Biology of Oxygen Flashcards
1
Q
Where are oxygen levels sensed?
A
Carotid Bodies
2
Q
What are 4 physiological responses in acute hypoxia?
A
- increase breathing rate
- Constrict vessels
- Increase HR
- Dilate peripheral blood vessels
3
Q
What is the main nerve responsible for taking signal from carotid body to CNS?
A
Glossopharyngeal nerve (CN IX)
4
Q
What are the 3 components of the carotid body?
A
Nerve fibre, type 1 cells, type 2 cells
5
Q
What type of cell is the type 1 cell?
A
Glomus cells - sense O2 and CO2, excitable
6
Q
What type of cells are type 2 cells?
A
Glial like, non-excitable
7
Q
What happens in the glomus cells in low PO2?
A
Low PO2 - K+ channels close - cell depolarizes - VG Ca2+ channels open - Ca2+ entry - degranulation of DA vesicles - DA sends signal to glossopharyngeal nerve - medullary centre increases respiratory rate
8
Q
A
9
Q
A
