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Chronic Kidney Disease > Biochemistry > Flashcards

Flashcards in Biochemistry Deck (8)
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1

What are the excretory functions of the kidneys?

- Remove waste products
- Remove excess fluid
- Regulate acid base balance - pH
- Regulate electrolyte levels

2

What are the secretory functions of the kidneys?

- Regulate BP
- Regulate RBC production (EPO)
- Regulate calcium uptake (active vitD)

3

What is the definition of CKD?

Markers of kidney damage and GFR of less than 60ml/min/1.73m^2 on at least 2 occasions separated by 90 days.

4

What are the complications of CKD?

- CKD mineral bone disease - hypercalcaemia, hyperparathyroidism
- Renal anaemia
- Metabolic acidosis
- Hyperkalaemia

5

What are the contraindications of HD?

- Inability to achieve suitable vascular access
- Dementia
- HF
- Bleeding disorder
- Low BP

6

What are the contraindications of PD?

- IBD
- Ischaemic bowel
- Acute diverticulitis
- Abdominal access
- 3rd trimester of pregnancy
- Abdominal hernias
- Blind
- Stomas/VP shunt

7

What are the contraindications for a renal transplant?

- Concurrent or recurrent infection
- Active malignancy

8

What are the most common causes of CKD?

- Diabetes
- HTN
- Glomerulonephritis
- Renovascular disease