biopsychology Flashcards

(16 cards)

1
Q

NERVOUS & ENDOCRINE SYSTEM
Ao1

A

**NERVOUS SYSTEM **
to collect/process/respond to information from environment & coordinate organs and cells

Central nervous system (CNS)
brain& spinal cord
* cerebral cortex allows higher functioning
* spinal cord allows info between brain & body; responsible for simple reflex actions/arcs

Peripheral nervous system (PNS)
Somatic nervous system
* controls voluntary movement & external environment, causes movement
* sensory receptors (to brain) and motor pathways

Autonomous nervous system:
controls involuntary body responses & internal environment
Sympathetic nervous system:
* responses to percieved threats, fight or flight
Parasympathetic nervou system:
* homeostasis, rest and digest function

ENDOCRINE SYSTEM
- works w/ nervous system to maintain homeostasis, peripheral NS collects info and sends signal to CNS for anything abnormal
- signal sent to endocrine glands to release hormones into bloodstrem. slower than nervous system but wider and more powerful effects

Main endocrine glands:
- PITUITARY (main): 6 hormones, FSH LH TSH ACTH GH PRL
- OVARIES, TESTES, THYROID, PANCREAS, ADRENAL

THE STRESS RESPONSE
- physical & psychological response to as stressor. adaptive as aids survival.
- hypothalamus triggers sympatheic nervous system & immediate f or f response dealt with by SAM system (sympatho adrenal medullary), releases adrenaline
-shuts down unnecessary functions, stimulates heart rate etc. parasympathetic restores once danger passes

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2
Q

NEURONS & SYNAPTIC TRANSMISSION
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STRUCTURE OF A NEURON
- Dendrite (recieves electrical impulses, makes it positively charged)
- Nucleus
- axon (transmits action potentials)
- nodes of ranvier (gaps allow jumping)
- myelin sheath (insulate nerve fibres)
- axon terminal (electrical signal triggers neurotransmitter release)

TYPE OF NEURON
- Motor neuron: nucleus in dendrites
-Relay neuron: nucleus in axon
-Sensory neuron: nucleus sticking out

SYNAPTIC TRANSMISSION
1. action potential travels down axon and reaches terminal on pre-synaptic neuron
2. triggers neurotransmitters to move to the membrane of neuron & be released into synaptic cleft
3. cross the cleft and bind to receptors on post synaptic neuron, triggering electric signal
4. neurotransmitters left in synapse are reabsorbed/broken down and vesticles are refilled

EXCITATION VS INHIBITION & SUMMATION
- excitory neurotransmitter messages make it more likely that post synaptic neuron wilkl fire (e.g. adrenaline)
- inhibitory neurotransmitters make it less likely (increase negative charge) e.g. serotonin
- neuron integrates excitory/inhibitory inputs and results in all or nothing effect, wether it will fire or not.

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3
Q

BIOLOGICAL RHYTHMS
Ao1

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patterns of changes in body activity in cyclical time periods. governed by exogenous zeitgebers/endogenous pacemakers

CIRCADIAN
- occur once every 24 hours, e.g. sleep wake cycle
- affected by sunlight and internal body clock (SCN), lies above optic chasm
Siffre cave study
- many periods of time living in caves in dark.
- 2 months in Alps, 6 months in Texas
- each time found his sleep/wake cycle defaulted back to 24-25 hours on a regular schedule. supports internal body clock
Folkard study
- pps lived in a cave for 3 weeks, went to bed and woke up at regular times by alarm clock.
- clock gradually sped up to 24 hours became 22
- natural biological rhythms were unable to adjustm, supports internal

core body temp cycle
varies by about 2 degreees C during day, lowest at 4am and highest at 6am. Folkard children who read stories 3pm = superior recall to at 9am.

INFRADIAN
takes longer, occurs less than once every 24 hours. for example menstrual cycle and SAD.
Menstrual cycle
- about 28 days, considerable variation
- rising oestrogen cause ovulation. progesterone thickens womb lining.
- no pregnancy = womb lining comes away.
McClintock
- wanted to test exogenous factors (other women’s hormones)
- 29 irregular period women, 9 gave pheromone samples
- pads rubbed against other pps each day
- found 68% experienced changes to cycle (closer)

Seasonal Affective disorder
-could also be ‘circannnual’.
-variation of mood, experience depression in the winter as daylight hours are shorter
-could be related to melanin production having knock on effect of reduced serotonin

ULTRADIAN
more than one cycle every 24 hours
Stages of sleep
- 5 distinct stages over roughly 90 mins
1. Light sleep , alpha waves, easily woken, muscles relax/twitch
2. also light & alpha waves or random changes to theta waves (sleep spindles). breathing, heart rate, temp fall
3&4. deep sleep, delta waves, all activity slows, difficult to wake
5. REM/dream sleep. body paralysed, brain active. theta waves

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4
Q

BIOLOGICAL RHYTHMS
Ao3

A

CIRCADIAN
STRENGTHS
- chronotheraputics - best time of day to deliver medicine, due to changes in body processes thoughout day. E.g. asprin late at night more effective for treating heart attacks than day
- understanding adverse effects of night shift work - experience reduced concentration around 6am, could cause accidents/mistakes (Boivin). Shift workers 3x more likely to develop heart disease due to disruptions
LIMITATIONS
- studies involves small numbers of pps, might not be representative. Schiffre body clock slowed with age, showing role of other factors
- individual differences - Czeisler found body clocks between 13-65 hours. Larks vs owls, and age factors. Averages may be meaningless.

ULTRADIAN
STRENGTHS

- led to phototherapy = one of most effective SAD treatments, strong lightbox in morning and evening thought to reset melatonin levels. Found improvement in 60% sufferers (Eastman).
- adaptive strategy of sycnchronised menstrual cycles, become pregnant as social group
LIMITATIONS
- Trevathan found no evidence of menstrual synchronisation. Many other factors affecting e.g. health, excersise, diet, stress.
-Tucker study found large differences in duration of sleep stages particularly 3&4. difficult to describe normal sleep in a meaningful way

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5
Q

EXOGENOUS ZEITGEBERS / ENDOGENOUS PACEMAKERS
Ao1

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end. p.makers - internal mechanisms that govern biological rhythms

suprachiasmatic nucleus
primary endogenous pacemaker in mammals
- nerve cells located in hypothalamus above optic chiasm
-recieves information about light, passes on to the pineal gland
- influences production of melatonin, chemical which induces sleep

Animal studies
Decoursey chipmunks
-destriyed SCN connections in chipmunks, returned to natural habitat and observed for 80 days
-sleepwake cycle had disappeared, many had been killed by predators, awake and vulnerable to attack at wrong times
Ralph hampsters
-bred mutant hampsters with 20 hour sleep wake cycle
-transplanted their SCN cells into normal hampsters
-their cycles defaulted to 20 hours

ex. z.gebers - environmental factors that influence biologicl rhythms
work trough entrainment - adjustment of body clocks in line with environment, become synchronised
- light is a key EZ, resets SCN.

Cambell & Murphy
-tested wether light could be detected by skin receptor sites on body, even when not recieved by eyes
-15pps woken at various times, light pads shone on backs of knees
-managed to produce deviation on s/w cycle of up to 3 hours

social cues
-babies adapt to parents sleep cycle in about 6 weeks

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6
Q

ENDOGENOUS PACEMAKERS / EXOGENOUS ZEITGEBERS
Ao3

A
  • total isolation cave studies very rare. IRL ex/en interact to set biological rhythms. makes little sense to separate them for research - could lower ecological validity
    -generalising animal studies to humans, plus harm to chipmunks
    -experience of people who experience different sunlight patterns to normal reduce effect of ex. zeitgebers - e.g. Arctic circle. have similar sleep patterns all year round
    -peripheral oscillators - numerous circadian rhythms that operate in cells/organs of the body. Damiola showed feeding patterns could change liver rhythms by 12 hours, despite SCN. more complicated factors.
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7
Q

LOCALISATION OF FUNCTION
Ao1

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-previous to 19th century holistic view of brain, then localisation. argued for by Brocca & Wernicke

Two hemispheres
-activity contralaterally wired
-cerebral cortex covers most of brain, much more developed in humans

Parts of brain
-frontal lobe (logic, planning, decisions, problems)
-parietal lobe (orientation, recognition, sensory info)
-temporal lobe (auditory info, speech analysis)
-occipital lobe (visual processing, back area visual cortex - eye info recieved)
-motor area (voluntary, fine motor movements)
-somatosensory (sensory info represented)

Brocca’s & Wernicke’s area
-Brocca’s area in left frontal lobe
-Brocca’s asphasia = can’t produce speech

-Wernicke’s area in left temporal lobe
-causes issues with speech comprehension

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8
Q

LOCALISATION OF FUNCTION
AO3

A

STRENGTHS
-Phinneas Gage - trauma to frontal lobe, changed personality and emotions. didn’t affect movement, speech, vision etc.
-Petersen brain scans - showed Brocca/Wernicke areas light up during reading/listening. modern scientific/objective evidence

LIMITATIONS
- Lashley’s rats - removed 10-50% of rats brains and taught maze. found no difference for specific area, learning too complex to be localised
-plasticity shows when area of brain damaged rest appears to reorganise to recover lost function. location not relevant

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9
Q

HEMISPHERIC LATERALISATION
AO1

A

idea that two halves of brain are functionally different.

Left and right hemisphere
- language localised to left (Brocca & Wernicke’s area)
- movement - not lateralised in general, but contralaterally wired.
- vision - not lateralised generally, contralaterally and ipsilaterally wired. all info from RVF goes to left hemisphere and vice versa.

Sperry
-study on 11 commissurotomy patients, had ‘separate’ brains, extent to which sides are specialised
- images / words projected to only one of the visual fields. pps focused on central cross
- when displayed to RVF could easily describe (left hem. responsible for language)
- when displayed to LVF couldn’t describe it, but could draw it or select with left hand
-tells us left hem. is verbal , right non verbal
-right processes emotions - racy images giggled, showing emotional response

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10
Q

HEMISPHERIC LATERALISATION
Ao1

A

STRENGTHS
- Fink PET scans during visual tasks. whole picture (holistically) right hemisphere, individual details (analysing) left hemisphere.
-Rogers found split brain chickens had better survival adaptations e.g. could find food & look for predators. adpative advantage
-Sperry study was highly scientific and standardised. Fixation point improved validity & lateralised pps.

LIMITATIONS
- lack of generalisability. only 11 and all had commissurotomies & epilepsy which could have caused further damage.

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11
Q

PLASTICITY & FUNCTIONAL RECOVERY
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plasticity = brain’s ability to adapt and change as a result of new learning.
growth spurt during infancy as well as synaptic pruning.
functional recovery = form of plasticity where brain can repair or redistribute functions to other areas

Maguire
-studied brains of taxi drivers who took ‘the knowledge’.
-used MRI scans and found significantly more grey matter in posterior hippocampus (spatial & navigational skills).
-more pronounced the longer they had the job.

processes in functional recovery
Never Sell A Dirty Rug
1. New synaptic connections made close to damage area
2. secondary neural pathways activated/unmasked to create similar functioning
3. axonal sprouting - grows new nerve endings which connect
4. denervation super sensitivity - remaining nerves become more sensitive to compensate
5. recruitment of homologous areas - similar opposite areas perform similar tasks

Jody
- showed functional recovery after trauma. due to epilepsy entire right hemisphere was removed
- within 10 days could walk, slight paralysis in left side but improved significantly over time.
-left side developed and adapted to take over role.

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12
Q

FUNCTIONAL RECOVERY
Ao3

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STRENGTHS
-practical application - has led to development of neurorehabilitation. e.g. constraint induced movement therapy for stroke patients, limb strapped down
- Bezzola golf study, pps aged 40-60. 40 hours of golf training, found increased motor cortex activity. shows not limited to young brains
-Hubel & Wiesel sewed kittens’ eyes shut. Inactive part of brain refocused & processed info from other eye

LIMITATIONS
- correlation vs causation of the knowledge.
- phantom limb syndrome - 60-80% of amputees suffer, due to reorganisation of somatosensory area.

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13
Q

Studying brain - fMRIs

A

Ao1:
-functional magnetic resonance imaging
- uses magnets to determine haemoglobin (blood flow) to different areas.
- increased demand for oxygen whilst completing certain tasks in certain areas
- able to produce maps of areas used in certain functions

Ao3:
STRENGTHS
- doesn’t rely on radioactive tracer, risk free & non invasive
- produces high resolution images, accurate to the mm. clear images of localised functions

LIMITATIONS
- expensive machines, specially trained experts to operate
- temporal resolution - indirect measure, studying blood flow not firing - 5 second delay

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14
Q

ways of studying the brain - EEG

A

Ao1:
electroencephalogram
- measures electrical activity in brain through electrodes placed on scalp
- can be used to detect types of brain disorder (e.g. Alzheimers / epilepsy)
- diagnostic tool to recognise abnormalities

Ao3:
STRENGTHS
- useful/practical for making diagnoses, RWA
- high temporal resolution (can detect firing in milliseconds)
LIMITATIONS
- general measure of groups of neurons/areas. not specific locations
- doesn’t allow differentiation between different but adjacent areas

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15
Q

ways of studying brain - ERPs

A

Ao1
event related potentials
- EEGs too crude / general in raw form, way of isolating responses using statistical averaging, extraneous activity filtered out
- brainwaves left that are triggered by certain events. how these are linked to perception/cognition

Ao3:
STRENGTHS
- more specific than raw EEG
- excellent temporal resolution

LIMITATIONS
- differing procedures adopted by different institutions, not standardised
- all extraneous variables must be eliminated for it to work

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16
Q

ways to study the brain - post mortems

A

Ao1
- used to establish underlying neurobiology of brain / particular behaviour
- when someone displays interesting behaviour whilst alive, can later study brain abnormalities
- e.g. Brocca

Ao3
STRENGTH
-improve medical knowledge, vital in early days of psyschology before technology
LIMITATION
- doesn’t allow for study of functional activity