Blocks/ Epidurals/ Pain Management Flashcards

(91 cards)

1
Q

Blocks/ Epidurals/ Pain Management

What are opioids/ narcotics?

A

Binds to Mu, Delta, Kappa receptor sites to produce morphine like or opioid agonist effect by acting on pain modulating system. Can be natural or synthetic.

Caution: watch out for respiratory depression.

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2
Q

Blocks/ Epidurals/ Pain Management

What is morphine?

A

Prototype for strength of other narcotics
Can cause histamine release
Can cause spasm of biliary smooth muscle
Useful in treatment of angina in ACS
Peak effect in 20 minutes

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3
Q

Blocks/ Epidurals/ Pain Management

Morphine facts

A

Route IV
Dose 2-15mg
Onset < 1 minute
Peak 20 minutes
Duration 2-7 hours

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4
Q

Blocks/ Epidurals/ Pain Management

What is hydromorphone?

A

6x more potent than morphine
Recommended in renal patients d/t lack of active metabolites after broken down in the liver

Can be administered spinal / epidural due to high lipid solubility

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5
Q

Blocks/ Epidurals/ Pain Management

Hydromorphone facts

A

Dose 0.5 - 2mg IV
Onset < 60 sec
Peak 5 - 20 min
Duration 2 - 4 hrs

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6
Q

Blocks/ Epidurals/ Pain Management

What is fentanyl?

A

100x more potent than morphine
Can cause fixed chest syndrome

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7
Q

Blocks/ Epidurals/ Pain Management

Fentanyl facts

A

Dose 0.05 - 2mcg/kg IV
Onset < 30 sec
Peak 3 - 7 min
Duration 30 - 60 min

Monitor patient for respiratory depression for at least 1 hour after admission to PACU

Note that fentanly is administered as weight based.

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8
Q

Blocks/ Epidurals/ Pain Management

What is fixed chest syndrome?

A

Can be caused by rapid IV injection of Fentanyl
Leads to bronchial constriction and resistance to ventilation, rigidity of diaphragmatic and intercostal muscles.
Reversal - administer subclinical dose of succinylcholine (w/c will relieve rigidity of chest wall?)
Additional action - Ventilate

Succinylcholine is a non depolarizing muscle relaxant.

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9
Q

Blocks/ Epidurals/ Pain Management

What is Meperidine?

A

1/10x as potent as morphine
Primary for post operative shivering
Not commonly used for pain

Contraindications
a. Use of MAOIs - d/t resp depression w/ concurrent use of meperidine
b. potentiates seizure because of toxic metabolite (normeperidine) that lowers seizure threshold and induce CNS excitability

Trivia - meperidine is chemically smilar to atropine

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10
Q

Blocks/ Epidurals/ Pain Management

What are commonly prescribed MAOIs?

A

Selegiline
Isocarboxazid
Phenelzine
Tranylcypromine

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11
Q

Blocks/ Epidurals/ Pain Management

Meperidine facts

A

Dose 12.5 - 25 mg
Onset 1 - 3 min
Peak 5 - 20 min
Duration 2 - 4 hrs

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12
Q

Blocks/ Epidurals/ Pain Management

What is opioid overdose treatment?

A

Naloxone
0.2 - 0.4mg reverses respiratory depression
Titrate 0.04mg to avoid acute reversal of analgesia

Monitor patient for possible return of respiratory depression.

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13
Q

Blocks/ Epidurals/ Pain Management

What are advantages of local anesthesia?

A

Postop analgesia on site
Safe for patients with systemic disease
Fewer side effects (PONV, sedation, respiratory depression)

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14
Q

Blocks/ Epidurals/ Pain Management

What is the MOA of local anesthesia?

A

Impairs conduction of nerve impulses
Alters cell permeability to Na2+
Attaches to site near Na2+ channel
Thus Na2+ channel is kept in closed position which slows depolarization and blocks conduction

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15
Q

Blocks/ Epidurals/ Pain Management

What are the disadvantages of local anesthesia?

A

Toxicity
Allergic reaction
IV injection
Inadvertent infiltration

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16
Q

Blocks/ Epidurals/ Pain Management

What are 2 different types of local anesthesia?

A

Esters and Amides

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17
Q

Blocks/ Epidurals/ Pain Management

What medications are classified as Esters - local anesthetics?

A

Esters (one “i”), ends with “caine”
1. Cocaine
2. Procaine
3. Chloroprocaine
4. Tetracaine

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18
Q

Blocks/ Epidurals/ Pain Management

What medications are classified as Amides - local anesthetics?

A

Amides (two “ii”), ends with “caine”
1. Prilocaine
2. Lidocaine
3. Mepivacaine
4. Bupivacaine
5. Etidocaine
6. Ropivacaine

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19
Q

Blocks/ Epidurals/ Pain Management

What to watch out for in administering Prilocaine (an Amide - local anesthetic)?

A

Can cause methemoglobinemia - abnormal amount of methemoglobin in the blood leading to hypoxia
d/t prilocaine toxic build up
s/s tachypnea, brown-grey cyanosis, metabolic acidosis, chocolate colored blood
Treat with methylene blue

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20
Q

Blocks/ Epidurals/ Pain Management

What to watch out for in administering Bupivacaine (an Amide - local anesthetic)?

A

Do not use for bier block
Can cause cardiac toxicity if excessive dose or accidental injection
Blocks sensory more than motor function

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21
Q

Blocks/ Epidurals/ Pain Management

What to watch out for in administering Mepivacaine (an Amide - local anesthetic)?

A

Do not use for spinal anesthesia
Great alternative to lidocaine with epinephrine without vasodilation effect

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22
Q

Blocks/ Epidurals/ Pain Management

How are local anesthetics metabolized?

A

Esters - hydrolyzed by plasma cholinesterase (aka acetylcholinesterase, produced by liver and ALSO BREAKS DOWN SUCCINYLCHOLINE)

Amides - metabolized by liver

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23
Q

Blocks/ Epidurals/ Pain Management

What are important properties of local anesthetics?

A
  1. Amides with more rapid onset
  2. Site infection and acidosis slows onset
  3. Increased risk of toxicity with hypoxia and acidosis
  4. Adding bicarbonate speed onset and decreases duration of effect
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24
Q

Blocks/ Epidurals/ Pain Management

What are important properties of local anesthetics?

A
  1. Adding vasoconstrictors (epinephrine) slows absorption of local anesthetics
  2. Adding vasoconstrictor decrease bleeding
  3. Absorption is dose related
  4. Highly vascular areas with faster systemic absorption
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25
# Blocks/ Epidurals/ Pain Management What is local anesthesia CNS toxicity?
Can occur d/t accidental injection into blood vessel or overdose
26
# Blocks/ Epidurals/ Pain Management What are the signs and symptoms of local anesthesia CNS toxicity ?
Lightheadedness Tinnitus ****Circumoral numbness**** Metallic taste in mouth Slurred speech Muscle twitching Can progress to grand mal seizures and coma** | Compare these symptoms vs. symptoms of MH
27
# Blocks/ Epidurals/ Pain Management What is the treatment for local anesthesia CNS toxicity ?
! Apply oxygen at first signs. May administer versed, valium, or thiopental for seizure activity | Why versed, valium or thopental?
28
# Blocks/ Epidurals/ Pain Management What are other treatments for local anesthesia CNS toxicity?
1. Early detection 2. Support circulation with fluids, vasopressors, antiarrhythmics 3. Oxygen, airway management 4. Control seizure activity
29
# Blocks/ Epidurals/ Pain Management What are other treatments for local anesthesia CNS toxicity?
CPR/ ACLS if necessary Lipid infusion * 20% lipid emulsion for reversal of toxicity * IV Push - 1.5mL/kg over 1 minute * Infusion - 0.25mL/kg/min * Max dose 12mL/kg | Note that lipid infusion is weight based
30
# Blocks/ Epidurals/ Pain Management How does 20% lipid emulsion reverse local anesthesia CNS toxicity?
Lipid emulsion binds to local anesthetic molecules which reduces the circulating amount of anesthetic that can bind to cardiovascular system. ## Footnote Odom-Forren J. Drain's Perianesthesia Nursing: A Critical Care Approach. 6th ed. St. Louis, MO: Saunders; 2013:321-322.
31
# Blocks/ Epidurals/ Pain Management What is local anesthesia cardiovascular toxicity?
**most common with Bupivacaine** d/t blocking of sodium channels in the heart s/s includes hypertension leading to hypotension, PVCs, prolonged PR interval, CV collapse
32
# Blocks/ Epidurals/ Pain Management What are the types of regional anesthesia?
Topical anesthesia Field block/ local infiltration IV injection Peripheral nerve block Sympathetic nerve blocks Neuraxial blocks (spinal, epidural)
33
# Blocks/ Epidurals/ Pain Management What are topical and local infiltration for regional anesthesia?
Topical - Applied directly to Skin, Mucus Membranes, Urethra, Nose, Pharynx Local Infiltration - ​ Direct tissue injection, Blocks transmission of sensory impulses, Epinephrine can be injected into confined spaces​
34
# Blocks/ Epidurals/ Pain Management What are standard tests for return of muscle function after neuromuscular blockade?
unaided **head lift** sustained while supine and strong **hand grips**, indicate approximately 50% of neuromuscular receptors returned to baseline ## Footnote Odom-Forren J. Drain's Perianesthesia Nursing: A Critical Care Approach. 6th ed. St. Louis, MO: Saunders; 2013:306.
35
# Blocks/ Epidurals/ Pain Management What is Bier Block (IV injection)?
Never use Bupivacaine for Bier Block ! d/t can cause cardiovascular collapse Tourniquet applied to occlude circulation of arm or leg Large doses of local anesthetic injected and stays in area d/t tourniquet Risk of toxicity when tourniquet released d/t anesthetic can travel to systemic circulation Common application: ganglion cyst removal, carpal tunnel release, tendon release
36
# Blocks/ Epidurals/ Pain Management Patient receives Bier block for surgical procedure. What are potential complications? a. cardiovascular depression b. permanent occlusion of artery c. pneumothorax d. Horner's syndrome
a. cardiovascular depression
37
# Blocks/ Epidurals/ Pain Management What is peripheral nerve block?
Anesthetic injected to specific site to block conduction of nerve impulses​​
38
# Blocks/ Epidurals/ Pain Management What are common types of peripheral nerve block?
1. Cervical plexus – common for carotid endarterectomy 2. Brachial plexus – 4 approaches​ Interscalene for shoulder surgery Supraclavicular ​ Axillary Infraclavicular​ 3. Intercoastal block
39
# Blocks/ Epidurals/ Pain Management What is cervical plexus block?
Used to block areas around neck Commonly used for **carotid endarterectomy**, superficial neck procedures
40
# Blocks/ Epidurals/ Pain Management What are complications of cervical plexus block?
Complications: Injury to vertebral artery Paralysis of diaphragm d/t phrenic nerve block Hoarseness for laryngeal nerve block Inadvertent subarachnoid or epidural block
41
# Blocks/ Epidurals/ Pain Management What is brachial plexus blocks: Interscalene/ supraclavicular?
Blocks arm from shoulder down (usually upper extremity surgery)
42
# Blocks/ Epidurals/ Pain Management What are the different approaches of brachial plexus block?
Interscalene Supraventricular Axillary Infraclavicular
43
# Blocks/ Epidurals/ Pain Management What are the complications of Interscalene/ supraclavicular block?
**Horner syndrome** (hoarseness of voice, ptosis, miosis-constriction of pupil, decreased sweating, nasal congestion on the affected side) d/t blockade of stellage ganglion Unilateral phrenic + laryngeal nerve block Vertebral artery injection Possible high spinal or epidural Pneumothorax (check breath sounds)
44
# Blocks/ Epidurals/ Pain Management What is the nursing intervention in case of Horner syndrome?
Reassure the patient that the experience is self limiting. The complication will resove as soon as the local anesthetic wears off.
45
# Blocks/ Epidurals/ Pain Management What is high spinal block?
Excessive spread of local anesthetic during spinal or epidural anesthesia. s/s include high sensory block resulting in **upper extremity sensory and motor changes**, nausea and vomiting, loss of consciousness, anxiety, hypotension, bradycardia or asystole, respiratory distress, or apnea. ## Footnote Odom-Forren J. Drain's Perianesthesia Nursing: A Critical Care Approach. 6th ed. St. Louis, MO: Saunders; 2013:267.
46
# Blocks/ Epidurals/ Pain Management What is axillary block?
Most popular, easy and safe Commonly used for forearm, wrist and hand procedures
47
# Blocks/ Epidurals/ Pain Management What are complications of axillary block?
IV injection Hematoma if axillary artery is punctured Contraindicated if patient with infected glands or the arm can not be abducted to 90 degrees at the shoulder
48
# Blocks/ Epidurals/ Pain Management What is intercoastal block?
Useful for post op pain s/p thoracic or abdominal surgery, chest tube insertion Also for rib fractures and neurolytic block for cancer
49
# Blocks/ Epidurals/ Pain Management What are complications of intercoastal block?
Pneumothorax IV injection !Toxicity d/t rapid uptake by intercoastal
50
# Blocks/ Epidurals/ Pain Management What is transverse abdominal plane block?
Local anesthetic injected to plane between internal oblique and transversus abdominis muscles Interrupts innervation to abdominal skin, muscles, parietal peritoneum
51
# Blocks/ Epidurals/ Pain Management What are common use for abdominal plane block?
bowel resections, ventral hernia repair, cholecystectomy, kidney transplant, total abdominal hysterectomy, C-sections
52
# Blocks/ Epidurals/ Pain Management What is lower extremity block?
Indicated for procedures at or below knee Lumbar plexus (psoas compartment block) Femoral nerve block Popliteal sciatic nerve block Saphenous nerve block Ankle block
53
# Blocks/ Epidurals/ Pain Management What are complications of lower extremity blocks?
IV injection Inadvertent arterial puncture Neural trauma
54
# Blocks/ Epidurals/ Pain Management What are the types of neuraxial blocks?
Spinal anesthesia Epidural anesthesia
55
# Blocks/ Epidurals/ Pain Management What are other miscellaneous blocks?
Paravertebral block (mastectomy) Retrobulbar/ Peribulbar block (intraocular lens implant, posterior chamber/ retinal surgery, corneal implant, cataract surgery) Airway block (difficult intubation, upper airway trauma, cervical spine fracture or radiculopathy, airway malignancy or abscess)
56
# Blocks/ Epidurals/ Pain Management What is spinal anesthesia (intrathecal or subarachnoid block)?
Anesthesia on subarachnoid space Anesthetize nerve root + part of spinal cord Spinal - blocks nerve conduction in the region of body Toxicity is rare d/t small doses given !Baracity (heaviness of solution) 5-10% glucose added to anesthetic solution makes medication heavier than CSF Helps sink solution in CSF, thus affected by gravity + patient's position
57
# Blocks/ Epidurals/ Pain Management What is subarachnoid space?
Web like Contains CSF, arteries, veins
58
# Blocks/ Epidurals/ Pain Management What is epidural anesthesia?
Injected into epidural space Can be single, bolus, or continuous infusion (PCEA) Higher chance of systemic toxicity d/t large dose req More absorption to systemic circulation Higher incidence of post Dural puncture headache
59
# Blocks/ Epidurals/ Pain Management What is epidural space?
Potential space only Must be created when accessed for injection of anesthetic
60
# Blocks/ Epidurals/ Pain Management What is site or mechanism of action for spinal vs. epidural?
!Spinal - Nerve roots blocked as they pass through CSF !Epidural - Nerve roots blocked outside CSF
61
# Blocks/ Epidurals/ Pain Management What is the administration site for spinal vs. epidural?
!Spinal - Lower lumbar below termination of spinal !Epidural - Lumbar or thoracic region
62
# Blocks/ Epidurals/ Pain Management What is the dose of anesthetic for spinal vs. epidural?
!Spinal - small !Epidural - large
63
# Blocks/ Epidurals/ Pain Management What is the instrument for administration for spinal vs. epidural?
!Spinal - needle !Epidural - needle or catheter
64
# Blocks/ Epidurals/ Pain Management What is the ability to repeat for spinal vs. epidural?
!Spinal - no !Epidural - yes
65
# Blocks/ Epidurals/ Pain Management What is the onset of action for spinal vs. epidural?
!Spinal - rapid, intense blockade, may lead to hypotension !Epidural - gradual, may have less intense blockade, BP decline is usually slower
66
# Blocks/ Epidurals/ Pain Management Patient develops N/V s/p spinal anesthesia. Perianesthesia knows most concerning symptom requiring intervention: hypothermia spinal headache hypotension bladder distension
hypotension
67
# Blocks/ Epidurals/ Pain Management What are significant considerations for neuraxial anesthesia (spinal/ epidural)?
Assess dermatomes to evaluate evolution, extent of anesthesia Progress of block affected by many factors like Dose + volume administered Patient's position s/p administration Obesity, hormonal influence, pregnancy
68
# Blocks/ Epidurals/ Pain Management What to watch out for in neuraxial anesthesia (spinal/ epidural)?
!Loss of temperature sensation first sign of sensory block Feet affected first, then moves upward body
69
# Blocks/ Epidurals/ Pain Management What are the indications for epidural anesthesia?
Surgical procedure involving lower extremity, perineum, abdomen Treatment of acute and chronic pain Obstetric procedure and labor analgesia
70
# Blocks/ Epidurals/ Pain Management What are relative contraindications to epidural anesthesia?
Preexisting neural disease Musculoskeletal abnormalities History of back surgery Untreated hypertension
71
# Blocks/ Epidurals/ Pain Management What are absolute contraindications of epidural anesthesia?
Patient refusal CVD - severe AS, mitral stenosis, asymmetrical septal hypertrophy Severe uncorrected hypovolemia Allergy to anesthetic agent Increased ICP Infection at injection site Sepsis or bacteremia Coagulopathy
72
# Blocks/ Epidurals/ Pain Management What are precautions for epidural anesthesia?
Patients on anticoagulant can experience catastrophic complications
73
# Blocks/ Epidurals/ Pain Management What are the dermatomes?
Each dermatome correspond to specific nerve root Neck - C3 Clavicles - C5 Nipples - T4 - Cesarean section, upper abdomen, uterine Xiphoid - T6/T7 - Lower abdomen Navel - T10 - Hip and **genitourinary** Groin - L1 to L3 - Lower extremities Knee - L4 Dorsum of foot - L5 Lateral ankles - S1
74
# Blocks/ Epidurals/ Pain Management What is the order for Loss/ Return of function during neuraxial anesthesia (spinal/ epidural)?
Autonomic + Sympathetic Function > sense of temperature > pain > touch > movement > proprioception (sense that lets us perceive the location and movements of our body parts - https://www.sciencedirect.com/topics/neuroscience/proprioception) !Return of function is in the order of reversal of loss
75
Which of the following describes the recovery sequence from spinal anesthesia as indicated by dematome level? Lower extremities, abdomen, chest, perineum Chest, abdomen, perineum, lower extremities Chest, abdomen, lower extremities, perineum Lower extremities, perineum, abdomen, chest
Chest, abdomen, lower extremities, perineum
76
# Blocks/ Epidurals/ Pain Management When is safe to discharge patient after neuraxial anesthesia (spinal/ epidural)?
!Inpatient - T10 level (navel) indicates that the spinal/ epidural is resolving !Outpatient - S3 level ( ) indicates fully resolved per facility policy consider ability to void
77
# Blocks/ Epidurals/ Pain Management What to watch out for in neuraxial anesthesia (spinal/ epidural)?
!Blocks higher than T6 but less than T3 HYPOTENSION more likely Sympathetic output from the spinal cord is blocked HR may increase in response
78
# Blocks/ Epidurals/ Pain Management What to watch out for in neuraxial anesthesia (spinal/ epidural)?
!Blocks higher than T3 BRADYCARDIA more likely Function of SA node can be affected (vagus nerve is unrestrained)
79
# Blocks/ Epidurals/ Pain Management What to watch out for in neuraxial anesthesia (spinal/ epidural)?
!Blocks higher than T1 Cardiopulmonary collapse
80
# Blocks/ Epidurals/ Pain Management Patient received spinal anesthesia. BP=70/40, HR=38, RR=14, SPO2=96%. No sensation below T3 dermatome level. RN needs to anticipate which priority intervention? immediate reintubation atropine administration monitoring cardiopulmonary arrest starting dopamine infusion
starting dopamine infusion
81
# Blocks/ Epidurals/ Pain Management What is the treatment for hypotension d/t neuraxial anesthesia (spinal/ epidural)?
Elevate patient's legs (but can worsen block). AVOID elevating head/ HOB. AVOID trendelenburg d/t increased risk of respiratory compromise, upward spread of anesthesia. IV fluid bolus Vasopressors for BP support (i.e. phenylephrine) IV atropine if pronounced bradycardia !High sensory block can lead to neurogenic shock
82
# Blocks/ Epidurals/ Pain Management What are potential complications of neuraxial anesthesia (spinal/ epidural)?
Postdural puncture headache d/t CSF leak in dura mater: More common in spinal anesthesia More likely if large needle/ hole used More likely occurs in younger people More likely if sharp needles than blunt needles
83
# Blocks/ Epidurals/ Pain Management What are the signs/ symptoms of postdural puncture headache?
Symptoms appear 24-48 hours after dura puncture: HA worsened by sitting/ standing Nuchal rigidity Neck ache Nausea Visual and auditory disturbances
84
# Blocks/ Epidurals/ Pain Management What are the treatments for postdural puncture headache?
Hydration Caffeine Blood patch
85
# Blocks/ Epidurals/ Pain Management What are potential complications of neuraxial anesthesia (spinal/ epidural)?
Adhesive arachnoiditis: chronic inflammation of arachnoid progressive weakness/ sensory loss on lower limbs leads to paraplegia
86
# Blocks/ Epidurals/ Pain Management What are potential complications of neuraxial anesthesia (spinal/ epidural)?
Cauda equine syndrome: leg numbness, bowel/ bladder dysfunction usually permanent effects
87
# Blocks/ Epidurals/ Pain Management What are potential complications of neuraxial anesthesia (spinal/ epidural)?
Septic meningitis (symptoms appear within 24 hours of injection): fever, ha, neck rigidity, + Kernig's sign (chin can't touch chest) good outcome with early antibiotic treatment
88
# Blocks/ Epidurals/ Pain Management What are potential complications of neuraxial anesthesia (spinal/ epidural)?
Complete loss of chest wall sensation and c/o increasing difficulty breathing (suspect phrenic nerve paralysis - needs emergent intubation)
89
# Blocks/ Epidurals/ Pain Management What are potential complications of neuraxial anesthesia (spinal/ epidural)?
Epidural hematoma - for patients with coagulopathies S/S include sudden lower back pain, motor and sensory changes, bowel and bladder deficits Treatment - emergent MRI/ CT/ spinal decompression
90
# Blocks/ Epidurals/ Pain Management What are potential complications of neuraxial anesthesia (spinal/ epidural)?
Nausea and vomiting caused by hypotension
91
# Blocks/ Epidurals/ Pain Management What are contraindications to neuraxial anesthesia (spinal/ epidural)?
Patient refusal Coagulation deficiency Infection at block site