Ødem ved øjenene

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12
Q

Poly-/dermatomyosit - blodprøver?

A

RF, ANA, muskel enzymer; CK, aldo,

Evt muskelbiopsi

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13
Q

Poly-/dermatomyosit - behandling?

A

Glukokortikoider

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14
Q

Sys.sklerose/sclerodermi - sygdom?

A

Systemiske kronisk bindevævssygdom med fibrose, karforandringer og iskæmisk forandringer.

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15
Q

Sys.sklerose/sclerodermi - inddeling?

A

Diffus og begrænset

16
Q

Sys.sklerose/sclerodermi - symptomer?

A

Raynaud, ødem, sklerose, atrofi

17
Q

Sys.sklerose/sclerodermi - blodprøver?

A

RF, ANA

18
Q

Sys.sklerose/sclerodermi - røntgen?

A

Lungefibrose, forkalkninger i hud

19
Q

Sys.sklerose/sclerodermi - behandling?

A

Raynaud : calcium-blokkere

Fibrose: D-pencillamin

20
Q

A. Temporalis - sygdom?

A

KÆMPECELLEARTRIT! Store kar!

Glanulomatøs vasculit i aorta og dens forgreninger - oftest kvinder

21
Q

A. Temporalis - symptomer?

A

Tindingehovedpine, tyggeclaudatio, synsforstyrrelser, træthed, hovedpine

Arterien: ophævet pulsation, øm, ødematøs, fortykken

22
Q

A. Temporalis - blodprøver?

A

SR-CRP–> øget
Øget celletal
Biopsi
Ophtalmoscopi

23
Q

A. Temporalis - behandling?

A

Prednisolon

24
Q

Små kar - ?

A

Wegener granulomatose, kutan leucocytoklastisk angitis

25
Q

Små kar -?

A

Rødme af hud, alveolær hæmoragisk, feber, træthed, vægttab