Biochem Mnemonics Flashcards

1
Q

Functions of the different RNA polymerases I, II and III?

A

I,II,II = R.M.T

rRNA, mRNA, and tRNA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Name the stop codons?

A
UGA = U Go Away
UAA = U Are Away
UAG = U Are Gone
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What are the functions of the Golgi apparatus?

A

Su.Pro.Dis.N.O.Man. !

Sulfation of sugars in proteoglycans and tyrosine
Proteoglycan assembly
Distribution center of proteins and lipids
N-oligosacc. modification on Asn
O-oligosacc. addition to serine and threonine
Mannose-6-Phophate addition to lysosomal proteins

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Collagen types?

A

B.e C.ool R.ead B.ooks

Bone Cartilage Reticulin Basement membrane

Type X - epiphyseal plate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What is S-adenosylmethionine?

A

SAM the methyl donor man

SAM regeneration is dependent on B12

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

The TCA cycle intermediates, starting from Citrate….?

A

C.an I. K.eep S.elling S.ex F.or M.oney O.fficer?

Citrate
Isocitrate
(alpha)-Ketoglutarate
Succinyl CoA
Succinate
Fumarate
Malae
Oxaloacetate
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Name the enzymes responsible for gluconeogenesis?

A

P.athway P.roduces F.resh G.lucose

Pyruvate carboxylase (mitochondria, the rest are cytosolic)
PEP carboxykinase
Fructose-1,6 bisphosphatase
Glucose-6-phosphatase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

G6PD deficiency?

A
5H's - .
HMP shunt enzyme deficiency
Hurts RBCs by exposing them to oxidation, which normally is prevented by NADPH
Hemoglobin is altered, precipitates
Heinz bodies form
Hemolytic anemia results
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Name the essential amino acids?

A

P.v.t. T.I.M. H.A.L.L.

Phe
Val
Thr
Typ
Ile
Met
His
Arg
Leu
Lys
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Name the components (intermediates and enzymes) of the urea cycle

A

O.rdinarily, C.areless C.rappers A.re A.lso F.rivolous A.bout U.rination

Ornithine
Carbamoyl phosphate
Citrulline
Aspartate
Argininosuccinate
Fumarate
Arginine
Urination
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Cystinuria is caused by a defect of…?

A

Renal tubular amino acid transporter for C.O.L.A.

Cystine
Ornithine
Lysine
Arginine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Maple Syrup Urine disease?

A

Blocked degradation of branched amino acids (Ile, Val, Leu)

I. L.ove V.ermont Maple Syrup

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Lesch-Nyhan syndrome?

A

L.N.S. = Lacks Nucleotide Salvage (purine)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What does the liver do generally during the fasting state?

A

In the Phasting state, Phosphorylate.””

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Which tissues don’t need insulin for glucose uptake?

A

BRICK L:

Brain
RBCs
Intestine
Cornea
Kidney
Liver
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What are the anabolic affects of insulin?

A

Gluck Sometimes Tries to Glide Professionally

Increased:
Glucose transport
Sodium retention by kidneys
Triglyceride snythesis and storage
Glycogen synthesis and storage
Protein synthesis by the muscles
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Pompe’s?

A

Pompe’s trashes the Pump”

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Name the glycogen storage diseases?

A

V.ery P.oor C.arbohydrate M.etabolism

Von Gierke’s
Pompe’s
Cori’s
McArdle’s

19
Q

Niemann-Pick?

A

NO MAN PICKS his nose with his SHPINGER” (shpingomyelinase)”

20
Q

Tay Sachs?

A

Tay SaX laX heXosaminidase

21
Q

Hunter’s?

A

HUNTERS aim for the X” (X recessive”

22
Q

What are the major apolipoproteins and what do they do?

A

A-1 Activates LCAT
B-100 Binds to LDL receptor
C-II Cofactor for lipoprotein lipase
E - mEdiates Extra (remnant) uptake

23
Q

Symptoms of porphyrias?

A
5P's - 
Painful abdomen
Pink urine
Polyneuropathy
Psychological disturbances
Precipitated by drugs
24
Q

How to treat methemoglobinemia?

A

Treat toxic levels of METHemoglobin with METHylene blue””

25
Imprinting: Angelman's and Prader-Willi syndrome?
AngelMAN's and P.rader-Willi (P.aternal)
26
Duchenne's - the molecular problem?
Deleted dystrophin
27
Trinucleotide repeat expansion diseases?
Try hunting for my fried eggs."
28
Fragile X syndrome?
Xtra-large testes, jaw, ears
29
Edward's syndrome: what causes it?
Election age = 18 | T.risomy 18
30
Patau's syndrome: what causes it?
Trisomy 13 | P.uberty = 13
31
Cri-du-chat?
CRI D.U. C.H.A.T ``` Dumb - mental retardation Underdeveloped brain - microcephaly Cardiac abnormalities Hypertelorism Asian eyes" - epicanthal folds ```
32
22q11 syndromes
``` CATCH 22 Cleft palate Abnormal facies Thymic aplasia --> T cell deficiency Cardiac defects Hypocalcemia secondary to parathyroid aplasia ```
33
Vitamin A is aka?
Retinol (think RetinA)
34
Beriberi?
Ber1Ber1 - Vitamin B1 deficiency
35
Wernicke-Korsakoff?
Were you drinking
36
Vitamin B2... aka? Deficiency causes?
I C.an S.ense C.razy F.lavor FAD and FMN are derived from RiboFlavin Cheilosis Stomatitis (angular) Corneal vascularization
37
Vitamin B3?
B.e Ni.ce, or you'll get Pellagra"
38
Biotin?
AVIDIN in egg whites | AVIDly binds biotin
39
Vitamin E
E is for Erythrocytes""
40
Vitamin K
K for Koagulation""
41
Kwashiorkor?
Protein-deficient MEAL: Malabsorption Edema Anemia Liver (fatty)
42
G protein linked 2nd messengers via phospholipase C?
H.A.V. 1 M & M | H1 a1 V1 M1 M3
43
G protein linked 2nd messengers via Adenylyl cyclase?
MAD 2s M2 a2 D2 (via Gi) [the others in this group operate via Gs]