Bio: The Nervous and Endocrine Systems, Neurotransmitters, Parts of Brain Flashcards

(49 cards)

1
Q
Dendrites 
Soma
Myelin (what is it actually?) 
Schwann cells
oligodendrocyte
Axon hillock 
The impulse is send from what to what?
A

Dendrites send impulse to soma
Soma is basically where nucleus is and protein is made
Myelin = a CELL and insulator, so can increase speed of impulse transmission (Schwann cells serve as the myelinating cell of the PNS (they literally make the myelin) vs oligodendrocyte is name of myelin in CNS)

and “jumps” over nodes of ranvier -> saltatory conduction
Axon hillock connects soma to axon
impulse send from dendrites to axon terminus and all the way to the synaptic knobs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is the difference b/w unipolar, multipolar, and bipolar neurons

A

Unipolar -> Looks like soma in middle with regular axon terminal and multiple dendrites (sensory neuron)
Multipolar -> neurons with many dendrites (one we’re used to) (motor neuron)
Bipolar -> neurons with one dendrite (interneuron)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What is resting membrane potential and what perspective is it always from? That is threshold when Na+ voltage gated channels and K+ voltage gated channels open? Describe the channels you see in membrane and how this allows for this specific resting membrane potential

What happens when threshold is reached to Na+ and K+ voltage gated channels?

A

RMP = - 70mV
Threshold is -50mV

NOKIA321
Na+/K+ ATPase pumps out one net positive ion out
Na+/K+ ATPase establishes Na+ and K+ concentration gradients
many pos ions are lost through K+ leak channels (K+ leaks out of cell) (like “K bye”)
end result is that cell is more neg inside than out (-70mV)

in addition to these channels, there is K+ voltage gated channel and Na+ voltage gated channel but these only open when threshold is reached (-50mV) -> **When hit threshold Na channel works right away but K channel delayed, feel effect of Na first and it rushes inside down gradient

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Depolarization, hyperpolarization, repolarization
Equilibrium potential
What does the action potential look like, using the top 3 terms above?
Impulse is all or nothing

A

Depol -> move away from rest potential in the pos direction
Hyperpol -> move away from rest potential in neg direction
Repol -> return to rest potential
Equilibrium potential -> potential at which there is no driving force on an ion

Action potential:
Depolarization -> repolarization -> hyperpolarization -> repolarization

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Why is the impulse unidirectional?
What is the absolute and relative refractory period/ what is open/closed/inactivated? when do they occur?
What happens if add electrode in middle of axon?

A

Absolute refractory period -> absolutely impossible to fire another action potential, Na+ channels are inactivated, cell is too positive, near Na+ equilibrium potential

Relative refractory period -> possible but difficult to fire a second action potential, Na+ channels are now closed, cell it too neg, further from threshold, near K+ equilibrium potential

The impulse is unidirectional bc of the refractory period which begins when Na channels are inactivated (when membrane potential is repolarizing) and a neuron CANNOT fire another action potential no matter how strong a membrane potential depolarization is bc the voltage gates Na+ channels are inactivated after depolarization. They will not be able to be opened again until the membrane potential reaches the resting potential and the Na+ channels have returned to their “closed” state.

During the relative refractory period (right after the absolute refractory period), a neuron can be induced to transmit an action potential, but the depol required is greater than normal bc the membrane is hyperpolarized

If added electrode to middle of axon, impulse can go in either direction -> neither side is in refractory period

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Electrical synapses are ___junctions, always/sometimes excitatory, bidirectional, unregulated/regulated
common/rare in nervous system
very important to the organ system(s):

A

Electrical synapses are gap junctions, always excitatory, bidirectional (either cell can be pre/post synaptic, unregulated
Rare in nervous system, VERY IMPORTANT IN CARDIAC MUSCLE CELLS and smooth muscle

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q
Chemical synapse
Are excitatory/inhibitory, 
Synapsin bonds? 
Cytoskeleton filaments? 
How is Ca2+ involved?
A

Chemical synapse is opposite of electrical synapse
Can be excitatory or inhibitory, normal thing we find in nervous system
Synapsin bonds Keeps cytosketeton filaments and vesicles bound and these synapsin bonds can be broken by Ca2+
- There are Ca2+ voltage gated channel so that only when action potential arrives, can stimulate these voltage gated channels to open, so that Ca2+ (commonly found outside of cell) can go inside to break these bonds

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What is SSRI (selective serotonin re-uptake inhibitory?
Given: K+, Na+, Cl-, Mg2+, PO4 3-, Ca2+ -> where can the greatest concentration of these be found, inside or outside of neuron?

A

SSRI -> serotonin can stay in synaptic cleft for longer

Inside: k+, Mg2+, PO43-
Outside: Na+, Cl-, Ca2+
and these ions flow from high to low concentrations once certain channels open

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

*If you want to know how post synaptic cell will respond, what do you need to look at?
What is the difference between an inhibitory and excitatory neurotransmitters?
If a neurotransmitter causes entry of chloride into the postsynaptic cell, is the neurotransmitter excitatory or inhibitory?

A

NEED TO LOOK AT RECEPTOR, NOT NEUROTRANSMITTER -> EX GABA -> has “inhib effects” bc it bind to chlorine receptors
If a neurotransmitter such as acetylcholine is released at neuromuscular junction (b/w neuron and muscle cell) binds to its receptor on post synapic membrane, the receptor opens its associated sodium channel, allowing sodium to flow down its gradient into the cell, depolarizing the postsynaptic cell membrane . If a neurotransmitter such as acetylcholine opens a channel that depolarizes the postsynaptic membrane, the neurotransmitter is termed excitatory
Other neurotransmitters however, have the opposite effect, making the post synaptic membrane potential more negative than the resting potential or hyperpolarized so these neurotransmitters are called inhibitory

Chloride ions are negatively charged so entry into the cell would make the postsynaptic potential more negative, or

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What does Acetylcholinesterase do?

A

degrades acetylcholine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Neurons make one/more than one NT, and can respond to one/many
T/F: the amount of time neurotransmitter is in synaptic cleft adjusts response
T/F: takes more than one NT to have a significant effect on the postsynaptic cell

A

Neurons make one NT, and can respond to many
T
T

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

IPSP (inhibitory postsynaptic potentials) and EPSP (excitatory postsynaptic potential)

A

See printed out diagram

Get a mini depolarization from lil bit of neurotransmitter dumped to open ex. Na channel (green in diagram) = EPSP
But if dump more and more neurotransmitter to bind and open Na channel (green) then get past threshold and get large action potential peak
Get mini hyperpolarizaiton for chlorine receptor bc Cl-makes membrane potential more neg (red in diagram) =IPSP
But when bombarded with neurotransmitter to chlorine receptor get large hyperpolarization

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What is idea of summation?
Spatial vs Temporal?
What influences the intensity of a action potential?
Action potential is an all or nothing event

A

A post-synaptic neuron has many different neurons with synapses leading to it, however, each of these synapses can release neutrotransmitter many times per second. The “decision” by a possynaptic neuron whether to fire an action potential is determined by adding the effect of all of the of the synapses impinging on a neuron, both excitatory and inhibitory. This addition of stimuli is termed summation.
Spatial summation -> add up EPSPs and IPSPs from all the synapses on the post synaptic membrane are summed at a moment in time and majority rules (will tell you if overall excitatory or inhibitory)
Temporal summation -> add up frequent impulses from a single source, so basically a presynaptic neuron fires action potentials so rapidly that EPSPs or IPSPs
Intensity is coded by frequency

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What happens if an inhibitor of acetylcholinesterase is added to the neuromuscular junction, then the postsynaptic membrane will…

a) be depolarized by action potentials more frequently
b) be depolarized longer with each action potential
c) spontaneously depolarize

A

B

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What does afferent/efferent neuron mean? Where do they come from/go and why? Afferent neuron? Ventral root? Dorsal root?

A

afferent neurons = approaching the CNS from PNS
Efferent neurons = exit CNS to PNS
Dorsal = “enter through doors” and enter CNS
Ventral root = “leave through vents” and leave CNS

  1. Sensory info coming into CNS from PNS and carried on sensory neurons = afferent neurons (dorsal)
  2. Integration in CNS -> decision making, interneurons (entirely contained within CNS)
  3. Motor output (PNS) -> commands sent out to the body and carried on motor neurons (efferent neurons) exiting the CNS
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What are you able to feel/do if you cut dorsal root and get thumb injury?

A

If cut dorsal root, you can’t feel thumb but can move it

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Reflex -> what part of nervous system does it include?
What type of neuron is sensory neuron?
Motor neuron = _____neuron
Sensory neuron =____neuron

A

rapid integration to avoid potential injury
connects muscle to spinal coral
Sensory neuron is unipolar (weird looking one with head in middle)
For kick flip reflex -> you sense pressure from sensory neuron (afferent neuron), signal sent to spinal cord, and directly to motor neuron (efferent neuron) which causes quad muscle to contract and at the same time sensory neuron also sends signal to inhibitory interneuron which then sends signal to efferent motor neuron to relax the hamstring muscle, both of these actions cause you to kick up

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q
Reflex -> what part of nervous system does it include? 
What type of neuron is sensory neuron? 
Reciprocal inhibition (book) 
Motor neuron = \_\_\_\_\_neuron 
Sensory neuron =\_\_\_\_neuron
A

rapid integration to avoid potential injury
connects muscle to spinal coral
Sensory neuron is unipolar (weird looking one with head in middle)
For kick flip reflex -> you sense pressure from sensory neuron (afferent neuron), signal sent to spinal cord, and directly to motor neuron (efferent neuron) which causes quad muscle to contract and at the same time sensory neuron also sends signal to inhibitory interneuron which then sends signal to efferent motor neuron to relax the hamstring muscle, both of these actions cause you to kick up
This is called reciprocal inhibition

Motor neuron = efferent neuron
Sensory neuron = afferent neuron

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q
Dicephalon 
Hypothalamus
Pons
Medulla
Spinal cord
Cerebellum
Midbrain 
Limbic system 
Telencephalon
Corpus callosum

continues on next card

A

These can be labeled counter clockwise on brain diagram starting from top left

Dicephalon -> forebrain and includes thalamus and hypothalamus

  • thalamus contains relay and processing center for sensory info
  • Hypothalamus interacts with various parts of brain -> Maintains body homeostasis, contains centers for controlling emotions and autonomic functions and hormone regulation, controls pituitary gland

Telencephalon -> consists of two separate cerebral hemispheres, the cerebral hemispheres are connected by a thick bundle of axons called the corpus callosum
The telencephalon consists of two separate cerebral hemispheres, generally speaking the areas of the left and right hemispheres have the same functions. But the the left hemisphere controls the motor functions of the right side of the body, and the right hemisphere controls those of the left side. The left side of the brain is said to be dom and is responsible for speech, right hemisphere more concerned with visual-spatial reasoning and music.

Pons -> facial movement, balance, posture

Medulla -> basic vital/involuntary functions -> controls autonomic processes such as blood pressure, blood flow, HR, respiratory rate, swallowing, vomiting, cough, hiccup

Spinal cord -> simple reflexes, controls primitive processes such as walking, urination, and sex organ function

Cerebellum -> coordination of complex movement, BALANCE
(damage here result in poor hand eye coordination and balance)

Midbrain -> visual and auditory info, wakefulness and consciousness, startle reflex

Limbic system -> psychological response to emotional stimuli, helps memory storage

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Cerebrum/Cerebral cortex

A

*cerebral cortex is the outer layer of the cerebrum
cerebral cortex is an outer layer of gray matter plus an inner core of white matter connecting the cortex to the diencephalon

Cerebral cortex -> divided into 4 lobes (frontal, parietal, temporal, and occipital with specialized functions)

Frontal lobes initiate all voluntary movement, involved in complex, reasoning skills (judgement) and problem solving

Parietal lobes are involved in sensations (such as touch, temperature, pressure, vibration, etc.) and gustation (taste)

The temporal lobes process auditory (hearing), olfactory sensation and are involved in short-term memory, language comprehension, and emotion

The occipital lobes process visual sensation

21
Q

What makes the brain stem?

A

Midbrain, Pons, Medulla

22
Q

Epithalamus
Thalamus
Hypothalamus

A

Epithalamus -> pineal gland secretes melatonin - involved in sleep/wake cycles
Thalamus -> sensory relay station: sensory info come here first then gets distributed, relay info b/w spinal cord and cerebral cortex, EXCEPT: olfactory info (smell goes to olfactory bulbs)
Hypothalamus - (repeated from previous flashcard) interacts with various parts of brain -> Maintains body homeostasis, contains centers for controlling emotions and autonomic functions and hormone regulation, controls pituitary gland

23
Q

*White matter (IMPORTANT)
Gray matter
Memorize where white and gray matter is found in CNS vs PNS

A

White matter - myelinated portions of the nervous system (axon), cell to cell communication
CNS-brain = tract
CNS- spinal cord = tract/column (looks like outside portion of spinal cord lighter in diagrams)
PNS = nerve (duh)

Gray matter - soma; unmyelinated cell bodies and dendrites; (integration stations)
CNS-deep brain = nucleus (a cluster of neurons in the central nervous system, located deep within the cerebral hemispheres and brainstem)
CNS-brain surface = cortex
CNS- spinal cord = horn (looks inside portion of spinal cord darker in diagrams)
PNS = ganglion (leads to spinal cord)

24
Q

*What does a brocas injury do? Wernickes area injury?

What is a nerve tract?

A

A brocas injury -> can’t make speech

Wernickes area injury -> can’t comprehend speech
-> Makes yo say what?! Left temporal lobe

CNS is organized in bundles called tracts, or fasciculi. Ascending tracts carry impulses along the spinal cord toward the brain, and descending tracts carry them from the brain or higher regions in the spinal cord to lower regions.

25
Nervous splits into CNS vs PNS then what does PNS split into? Then what does one of those options split into?
CNS vs PNS PNS -> somatic (voluntary control of skeletal muscle) vs Autonomic (involuntary control of glands and smooth muscle) Autonomic -> Sympathetic ("fight or flight") vs parasympathetic ("rest and digest")
26
``` Somatic vs autonomic: Voluntary/invol? What types of organs/tissues involved? What neurotransmitters involved? Excitatory, inhibitory? How does signal get sent from CNS to target in terms of number neurons? ``` Dorsal root ganglion
Somatic -> voluntary, muscles, acetylcholine ONLY, excitatory, single neuron from CNS to target organ and all somatic sensory neurons have a long dendrite extending from the sensory receptor toward the soma, which is located outside the CNS in a dorsal root ganglion Autonomic -> involuntary, all other organs, acetylcholine or norepinephrine (also known as noradrenaline) -> For autonomic there are 2 neurons -> one ends in norepinephrine (sympathetic) and the other in acetylcholine (parasympathetic) (either stimulate or inhibit)
27
Acetylcholine vs norepinephrine When, where is epinephrine/adrenaline released?
``` Acetylcholine = parasympathetic, rest and digest Norepinephrine = sympathetic, fight or flight ``` Upon activation of the sympathetic system, the adrenal gland is stimulated to release epinephrine, also known as adrenaline
28
Golgi tendon organs
Golgi tendon organs sense tension in tendons when lift something It responds to increased muscle tension or contraction as exerted on the tendon, by inhibiting further muscle contraction.
29
``` 5 classes of Sensory Receptors: Mechanoreceptors Chemoreceptors Thermoreceptors Nociceptors Photoreceptors/Electromagnetic receptors ``` Where would muscle spindle, O2 receptors, taste buds, olfactory sensors, golgi organs, rods/cones fit?
Mechanoreceptors -> stim by physical shape changes e.g. baroreceptors, golgi tendon organs, touch receptors, muscle spindle (detect muscle stretch) etc. Chemoreceptors -> stimulated by chemicals e.g. olfactory sensors, taste buds are gustatory receptors, pH receptors, O2 receptors, etc. Thermoreceptors -> stimulated by temperature e.g. hot and cold receptors Nociceptors: stimulated by pain free nerve endings that respond to touch, chemicals, heat, etc. Photoreceptors/Electromagnetic receptors: stimulated by light e.g. rods and cones
30
Absolute threshold | Difference threshold
Absolute threshold -> MINIMUM stimulus required to trigger a receptor ex. Dog has lower absolute threshold and can smell better Difference threshold -> amount of change that is required to occur before we notice it ex. you forgot you were wearing clothes bc no change detected. The minimal noticable difference b/w any two sensory stimuli
31
Sensory Adaption Bottom-Up processing Top-Down processing
Sensory Adaption -> is a decrease in firing frequency when the intensity of a stimulus remains constant, ignore unchanging stimuli, can be retriggered if stimulus change Bottom-Up processing -> 1. Sensory receptors register info 2. Sensory neuron send info to the bran 3. Brain identifies the info Top-Down processing 1. Brain applies prior knowledge and experience 2. Forms a holistic view of what's going on
32
Iris Lens Cornea Pupil
Iris -> colored part of eye. regulates the diameter of pupil Lens -> biconvex structure that focuses light on the retina Cornea -> external transparent layer of eye Pupil -> black opening in middle of eye
33
``` Ciliary Muscles Fovea centralis retina optic disk optic nerve ```
Ciliary Muscles -> muscles that regulate the curvature of the lens Fovea centralis -> responsible for extreme visual acuity (highest density of cones) when you look directly at something, you focus its image on the fovea retina -> layer at the back of eye sensitive to light optic disk -> blind spot. Place on retina where optic nerve forms -> Blind spot has many ganglion cells so blocks light and you are blind there optic nerve -> bundle of axons leaving the eye towards the brain
34
Where does the signal go from retna?
Goes to photoreceptors (rods or cones) then to bipolar cells then to ganglion cells then to occipital lobe of cerebral cortex (image processing) No light can pass through region when ganglions are bc blocks
35
Where does the signal go from retna? What happen in dark vs light and on center vs off center?
Goes to photoreceptors (rods or cones) then to bipolar cells then to ganglion cells then to occipital lobe of cerebral cortex (image processing) No light can pass through region when ganglions are bc blocks Bc of the rods and cones depolarization in the dark, both types of photoreceptors release the neurotransmitter glutamate onto the bipolar cells. Upon the absorption of a photon of light and subsequent hyperpolarization, the photoreceptor release less glutamate, or stop releasing it altogether Some bipolar cells are "on center" and are inhibited by glutamate. This means that when the photoreceptor is in the dark and releasing glutamate, the on-center bipolar cell releases very little or no neurotransmitter. However, when the photoreceptor is in the light (light is ON the center), and stops releasing glutamate, the inhibition of the on-center bipolar cell stops, and the bipolar cell increases its release of neurotransmitter. "Off center" bipolar cells work in the opposite manner; they are stimulated by the glutamate released when the photoreceptor is in the dark, and inhibited when glutamate stops being released in the light Dark, on center -> no action potential Dark, off center -> action potential Light, on center -> action potential Light, off center -> no action potential
36
``` Ear terms (know parts of ear) Pinna Auditory canal Typanic membrane Ossicles Malleus Incus Stapes Semicircular canals Cochlea Eustachian tube ```
``` The pinna and auditory canal = outer ear Typanic membrane = ear drum Three small bones -> called ossicles = Malleus, Incus, Stapes Eustachian tube (auditory tube) -> connects throat with middle ear, allows pressure to be equalized ```
37
How do we hear? Perilymph and endolymph? Basilar membrane Tectorial membrane
1. Sound waves go down auditory canal and bounce on timpanic membrane 2. This causes auditory ossciles to vibrate back and forth 3. Which sends waves to fluid in cochlea (the outer structures filled with fluid called perilymph), waves sent to perilymph which then send waves down central region called endolymph 4. Then we get vibration in basilar membrane (supports receptors called hair cells) and movement of hair cells 5. The hair cells are in contact with the tectorial membrane (stationary) and cilia of hair cells are dragged across the tectorial membrane 6. hairs get bent and since they are mechanoreceptors, they release neurotransmitter onto auditory nerve 7. Auditory neuron transmits the signal to the brain
38
How do we determine pitch from loudness?
These are determined by which region of basolar membrane that gets stimulated most strongly high pitch tones are high freq and low pitch tones are low freq Thick at “base” and thin at “leaves” like a tree at the beginnign part of basolar membrane, it is very stiff and thick and at end it's thinner, floppy a low freq pitch/tone do not have enough strength to vibrate the thick part of membrane and high freq tone are better at vibrating the thicker beginning part of membrane Depending on which region of basolar membrane is most stimulated, the brain can interpret pitch Loudness is determined by amplitude -> soft sound, small amplitude, loud sound, larger amplitude
39
Semicircular canals | Vestibule
Semicircular canals -> important for rotational equilibrium/dynamic equilibrium ex. 3D space of head, head turning, spinning Vestibule -> important for static equilibrium ex. forward momentum, no spinning but plane of equilibrium shifting when chair you were sitting in started leaning backwards
40
Summary: From sound to Hearing
Sound waves -> auricle -> external auditory canal -> tympanic membrane -> malleus -> incus -> stapes -> oval window -> perilymph -> endolymph -> basilar membrane -> auditory hair cells -> tectorial membrane -> neurotransmitters stim bipolar auditory neurons -> brain -> perception
41
Vestibular complex Semicircular canals Vestibule
Semicircular canals -> important for rotational equilibrium/dynamic equilibrium ex. 3D space of head, head turning, spinning Vestibule -> important for static equilibrium ex. forward momentum, no spinning but plane of equilibrium shifting when chair you were sitting in started leaning backwards
42
Equilibrium potential for K+? *Gray vs White matter? Horn? Tract? Column? Nucleus?
-90mV White matter = myelinated axons in CNS and PNS White matter in brain = a tract White matter in spinal cord = tract or column White matter in PNS = nerve Gray matter = Unmyelinated cell bodies in CNS and PNS nucleus = gray matter in brain Cortex = gray matter on the surface of brain Horn = gray matter in spinal cord Ganglion = gray matter in PNS
43
What is a proprioreceptor? | Muscle spindle?
Proprioreceptor refers to awareness of self (i.e. awareness of body part position) and is known as your kinesthetic sense An important example of a proprioreceptor is the muscle spindle, a mechanoreceptor that detects muscle stretch Other proprioreceptor includes Golig tendon organs which detect tension in tendons
44
extra? Myopia Hyperopia
Myopia -> nearsightedness, too much refraction at the lens or an abnormally long eyeball results in a focal length that is too short Hyperopia -> farsightedness, too little refraction at the lens or an abnormally short eyeball results in a focal length that is too long
45
What does the posterior pituitary do? Anterior? Do they make/secrete hormones?
posterior -> composed of axons which descend from the hypothalamus, these hypothalamus neurons are an example of neuroendocrine cells (neurons which secrete hormones into the bloodstream) doesn't make hormones, it just stores ADH and oxytocin for later release anterior is a normal endocrine gland and is controlled by hypothalamic releasing and inhibiting factors (tropic hormones)
46
``` Basal nuclei (also called "cerebral nuclei" or basal ganglia function? ```
composed of gray matter and located deep in cerebral hemispheres Regulate body movement and muscle tone, coordination of learned movement patterns, general rhythm movements (arm and leg movements when walking) The basal nuclei and cerebellum work together to process and coordinate movement initiated by the primary motor cortex; the basal nuclei are inhibitory (preventing movement), while cerebellum is excitatory
47
Name function of following neurotransmitter(s): Dopamine Seratonin Melatonin
Dopamine -> reward, mood, pleasure, smooth motor movements, focus and attention, shortages can lead to depression, lethargy and difficulty coordinating motion Seratonin -> Mood stabilizer, Mood, digestion, sleep, memory, sexual desire, shortages can lead to: aggression, compulsive behavior, overeating, and depression Melatonin -> circadian rhythm, sleepiness, sleep initiation (melatonin is technically a "neurotransmitter-like substance", shortages lead to insomnia
48
Name function of following neurotransmitter(s): Gamma Aminobutyric Acid (GABA) Acetylcholine
GABA -> Primary inhibitory neurotransmitter in the brain, shortages can lead to stress and anxiety, depression, ADHD, Panic Disorders, etc Acetylcholine -> excitation at neuromuscular junction, parasympathetic nervous system activity Shortages can lead to dysfunction of Gi tract and paralysis
49
Name function of following neurotransmitter(s): Epinephrine (adrenaline) Norepinephrine (noradrenaline) Glutamate
Two similar molecules both involved in fight or flight response, sympathetic nervous system activation (both are hormones and neurotransmitters) Shortages can lead to fatigue, lack of focus, apathy Glutamate -> primary excitatory neurotransmitter in brain, learning, memory, long-term potentiation Shortages can lead to fatigue, low concentration and energy