Phto Slide 43 Flashcards

(67 cards)

1
Q

Tropane alkaloids belongs to families?

A

Solanaceae
Discoreaceae
Erythroxylaceae
Convolvulaceae

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2
Q

How is Atropine primary formed ?

A

From hyoscymine

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3
Q

What is the m.P. of atropine?

A

118

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4
Q

Atropine is commonly obtained from?

A

Atropa belladonna

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5
Q

What is the most widely distributed alkaloid?

A

Hyoscyamine

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6
Q

What is the primary use of scopolamine?

A

Antispasmodic

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7
Q

What effect does scopolamine has on CNS?

A

Stimulate CNS

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8
Q

What is the sequence of the effect that atropine has on CNS?

A

Stimulation followed by depression or paralysis

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9
Q

Stramonium S.N?

A

Datura stramonium

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10
Q

Family of stramonium?

A

Solanaceae

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11
Q

Percentage range of alkaloids present in stramonium?

A

0.2 - 0.45%

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12
Q

% of Alkaloids found in seeds of Datura stramonium?

A

0.2%

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13
Q

Hyoscine hydrobromide used as?

A

Sedative

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14
Q

Which are used in ophthalmic practice to dilate the pupils?

A

Atropine
Hyoscine

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15
Q

Hyosciamus niger. Family?

A

Solanaceae

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16
Q

Egyptian henbane S.N?

A

Hyoscyamus muticus

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17
Q

(Egyptian hehbane) Hyoscyamus muticus belongs to the family?

A

Solanaceae

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18
Q

Principal alkaloids of hyoscamus leaf (hyoscyamus niger solanaceae)

A

Hyoscyamine and hyoscine

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19
Q

Which leaf resembles belladonna and stramonium, but weaker?

A

Hyoscyamus niger solanaceae (hyoscyamus leaf)

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20
Q

What is the principal alkaloid in hyoscamus muticus solanaceae (egyptian henbane)?

A

Hyoscyamine

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21
Q

What is the chief alkaloid of atropa belladonna solanaceae?

A

Hyoscyamine

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22
Q

% of alkaloid content range in the leaves of atropa belladonna?

A

0.3 - 0.6%

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23
Q

Mandrake S.N?

A

Mandragora officinarum solanaceae
Mandragora autumnalis solanaceae

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24
Q

Roots of madrake contains?

A

AASMH

ATROPINE
SCOPOLETIN
SCOPOLAMINE
MANDRAGORINE
HYOSCYAMINE

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25
Cocaine, cinnamyl cocaine b-truxilline are derivatives of ?
Derivatives of ecgonine
26
Tropacocaine and valerine are derivatives of?
Derivatvies of pseudotropine
27
Hygrine and cuscohygrine are derivatives of?
Derivatives of pyrrolidine
28
Tropine 2-carboxylic acid ?
Ecgonine
29
Benzoylecgonine methyl ester respresents ecgonine or cocaine?
Cocaine
30
Prep of cocaine Lime or sodium carbonate —> through ?
Petroleum ether
31
Cocaine + 5% gold chloride —> ??
Stellate rods
32
Cocaine + platinic chloride —> ??
Yellow needles
33
Coca leaf family?
Erythroxylaceae
34
Brompton’s cocktail control pain of terminal cancer and is treated by cocaine HCL
Cocaine HCL
35
Alkaloids of quinoline groups?
Cinchona bark Quinine
36
Cinchona bark S.N?
Cinchona ledgeriana rubiaceae Cinchona succirubra rubiaceae
37
Quinine is L or D Quinidine is L or D
Quinine (L) Quinidine (D)
38
Cinchonine is L or D? Cinchonidine is L or D?
Cinchonine (D) Cinchonidine (L)
39
Treatment of malaria?
Quinine
40
Prophylaxis of cardiac arrhythmia + treatment of atrial fibrillation by? + antimalarial
Quinidine
41
R = OCH3 is for (quinine & quinidine) or (Cinchonine & Cinchonidine)
(quinine & quinidine)
42
R= -H is for (quinine & quinidine) or ( cinchonine & Cinchonidine)
(cinchonine & Cinchonidine)
43
Quinine is heated with potassium hydroxide KOH in amyl alcohol producing?
Quinidine
44
Herpathite test: Quinine + galcial acid + %% alcohol + h2so4 —> iodosulfate of quinine What is the percentage of alcohol?
90% alcohol
45
Alkaloids of isoquinoline are? BC I OH
Bloodroot Curar Ipecacuanha Opium Hydrastis
46
Alkaloids of iso quinoline?
Ipecacuanha Curar Opium Bloodroot Hydrastis
47
Ipecacuanha S.N?
Cephaelis Ipecacuanha rubiaceae
48
Cephaelis ipecacuanha rubiaceae alkaloid content %?
2 - 2.5%
49
Emetine and cephaeline are contents of?
Ipecacuanha ( cephaelis ipecacuanha rubiacea)
50
Emetic + exceptorant + amoebic dystentery are used by?
Ipecacuanha
51
Cephaeline methylation —> ??
Emetine
52
What compound is Readily soluble in alcohol, ether, chloroform? But sparingly soluble in water
Emetine
53
What compound that is readily soluble in alcohol, chloroform But insoluble in water.
Cephaeline
54
Emetine and cephaeline + froehd’s reagent —>??
Greenish yellow
55
Curare families? Logan Men is per mac
Loganiaceae Menispermaceae
56
Curare Loganiaceae S.N?
Strychnos toxifera
57
Curare Menispermaceae S.N?
Chondodendron tomentosum
58
What is used as muscle relaxant in surgical operation / neurological conditions?
Tubocurarine chloride
59
Tubocurarine chloride + FeCl3 ferric chloride —> ?
Green colour
60
D-tubocurarine chloride + sodium carbonate —> ??
Yellow brown
61
?? + sodium carbonate. —> yellow browm
D-tubocurarine chloride
62
Opium poppy S.N?
Papaver somniferum paparveraceae
63
Opium poppy not less than %% morphine?
10%
64
% of codeine in opium?
2%
65
P. Somniferum var glabrum Country? Colour?
Turkey Purplish - white
66
P. Somniferum var album Country? Colour?
India White
67
P. Somniferum var nigrum Country? Colour?
Europe Violet