Blisters Flashcards
(63 cards)
1
Q
what is the difference between a vesicle and a bulla
A
- diameter
2
Q
what distinguishes erosion from ulcer
A
- depth
3
Q
what is the name for a small blister
A
- vesicle
4
Q
what is the name for a large blister
A
- bulla
5
Q
what is the name for when blisters unroof
A
- erosion
6
Q
what is the name for dried transudate
A
- crust
7
Q
what does acral mean
A
- on distal extremities - hands and feet
8
Q
what does arcuate mean
A
- in an arc or curve
9
Q
what does dermatomal mean
A
- follows distribution of sensory nerve
10
Q
what does intertriginous mean
A
- in the body’s folds
11
Q
what does linear mean
A
- straight line
12
Q
_____ is caused by an eruption of latent varicella zoster virus
A
- herpes zoster
13
Q
group vesicles on an erythematous base are typical of
A
- herpes zoster
14
Q
herpes zoster is usually preceded by
A
- pain or burning
15
Q
shingles in the immunocompetent versus HSV
A
- shingles occurs once - HSV recurs
16
Q
treatment for shingles
A
- acyclovir - valacylovir
17
Q
clues to diagnosis of shingles
A
- dermatomal eruption - unilateral distribution
18
Q
grouped vesicles on an erythematous base on the chin and lip are most likely
A
- herpes simplex
19
Q
what do the vesicles of herpes simplex look like
A
- pustular
20
Q
HSV1 favors what regions
A
- mouth and nose
21
Q
HSV2 favors what regions
A
- genitalia - buttock - thighs
22
Q
perianal erosions or ulcerations in the immunosuppressed patients are usually _____
A
- herpes simplex
23
Q
recurrent ulcers on buttocks or genitals are _____ until proven otherwise
A
- HSV
24
Q
what is herpetic whitlow
A
- form of herpes on the finger
25
what is Tzanck prep problems
- scrape and microscopic exam - can't differentiate VZV from HSV
26
viral culture for HSV can be performed when ____ is present
- fluid
27
\_\_\_\_\_ can differentiate HSV 1 and 2 as well as VZV
- direct fluorescent antibody test
28
\_\_\_\_\_\_\_\_\_ determines past exposure but may not directly relate to clinical findings
- HSV antibody detection
29
\_\_\_\_\_\_\_\_\_ is a rapid and sensitive diagnostic test that differentiates HSV1, HSV2, and VZV and is the initial test of choice at UNC
- fluid swab
30
treatment for HSV
- acyclovir
31
why don't we use famciclovir or valacyclovir for HSV treatment their benefit
- more expensive - easier dosing
32
what presents as very pruritic vesiculopapules on the palms, soles, and sides of the fingers
- dyshidrotic eczema
33
after healing, dyshidrotic eczema leave behind a mark with a _______ color called \_\_\_\_\_\_\_\_
- mahogany color - post-inflammatory hyperpigmentation
34
mainstay of treatment of dyshidrotic eczema
- potent topical steroids
35
what conditions have vesicles located on the dorsal foot
- contact dermatitis - insect bites
36
what conditions have vesicles located on the sides of feet and toes
- dyshidrotic eczema
37
what conditions have vesicles located on the soles
- tinea pedis
38
what conditions have vesicles located on the balls, heels of foot
- friction blisters
39
what conditions have vesicles located on the mouth/nose/eyes
- HSV - bullae impetigo
40
what conditions have vesicles located on the chest and back in a dermatomal pattern
- VZV
41
what conditions have vesicles located on the fingers
- dyshidrotic eczema - contact dermatitis - herpetic whitlow
42
what conditions have vesicles located on the arms and legs
- contact dermatitis
43
what conditions have vesicles located on the genitalia with a bathing suit distribution
- HSV
44
what conditions have vesicles located on the feet
- dyshidrotic eczema - tinea pedis - allergic contact dermatitis
45
in which conditions does pain precede onset
- HSV - VZV
46
in which conditions does itch precede onset
- allergic contact dermatitis - dyshidrotic eczema - VZV
47
in which conditions does trauma precede onset
- friction blister - pressure ulcer - cryotherapy
48
in which conditions do you have recurrent blisters
- HSV
49
what is the primary VZV infection
- chicken pox
50
buzzword condition for diffuse vesicles on an erythematous base with various stages of healing
- chicken pox
51
how to diagnose chicken pox
- PCR - DFA - cultura - Tzank
52
in pemphigus vulgaris, you have autoantibodies to _________ between keratinocytes resulting in ______ bullae and erosions
- desmogleins 1 and 3 - superficial
53
pemphigus vulgaris is usually seen in which age group
- elderly
54
pemphigus vulgaris diagnose by
- directly immunofluorescence
55
pemphigus vulgaris classically has _____ involvement
- oral
56
autoantibodies to desmoglein 3 and 1 in pemphigus vulgaris form what pattern
- net-like
57
bullous pemphigoid, you have autoantibodies to _____ resulting in _______ bullae on pruritic, urticarial base
- hemidesmosome - deep, tense
58
bullous pemphigoid split between which two layers
- basement membrane and basal layer
59
bullous pemphigoid affects what age
- elderly
60
bullous pemphigoid which antibodies found with direct immunofluorescence
- BPAG2 antibodies
61
bullous pemphigoid has what pattern of staining at the basement membrane zone
- linear staining
62
when would you do a biopsy for direct immunofluorescence test
- autoimmune bullous diseases
63
bullous impetigo can be diagnosed with
- bacterial culture
