BIOLOGY LECTURE FINALS Flashcards
(106 cards)
GREGOR MENDEL AND ELEMENTARY GENETICS
The term genetics was derived from the greek word ____ meaning ____ .
This term was first coined by ____ in 1906.
_____ is the branch of biology that deals with the principles of heredity and variation in all living things.
Gen
To become/ to grow into something
William bateson
Heredity
GREGOR MENDEL AND ELEMENTARY GENETICS
____ is our genetic heritage, passing from the parents to their offspring. These traits can be physical, a disease or behavioral and _____ is the difference in the genetic make up or physical appearance of a different organisms
Heredity
Variation
GREGOR MENDEL AND ELEMENTARY GENETICS
BRANCHES OF BIOLOGY
1. ____ Field that studies the structure and function of genes at a molecular level.
2. ____ Study the processes by which organisms grow and develop
3. ____ concerned with the study of the structure and function of the cell, especially the chromosomes
4. ____ the study of how genetic variation leads to evolutionary change
5. ____ study of the fundamental relationship between genes, protein, and metabolism. This involves the study of the cause of many specific heritable disease
Molecular genetics
Developmental genetics
Cytogenetics
Evolutionary genetics
Biochemical genetics
GREGOR MENDEL AND ELEMENTARY GENETICS
BRANCHES OF GENETICS
6. ___ the field of study that examines the role of genetics in animal (including human) behavior
7. ___ the study of allele frequency distribution and change under the influence of the four main evolutionary processes: natural selection, genetic drift, mutation and gene flow
8._____ the study of continuously measured traits (such as height or weight) and their mechanisms
Behavioral genetics
Population genetics
Quantitative genetics
APPLICATION OF GENETICS (5)
1. This includes selective breeding, producing high yielding crops, advancements in meat production through breeding that supplied the protein needs, and the use of selected microbial strains that improved the fermentation of foods and food products.
2. Genetic diseases and abnormalities have been identified and appropriate preventive measures are prescribed. Knowing the nature of these defects made it easier to take the preventive steps, including gene therapy.
3. Knowledge of the inheritance of certain desirable or undesirable characteristics will help individuals, prospective parents, and families to understand their genetic history and adapt to the most effective way of treatment, if necessary.
4. Genetics helped solve problems of disputed parentage in settling child support, estate claims or even baby mix-up in hospitals. DNA profiles or fingerprints of suspects have been found to be an accurate tool in identifying criminals.
5. This involves joining of DNA segments from different biological sources producing genetically modified organism (GMO) or transgenic plants, animals, or microorganisms. Therapeutic proteins, hormones and vaccines are also produced using this technology.
Plant, animal and microbial improvement
Medicine
Genetic counseling
Legal application
Recombinant DNA Technology
THEORY OF _____ by ____
This theory suggests that ____ small particles in the body were formed everywhere in the man’s body and such gemmule reflected the characteristics of the body part from where it was formed.
Pangenesis
Charles darwin
Gemmules
_____ proposed his theory of ____ based on the pangenesis theory. Body modifications acquired by use or disuse could be transmitted to the offspring because the gemmules formed reflected such modifications. He stated that CHANGE IS WHAT ORGANISMS WANT OR NEED
Jean Baptiste de Lamarck
Theory of Inheritance of acquired characteristics
____ disproved the theory of pangenesis with his theory of ____.
This theory proposed that ____ or sex cells perpetuated themselves in reproduction generation after generation. While ____ or body cells were reproduced by germplasm to protect and reproduce itself.
August weisman
Germplasm theory
Germplasm
Somatoplasm
He discovered that hereditary characteristic were determined by elementary factors that are transmitted between generations. He believe that ___ is inherited from generation to generation that each descendant has a physical copy of this material
Gregor mendel
Gene
MENDELIAN OBSERVATION
• Garden peas are ____, they are true-breeding plants. They always produce offspring that look like the parent
• Garden peas mature within ___
• Large quantities of garden peas could be ___
Mendel applied _____ he classified the hybrid ___ and determined their perspective frequencies
Self-pollinating
One season
Cultivated simultaneously
Quantitative approach
Progenies
Mendel observed seven characteristics from his garden peas, each with two contrasting traits.
• For the seeds, he observed the ___ (either round or wrinkled)
• ____ (yellow or green)
• Flower color ( white or violet)
• ____ (full or constricted) and color ___
• ___ (axial pods with flowers along terminal pods with flower at top) and ___ (long or short)
• Mendel confirmed that he was using ___ for white or violet flower color (How mendel perform his experiment)
Form
Color
Pod form
Yellow or green
Stem place
Stem size
True-breeding plants
MENDELIAN OBSERVATION
•___ are those that are inherited unchanged in a hybridization while ___ disappear in the offspring of hybridization but reappear in the offspring of the hybrids
Dominant traits
Recessive
CHROMOSOMES THEORY OF INHERITANCE
In 1903 ____ and ____ independently suggested the pair factors (in Mendel’s observation) is paralleled by the separation of homologous chromosomes during meiosis
• The individual genes are found at specific locations on chromosomes, and the behavior of chromosomes during meiosis can explain why genes are inherited, these observation proposed the ____
• This theory was confirmed when ___ discovered the sex chromosomes on his study about fruit flies
Walter sutton and theodor boveri
Chromosome theory of inheritance
Thomas hunt morgan
CHROMOSOMES
The term chromosomes comes from the greek words ___ and ___ which stands for color and body. Chromosomes are thread like structure located inside the nucleus of the cell. The ___ provides support for the structure of chromosomes coiling it and keeping it highly condensed
Chroma
Soma
Protein histone
CHROMOSOMES
Chromosomes are also ___ females have two _ Chromosomes (XX) while males have one _ and one _ (__)
Chromosomes has different parts :
• ___ the constricted region of the chromosomes. It help keep chromosomes properly aligned during cell division and the attachment site for the sister chromatids
• ___ are located at the ends of the chromosomes. Protect the ends of the chromosomes and sustain chromosome stability
• ___ region on either side of the centromere.
• The short arm ___
• The long arm ___
Sex determinants
X (XX)
X & Y (XY)
Centromere
Telomeres
Chromosomes arms
P arm
Q arm
TYPES OF CHROMOSOMES
• Chromosomes can be ____ when centromere occupies the terminal position, so that the chromosomes has just one arm.
• ____ when the centromere occupies a sub-terminal position (one arm is very long and other is very short)
• ____ Chromosomes are when centromere is positioned slightly awar from the mid-point so that the two arms are unequal.
• ____ is when centromere lies in the middle of chromosomes so that the two arms are almost equal
Telocentric
Acrocentric
Sub-metacentric
Metacentric
DNA STRUCTURE
The DNA are made up of ____
• In 1944 ___, ____ and ___ concluded that the DNA is the genetic material. But DNA was first identified in the late 1860s by swiss chemist ____
• DNA is composed of repeating nucleotides, which are made up of a ___ (ribose or deoxyribose) , a ___ (purine (G,A) And pyrimidines (C,T) and ___
Bases ( Cytosine, Guanine, Adenine, Thymine)
Deoxyribonucleic acid
Oswald avery, colin macleod and maclyn mcCarty
Friedrich miescher
Pentose sugar
Nitrogenous base
Phosphoric acid
CENTRAL DOGMA
First used by ___
Summarize the event from DNA to RNA to protein production. It explains the flow of genetic information in making functional proteins.
• This describes the step-by-step process of the duplication of the DNA (__), how DNA is transcribed into RNA (__) and how RNA is translated into proteins (__)
Francis crick
Central dogma
Replication
Transcription
Translation
CENTRAL DOGMA (REPLICATION)
• During DNA replication, each of the two strands that make up the double helix serves as a template from which new strands are copied. The new strand will be complementary to the parental or “old” strand. This is known as ___ replication.
• There are specific nucleotide sequence called ____ at which replication process begins. When the helicase unwinds and opens the DNA, a Y-Shaped structure called ____ is formed
Semiconservative replication
Origins of replication
Replication fork
DNA (TRANSCRIPTION)
• The region of unwinding is called a ___
• Transcription proceeds from one of the two DNA strands, called the ____ RNA polymerase moves along the template strand, separates the two strands while complementing DNA template nucleotide with RNA nucleotides.
- ___ are complexed with ribosomal proteins to form ribosomes, which are protein synthesizing organelles of the cell.
- ___ provides the template that contains the nucleotide code for the amino acid sequence of a protein.
- ___ transfer amino acids from the cytoplasm to the ribosomes
Transcription bubbles
Template strand
rRNA
mRNA
tRNA
DNA (TRANSLATION)
The process by which the mature mRNA is used as a template for synthesizing protein. Carried out in ribosomes. Each amino acid is defined by a three nucleotide sequence called a ___
• The relationship between a nucleotide codon and it’s corresponding amino acid is called the ___
• Three of the 64 codons terminate protein synthesis and release the polypeptide from the translation and machinery. They are UAA, UAG and UGA they are called ___
Codon
Genetic code
Stop codons
GENES AND GENE INTERACTIONS
Mendel concluded that individuals had two discrete copies of the characteristics that are passed individually to offspring. He called these as ____ which we call now genes
• A ___ is the unit of heredity occupying a particular location on the chromosomes and passed on to offspring.
• ___ are gene variants that exist at the same relative locations on homologous chromosomes
• The observable traits expressed by an organism are reffered to as its ___ (it is referred to the appearance of an organism) (height, eye color, etc.)
• organisms underlying genetic makeup is called its ___
Factors
Genes
Alleles
Phenotype
Genotype
GENES AND GENETIC INTERACTIONS.
____ is a hereditary factor express itself when present
____ Is a hereditary factor that is hidden and Expressed only when two recessive alleles are combined
• Mendel used in his experiment were each ____ for the trait he was studying. This means that an organism has two identical alleles, one on each of their homologous chromosomes.
• When p plants with contrasting traits were cross fertilized, all of the offspring were ___ for the contrasting traits meaning their genotype had different alleles for the gene being examined (Bb)
Dominant allele
Recessive
Homozygous
Heterozygous
LAW OF DOMINANCE
____ this states that heterozygote, one trait will conceal the presence of another trait for the same characteristics. Rather than both alleles contributing to a phenotype, the dominant allele will be expressed exclusively.
Law of dominance