Bipolar disorders Flashcards

1
Q

what things can be included in the presentation of pressured speech

A

puns, jokes, rhymes, or plays on words

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2
Q

what are common misdiagnoses for mania in adolescents

A

conduct disorder
antisocial personality disorder
schizophrenia

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3
Q

9 possible mania symptoms in adolescents

A

psychosis
substance use
suicide attempts
academic problems
philosophical brooding
OCD symptoms
multiple somatic complaints
marked irritability causing fights
antisocial behavior

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4
Q

when are multiple manic episodes considered distinct

A

when they are separated by at least 2 months

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5
Q

what is considered rapid cycling

A

at least 4 mood episodes in a year

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6
Q

cyclothymia

A

period of at least 2 years of hypomanic and depressive episodes that cause clinically significant distress but do not meet full criteria for bipolar disorder

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7
Q

what is hypomania frequently confused with

A

borderline personality disorder

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8
Q

poor prognosis predictors for bipolar disorder

A

poor ocupational status
alcohol dependence
psychotic features
depressive features
male gender

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9
Q

better prognosis predictors in bipolar disorder

A

short duration of mania
advanced age at onset
few suicidal thoughts
fewer comorbidities

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10
Q

what are the most common psychological deficits in bipolar disorder

A

executive function
verbal memory/reasoning

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11
Q

bipolar with seasonal pattern

A

may have winter depression or spring mania

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12
Q

anticonvulsants typically used for bipolar

A

lamotrigine
carbamazepine
valproate

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13
Q

therapeutic lithium levels

A

0.6-1.2

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14
Q

medication classes used to treat acute mania

A

lithium
anticonvulsants
antipsychotics

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15
Q

medication classes for treatment of acute bipolar depression

A

anticonvulsants
antipsychotics
antidepressants
ECT
Lithium

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16
Q

which anticonvulsant is most frequently used for bipolar depression

A

lamotrigine

17
Q

which medications are highly associated with mania induction

A

TCAs
MAOIs
venlafaxine

18
Q

therapy options for treating bipolar

A

CBT
interpersonal
social rhythm
family

19
Q

mood episode commonality between the sexes

A

depressive episodes more common in women
manic episodes more common in men

20
Q

therapeutic blood level for depakote

A

50-120

21
Q

first line anticonvulsant treatment for acute mania in bipolar

A

valproate and carbamazepine

22
Q

lamotrigine in bipolar

A

better at treating bipolar depression than mania

23
Q

what is valproate approved for in bipolar

A

acute mania, not maintenance

24
Q

important thing to remember about starting lamotrigine

A

must be titrated slowly to avoid rash

25
Q

which antipsychotic has the best evidence for treatment of acute bipolar depression

A

seroquel

26
Q

administration of antidepressants in bipolar

A

needs to be in conjunction with mood stabilizer to avoid induction of mania

27
Q

most widely used agents for long term treatment of bipolar

A

lithium
valproate
carbamazepine

28
Q

what is often required with long term lithium treatment

A

thyroid supplementation

29
Q

what to do for first-line treatment failures

A

try another first-line treatment option

30
Q

goals for therapy with bipolar disorder

A

improving treatment adherence
promoting stability
avoiding risk factors

31
Q

what inflammatory markers are typically elevated in bipolar patients

A

interleukin-6

32
Q

response inhibition

A

executive function that allows one to control impulsive responses when they might be inappropriate