biology sem 2 unit 1 Flashcards

(50 cards)

1
Q

what does dna stand for?

A

deoxyribonucleic acid

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2
Q

what are the 2 reasons why dna is unique

A

it contains our genetic code and copies itself exactly

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3
Q

what are the building blocks of dna

A

nucleotides

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4
Q

what are the 3 parts of a nucleotide

A

phosphate, sugar(deoxyribose), and nitrogen base

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5
Q

what are the 4 nitrogen bases for dna

A

adenine, thymine, cytosine, guanine

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6
Q

what are the purines and how many rings do they have

A

adenine and guanine, 2 rings

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7
Q

what are the pyrimidines and how many rings do they have

A

cytosine and thymine, 1 ring

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8
Q

when and who discovered the double helix structure of dna

A

1953; wilkins, watson, franklin, crick

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9
Q

what did Erwin Chargaff discover

A

In any sample of dna thymine and adenine have close to the same percentages, guanine and cytosine then also have close to the same percentages

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10
Q

what is the backbone of dna made up of

A

sugar and phosphate

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11
Q

what holds the dna molecule together

A

hydrogen bonds

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12
Q

which are the nitrogen bases always connected to, the sugar or the phosphate

A

sugar

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13
Q

name the complementary strands of dna

A

adenine-thymine, cytosine-guanine

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14
Q

what enzyme unzips the 2 strands of dna in dna replication

A

dna helicase

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15
Q

what does dna polymerase do

A

link the compliments of the old dna strand together

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16
Q

what is mRNA

A

found in the nucleus, then moves thru nuclear pores to cytoplasm, single, uncoiled chain; carries genetic info of dna in the nucleus to the cytoplasm

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17
Q

tRNA

A

found in cytoplasm. Bonds to a specific amino acid and carries that amino acid to the ribosomes

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18
Q

rRNA

A

found in the ribosome(in cytoplasm), rRNA functions in the ribosomes as a metabolic molecule that aids in protein synthesis. (most common type, least understoood)

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19
Q

what are the 4 differences between dna and rna

A

Dna- 2 strands, deoxyribose(5-carbon sugar name), has thymine, stays in nucleus. Rna- 1 strand, ribose(5 carbon sugar name), uracil, can leave the nucleus

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20
Q

what is transcription and where does it occur

A

Rna molecules are produced by copying part of the nucleotide sequence of dna into a complementary sequence in rna; occurs in nucleus

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21
Q

step 1 of transcription

A

rna polymerase binds to a specific region of a dna molecule called the promoter site

22
Q

step 2 of transcription

A

Separation of complementary strands of dna occurs

23
Q

step 3 of transcription

A

Rna polymerase then uses one strand of dna as a template from which nucleotides are assembled into a strand rna

24
Q

step 4 of transcription

A

Rna polymerase reaches the termination site and the newly made rna is released

25
step 5 of transcription
The new rna strand moves from the nucleus to the cytoplasm though the nuclear pores. In the cytoplasm it will be read by a ribosome to make a protein
26
what enzyme is responsible for transcription
rna polymerase
27
how does mRNA move from the nucleus to the cytoplasm of a cell
it moves through nuclear pores
28
a series of 3 mRNA nitrogen bases that contain the info needed to make proteins are called what
codons
29
what is the universal start codon and what amino acid does it code for
AUG, methionine
30
what are the 3 stop codons
UGA, UAG, UAA
31
what is translation and where does it occur in the cell
The sequence of nitrogen bases in the newly made mRNA strand is translated into a chain of amino acids in the cytoplasm at the ribosome; occurs in the cytoplasm
32
step 1 of translation
mRNA made a copy of dna and then the mRNA exits the nucleus thru nuclear pores and enters the cytoplasm
33
step 2 of translation
tRNA is now activated to pick up a specific amino acid in the cytoplasm. tRNA transports the amino acid to the ribosome
34
step 3 of translation
When a tRNA anticodon binds to the mRNA codon, the amino acid it carries detaches from the tRNA and attaches to the end of a growing protein chain via peptide bonds
35
step 4 of translation
Once the a.a. has joined the protein chain, the tRNA detached from the mRNA strand
36
what does the word mutation mean
to change
37
mutations that produce changes in a single gene are called
gene mutations
38
mutations that produce changes in a whole chromosome are known as
chromosomal mutations
39
in what ways do most mutations affect organisms
most mutations have little to no affects
40
what are 3 examples of gene (point) mutations
substitution, insertion, and deletion
41
what does it mean that insertions and deletions usually result in a frameshift
A nitrogen base is added or taken away from the mrna strand which shifts the reading of the strand since the codons are read in 3s. So there would be a new grouping of 3s which shifts everything.
42
what are the 4 types of chromosomal mutations
translocation, inversion, deletion, and duplication
43
explain translocation
affects 2 different chromosomes, worst one, when one part of a chromosome breaks off and joins another
44
explain duplication
affects 1 chromosome, produces an extra copy of all or part of a chromosome, causes the original and duplication to cancel each other out
45
explain deletion
affects 1 chromosome, loss of all or part of a chromosome
46
explain inversion
affects 1 chromosome, switches parts of the chromosome right next to each other which changes the order of the original chromosome
47
what are the 3 types of substitutions
missense, nonsense, and silent
48
explain missense
if a substitution changes the amino acid
49
explain silent
if the substitution doesn't change the amino acid
50
explain nonsense
if the substitution changes the amino acid to a stop codon