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Flashcards in Biochem 2 Ex 1 Deck (200)
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1

What breaks glucose?

glycolysis

2

What are the products of glycolysis?

ATP, NADH, pyruvate, lactate and alanine

3

Where does the pyruvate from glycolysis go?

prep step for Krebs Cycle, gets turned into acetyl-CoA, which enters into Krebs.

4

What does pyruvate from get changed into in the Krebs Cycle prep step?

Acetyl-CoA

5

What is the first step of glycolysis after the glucose has entered the cell?

hexokinase turns glucose into glucose-6-phosphate

6

What is the second step of glycolysis?

phosphoglucose isomerase turns glucose-6-phosphate into fructose-6-phosphate

7

What is the third step of glycolysis?

phosphofructokinase turns fructose-6-phosphate into fructose-1,6-bisphosphate

8

What is the fourth step of glycolysis?

aldolase splits fructose-1,6-phosphate into glyceraldyhyde-3-phosphate (important) and dihydroxyacetone phosphate

9

What is the fifth step of glycolysis?

glyceraldyhyde-3-phosphate dehydrogenase turns glyceraldyhyde-3-phosphate into 1,3-bisphosphoglycerate

10

What is the sixth step of glycolysis?

phosphoglycerate kinase turns 1,3-bisphosphoglycerate into 3-phosphoglycerate

11

What is the 7th step of glycolysis?

phosphoglycerate mutase turns 3-phosphoglycerate into 2-phosphoglycerate

12

What is the 8th step of glycolysis?

enolase turns 2-phosphoglycerate into phosphoenolpyruvate

13

What is the 9th step of glycolysis?

pyruvate kinase turns phosphoenolpyruvate into pyruvate

14

What is the 10th step of glycolysis?

lactate dehydrogenase turns pyruvate into lactate

15

Where does glycolysis happen?

in the cytosol

16

What do Kinase enzymes do?

transfer phosphate groups

17

What is PFK?

phosphofructokinase

18

What is a diphosphate?

two joined phosphates

19

What is a bis-phosphate?

two separate phosphates

20

What is the rate limiting enzyme in glycolysis?

phosphofructokinase

21

What is one glucose split into in the process of glycolysis?

1 glyceraldehyde-3-phosphate and 1 dihydroxyacetone phosphate or two glyceraldehyde-3-phosphates

22

Who many pyruvates do we get from one glucose?

two

23

Can fructose enter glycolysis?

yes

24

How does pH effect PFK?

decreased pH inhibits PFK

25

How does citrate effect PFK?

citrate inhibits PFK

26

How does inhibition of PFK effect hexokinase?

if PFK is inhibited, hexokinase is inhibited

27

Where do we find glucokinase?

liver and B-cells of the pancreas

28

What is glucokinase?

alternative form of hexokinase

29

When does glucokinase make G6P?

when glucose is abundant (high Km)

30

Where is hexokinase found?

muscle