Flashcards in Biochem 2 Ex 1 Deck (200)
What breaks glucose?
What are the products of glycolysis?
ATP, NADH, pyruvate, lactate and alanine
Where does the pyruvate from glycolysis go?
prep step for Krebs Cycle, gets turned into acetyl-CoA, which enters into Krebs.
What does pyruvate from get changed into in the Krebs Cycle prep step?
What is the first step of glycolysis after the glucose has entered the cell?
hexokinase turns glucose into glucose-6-phosphate
What is the second step of glycolysis?
phosphoglucose isomerase turns glucose-6-phosphate into fructose-6-phosphate
What is the third step of glycolysis?
phosphofructokinase turns fructose-6-phosphate into fructose-1,6-bisphosphate
What is the fourth step of glycolysis?
aldolase splits fructose-1,6-phosphate into glyceraldyhyde-3-phosphate (important) and dihydroxyacetone phosphate
What is the fifth step of glycolysis?
glyceraldyhyde-3-phosphate dehydrogenase turns glyceraldyhyde-3-phosphate into 1,3-bisphosphoglycerate
What is the sixth step of glycolysis?
phosphoglycerate kinase turns 1,3-bisphosphoglycerate into 3-phosphoglycerate
What is the 7th step of glycolysis?
phosphoglycerate mutase turns 3-phosphoglycerate into 2-phosphoglycerate
What is the 8th step of glycolysis?
enolase turns 2-phosphoglycerate into phosphoenolpyruvate
What is the 9th step of glycolysis?
pyruvate kinase turns phosphoenolpyruvate into pyruvate
What is the 10th step of glycolysis?
lactate dehydrogenase turns pyruvate into lactate
Where does glycolysis happen?
in the cytosol
What do Kinase enzymes do?
transfer phosphate groups
What is PFK?
What is a diphosphate?
two joined phosphates
What is a bis-phosphate?
two separate phosphates
What is the rate limiting enzyme in glycolysis?
What is one glucose split into in the process of glycolysis?
1 glyceraldehyde-3-phosphate and 1 dihydroxyacetone phosphate or two glyceraldehyde-3-phosphates
Who many pyruvates do we get from one glucose?
Can fructose enter glycolysis?
How does pH effect PFK?
decreased pH inhibits PFK
How does citrate effect PFK?
citrate inhibits PFK
How does inhibition of PFK effect hexokinase?
if PFK is inhibited, hexokinase is inhibited
Where do we find glucokinase?
liver and B-cells of the pancreas
What is glucokinase?
alternative form of hexokinase
When does glucokinase make G6P?
when glucose is abundant (high Km)