Flashcards in Biochemistry Deck (8)
What are the excretory functions of the kidneys?
- Remove waste products
- Remove excess fluid
- Regulate acid base balance - pH
- Regulate electrolyte levels
What are the secretory functions of the kidneys?
- Regulate BP
- Regulate RBC production (EPO)
- Regulate calcium uptake (active vitD)
What is the definition of CKD?
Markers of kidney damage and GFR of less than 60ml/min/1.73m^2 on at least 2 occasions separated by 90 days.
What are the complications of CKD?
- CKD mineral bone disease - hypercalcaemia, hyperparathyroidism
- Renal anaemia
- Metabolic acidosis
What are the contraindications of HD?
- Inability to achieve suitable vascular access
- Bleeding disorder
- Low BP
What are the contraindications of PD?
- Ischaemic bowel
- Acute diverticulitis
- Abdominal access
- 3rd trimester of pregnancy
- Abdominal hernias
- Stomas/VP shunt
What are the contraindications for a renal transplant?
- Concurrent or recurrent infection
- Active malignancy