Bitter Principles Flashcards

1
Q

Uncetain chemicals of bitter principles?

A

Picrotoxin, colocynthin, quassin

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2
Q

Abundant bitter principles?
Compositae?
Labiatae?
Gentianaceae?

A

All of them

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3
Q

Phenolic bitter principles family?
Rutaceae or cannabinaceae?

A

Cannabinaceae

Humulus lupulus cannabinaceae

Humulone + lupulone

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4
Q

What is used in the preparation of beer? Belongs to which bitter principle

A

Hops, Phenolic bitter principle

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5
Q

Alcoholic soln. Humulone + Fecl3 —> ??

A

Reddish violet

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6
Q

Santonin belongs to lactone or coumarin bitter principles?
Its family?

A

Lactone

Compositae

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7
Q

% of santonin and artemisin

A

2-3.5% of santonin and artemisin

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8
Q

Santonin + NaOH —> ??

A

Violet red changes to reddish yellow

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9
Q

Santonin + ?? + h2o —> no colour , + fecl3 —> violet

A

H2so4

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10
Q

Khellin is a chromone bitter principle, its S.N?

A

Ammi Visnaga Umbellifera

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11
Q

Ammi visnaga umbellifera refers to chromone or coumarone?

A

Chromone

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12
Q

Khellin + ?? —> rose red

A

KOH

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13
Q

Khellin + tannic acid. —> ??

A

Faint ppt.

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14
Q

Uses: coronary vasodilator + bronchodilator

Bitter principle ?S.N ?

A

Chromone, ammi visnaga

Khellin

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15
Q

Xanthotoxin (ammoidin) is coumarone or coumarin?

A

Coumarin

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16
Q

Ammi majus (family?)
Ruta gravelolens (family?)
Fragara xanthoxyloides (family?)

Coumarone or coumarin?

A

Umbelliferae
Rotaceae
Umbelliferae

Coumarins of xanthotoxin

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17
Q

Xanthotoxin + h2so4 —>
Xanthotoxin + froehd’s reagemt —>

A

Orange yellow

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18
Q

Which reagent gives orange yellow —> light green when reacting with xanthotoxin?

A

H2SO4

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19
Q

Which reagent gives orange yellow —> dirty green when reacting with xanthotoxin?

A

Froehd’s reagent

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20
Q

Used for leukodermia?

A

Xanthotoxin (ammoidin) , coumarin bitter principle

Ammi majus umbelliferae
Fragara xanthoxyloides umbelliferae

Ruta gravelolens rutaceae

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21
Q

Coumarone bitter principles ? Xanthotoxin - khellin - rotenone?

A

Rotenone

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22
Q

Derris elleptica, derris malacecensis! Lonchocqrpus utilis refer to family? (Liliaceae or leguminosae)?

A

Leguminosae

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23
Q

Preparation pf coumarone, rotenone
Powder + ?? In Soxhlet

A

Ccl4

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24
Q

Preparation pf coumarone, rotenone

Rotenone+ acetone + 50% HNO3 giving what colour ? Red - Blue - violet?

A

Blue

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25
What compound is known as climbing shrub?
Picrotoxin [Anamirta cocculus Menispermaceae]
26
Menispermaceae belongs to ( picrotoxin or quassin)?
Picrotixin
27
A. Picrotoxin + H2SO4 giving what colour? B. Pictotoxin + H2SO4 react with what to give blue colour? C. Picrotixn +?? —> green colour
A. Golden yellow turns to reddish brown B. Anisaldehyde C. Vanillin hydrochloride
28
What is used as antidote ( barbiturates poisoning)?
Picrotoxin ( anamirta cocculus Menispermaceae)
29
What is known to be as insecticide and anthelmintic? Picrotixin or quassin?
Quassin Picrotixn: as antidote for barbiturate poisoning
30
Simaroubaceae for quassin or pyrethrum?
Quassin
31
Quassin+ sucrose + h2so4 —> red or violet?
Red
32
Quassin + phloroglucin + hcl —> violet or crimson colour? All red colour of quassin test
Crimson colour (red)
33
Sponge Tethya crypta is Ara-A (1) or avarol (4)
Ara-A (1)
34
Is ara-A 1 semi synthetic (yes / No)
Yes. Its semi synthetic
35
Sponge Disidea avarea represents ( Ara-A (1) or Avarol (4) & (5)). ?
Avarol (4) & (5)
36
Ara-A (1) and avarol (4) & (5) are: A. Cytotoxin B. Antiparasitic C. Anticoagulant D. Antiviral
D. Antiviral
37
A- kainic acid is : A. Cytotoxin B. Antiparasitic C. Anticoagulant D. Antiviral E. Antimicrobial
B. Antiparasitic
38
Domic acid is : A. Cytotoxin B. Antiparasitic C. Anticoagulant D. Antiviral
B. Antiparasitic
39
Nereistoxin is: A. Cytotoxin B. Agrochemical C. Anticoagulant D. Antiviral
B. Agrochemical
40
Which one of these compounds represents sea hare: A. Cytotoxin B. Antiparasitic C. Anticoagulant D. Antiviral
A. Cytotoxin
41
Dolastatin represents cytotoxin compound What is its S.N?
Dolabella auricularia
42
Chondria armata represents (a- kainic acid or domic acid) ? Which group (antiparasitic or anticoagulant)?
Domic acid Antiparasitic
43
Brown algae belongs to : A. Cytotoxin B. Antiparasitic C. Anticoagulant D. Antiviral
C. Anticoagulant
44
Fucoidan is known as ? ( green - red - brown ) algae Antimicrobial or anticoagulant
Brown algae Anticoagulant
45
Fucus vesiculosus represents ? A. Cytotoxin B. Antiparasitic C. Anticoagulant D. Antiviral
C. Anticoagulant - fucoidan - brown algae
46
Cephalosporin C and cephalothin sodium ( semi- synthetic) ? A. Cytotoxin B. Antiparasitic C. Anticoagulant D. Antimicrobial
D. Antimicrobial
47
Soft coral ( plexaura homomalla ) belongs to: A. Cytotoxin B. Prostaglandin C. Agrochemical D. Antiviral
B. Prostaglandin
48
Nereisoxin S.N? Hint: Lumb hetero.dopa
Lumbriconeris heterpdopa
49
Used as rapid anesthetic on insect, toxic to fish & mammals? A. Antimicrobial B. Antiparasitic C. Agrochemical D. Antiviral
C. Agrochemical
50
Saxitoxin & neosaxitoxin are examples of ( paralytic or diarrhetic ) shellfish poison ?
Paralytic shellfish poison
51
Dinophysistoxin-1 is an example of (paralytic / diarrhetic ) shellfish poison?
Diarrhetic
52
All of the following are synptoms of shellfish poisoning except? Nausea Vomiting Anorexia Diarrhea Loss of long-term memory Gastric bleeding comma Andominal cramps
Loss of long-term memory
53
Which has the following function. (Saxitoxin - neosaxitoxin - tetrodoxin - dinophysistoxin -1) Relaxing smooth muscle spasm
Tetrodoxin
54
Fish livers as a source of vitamin x and x? A & B B &C A & C C & D A & D B & C
A & D
55
Pyrethrum flower family? A. Moraceae B. Cannabinaceae C. Compositae D. Liliaceae
Compositae
56
Pyrethrum flower Chrys.. ciner.. Tan.. ciner.. Pyrethrum ciner All are related to ( Compositae )
Also used as insecticide
57
Pyrethrin percentage? A. 35% B. 15% C. 25% D. 45%
C. 25%
58
Indian hemp family name?
Moraceae / cannabinaceae
59
Enhance THC activity, antifungal, antibacterial, anti-inflammatory? Cannabidiol or cannabichronene
Cannabichromene
60
Cannabidiol is: A. Antibacterial B. Antifungal C. Anti-imflammatory D. Anticoagulant E. Anticonvulsant
E. Anticonvulsant
61
Cannabidiol is anticonvulsant, alongside it is?
Analgesic
62
Delta-9 THC USED TO:?
Relief nausea and vomining caused by chemotherapy
63
To stimulate the appetitie of aids patients, which country? A. In the USA B. In the UK C In Asia
A. In the USA
64
Dronabinol
In the UK
65
Lophophora williamsii represents? A. Podhyllium B. Peyote C catharanthus
B. Peyote
66
Ingestion of peyotes results in 1- mydriasis 2. Bizarrencolour 3 flashing lights Then becomes dim, drowsy
67
Tumor inhibitor? A. Ginseng B. Podophyllum C. Peyote
B. Podophyllum
68
What parts of podophyllum are used for medicinal purpose? A. Leaves and stems B. Rhizome and roots C. Barks D. Flowers E. Seeds
B. Rhizome and roots
69
The main active component of Podophyllum? A. Flavonoid B. Terpene C. Resin D. Alkaloid
C. Resin
70
American podophyllum yields?
2-8%
71
Indian Podophyllum yields?
6-12%
72
Desoxypodophyllotoxin, podophyllotoxone are ? Cytotoxic? Yes or no? Posses Antitumor activity ? Yes or no?
Yes
73
Traditional use of podophyllum resin? A. Treatment of lung cancer B. Treatment of leukaemia C. Treatment of watrs
C. Treatment of warts
74
What compound is obtained from podophyllotoxin?
Etoposide
75
A. Podophyllum hexandrum berberidaceae - Indian or american? B. Podophyllum peltatum berberidaceae - Indian or american?
A. Indin B. American
76
Catharanthus roseus is a root or sub-shrub?
Sub-shrub
77
Catharanthus.. Sub- shrub , belongs to family?
Apocynaceae
78
How many alkaloids are found in catharanthus roseus? A. 60 B. 100 C. 70 D. 150
D. 150
79
The percentage of vincristine is? L euro ( vincrostine) Vinca uk (vinblastine)
0,0002%
80
Hodgkin’s disease is treated by? A. Vindesine B. Viblastine C. Vincristine D. Vinoelbine
B. Vinblastine
81
Lung, cervical, breast cancer are related to? A. Vinblastine B. Vindesine C. Vincristine
C. Vincristine
82
Vincristine has ( acute ) lymphatic leukemia. Which also has the same?
Vindesine
83
S.N of plant associated with taxol? A. Taxus brevifolia B. Taxus canadensis C. Taxus buccata D. Taxus cuspidata
A. Taxus brevifolia
84
Diterpenoid derivatives “ taxanes” are constituents of taxol (yes / no)?
Yes
85
Taxotere can be used for ovarian cancer (true / false)?
False Taxol —for ovarian cancer+ breast cancer Taxotere — for breast cancer onnnnnly
86
Pacl. Taxol Doc. Taxotere
Paclitaxel (taxol) Docetaxel (taxotere)
87
Taxol isolated in ? A. 1961 B. 1959 C. 1971 D. 1951
C. 1971