Biorisk Management Flashcards
(22 cards)
Risk associated to biological toxins or infectious agents
Biorisk
Likelihood of biological exposure vs. Severity of consequences; process of determining how effective certain risk control measures are against them
Risk Evaluation
Integration of biosafety and biosecurity when handling biorisks
Biorisk Management
Who defined biorisk management as “a system to control safety and security risks associated with the handling of biological agents in laboratory facilities”
CEN Workshop Agreement 15973
Three primary components of Biorisk Management
Assessment, Mitigation, and Performance
The model being compared to a three-legged stool where if one component is lacking, the whole system will fail to operate optimally
AMP Model
Process of identifying hazards and characterizing risks possibly present in the laboratory; aka the HEART of BRM
Risk Assessment
Anything in the environment that has the potential to cause harm
Hazard
The possibility that an adverse effect will happen with respect to the presence of a hazard
Risk
A step in the risk assessment process that refers to identifying hazards, risks, exposed subjects, work activities, location, procedures, and equipment within the scope of the laboratory work
“Define the situation”
A step in the risk assessment process that refers to identifying how certain laboratory risks can cause harm to the subjects exposed to the laboratory work
“Define the risks”
A step in the risk assessment process that refers to comparing the likelihood and consequences of the biological risks present in the laboratory; can be either through qualitative or quantitative data
“Characterize the risks”
A step in the risk assessment process that refers to deciding whether or not the established risk control programs are adequate enough to prevent any hazards from harming the subjects
“Determine if risks are acceptable or not”
These are measures that are put into place to reduce or eliminate the risks that come with handling biological agents
Mitigation Procedure
The most difficult yet most effective control measure that completely removes any involvement with the biological agent
Elimination
The process of replacing dangerous biological agents with a more manageable and safer yet similar sample
Substitution
Involves changing the physical conditions of the laboratory to prevent exposure to hazards
Engineering Controls
Refers to policies implemented to control the risks that come with handling biological agents in the laboratory; implemented by the higher-ups that manage the laboratory
Administrative controls
SOP stands for?
Standard Operating Procedures
Refers to the process of wearing garments and devices that protect laboratory workers from the threat of laboratory hazards; it is the easiest to implement yet the most ineffective one
Wearing of PPE
Involves following a systematic cycle of continuously checking and evaluating laboratory operation to achieve organizational objectives
Performance Evaluation
Refers to the reevaluation of the overall mitigation strategies
Performance Management
