Block 3 Anesthetics Flashcards Preview

Pharmacology > Block 3 Anesthetics > Flashcards

Flashcards in Block 3 Anesthetics Deck (17)
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1
Q

Halothane (Inhaled)

A

MOA: interact with neuronal membrane inhibit ion influx
LOW MAC VALUE
High B/G, met by liver
SE: 3 H’s

2
Q

Isoflurane (Inhaled)

A

High B/G
SE: bronchocon & inc bronchiolar sensitivity
CI: asthma

3
Q

Desflurane (Inhaled)

A

Low B/G SE: airway irritation

4
Q

Sevoflurane (Inhaled)

A

Low B/G, safe in asthma, CI: kidney dysfxn

5
Q

Enflurane (Inhaled)

A

muscle spasms

6
Q

N2O

A
MOA: nitrous oxide
does NOT cause sk ms relax 
HIGH MAC value
LOW B/G
"laughing gas"
SE: diffusional hypoxia, can cause abortion in pregnancy
7
Q

Thiopental (IV)

A

Barbiturate
very lipid soluble
OD: resp & cvs depression
OD Rx: urine alk

8
Q

Midazolam (IV)

A

Benzo
Causes sk ms relax
OD: resp & cns depression
OD Rx: IV Flumazenil (BZ receptor ant)

9
Q

Fentanyl (IV)

A

Opioid
has analgesic fx
OD: resp depression, miosis, constipation
OD Rx: Naloxone (Opioid reception ant)

10
Q

Propofol (IV)

A

“Milk of Amnesia”
anti-emetic fx
rapid onset&recovery
out-pt surgeries

11
Q

Ketamine (IV)

A
PCP analog
MOA: NMDA ant
only anesthetic to cause CVS stimulation
causes: amnesia, analgesic, cataplexy
decreases pain perception
12
Q

Cocaine, Procaine, Chloroprocaine (Local) (Esters)

A

MOA: Na+ channel blocker
shorter duration
met by esterase in plasma

13
Q

Lidocaine, Bupivacaine, Mepivacaine (Local) (Amides)

A

Greater analgesic prop
longer duration
met by amidases in liver

14
Q

Tetrodotoxin

A

Puffer fish; MOA: blocks ACTivated Na channels

15
Q

Saxitoxin

A

dinoflagellates in red tide; blocks ACTivated Na channels

16
Q

Ciguatoxin

A

exotic fish; bind to ACTivated Na channels keeping them open

17
Q

Batrachotoxin

A

south american frogs; bind to activated Na channels keeping them open