Miscellaneous CPAN Topics Flashcards
Miscellanous CPAN Topics
What are the screening tools for OSA?
Berlin Questionnaire (limited application in preop)
STOP - BANG (excellent predictor of severe OSA but average predictor for diagnosis of OSA)
ASA OSA Checklist
Miscellanous CPAN Topics
How to score OSA using
STOP-Bang?
Miscellanous CPAN Topics
What is the STOP Bang scoring criteria for OSA?
0-2 Low risk OSA
3-4 Intermediate risk
5-8 High risk (includes male/BMI >35/ + neck circ)
Miscellanous CPAN Topics
What is the most advantageous position for a patient with OSA postoperatively?
Lateral recumbent
Avoid supine unless clinically indicated
Miscellanous CPAN Topics
When can diagnosed or suspected OSA patient can be safely discharged in Phase II?
No evidence of hypoxia or obstruction when patient is left undisturbed for 30 minutes
Miscellanous CPAN Topics
How many days before surgery should patient stop taking St. John’s Wort?
7 days
Herb same MOA as MAOIs/SSRIs/ antidepressant
Potentiates anesthetic effects
May affect BP
Miscellanous CPAN Topics
How many days before surgery should patient stop taking saw palmetto?
2 weeks
Increases urine flow, decrease urine frequency
May increase INR with warfarin
Miscellanous CPAN Topics
How many days before surgery should patient stop taking black cohosh?
2 weeks
Herb w/ estrogen, anti inflammatory effect
May cause hypotension, bradycardia
Miscellanous CPAN Topics
How many days before surgery should patient stop taking Gingko biloba?
2 weeks
Herb inhibits platelets and it is antioxidant
May potentiate anticoagulant effects
In general garlic, ginger, ginko increase risk of bleeding.
Miscellanous CPAN Topics
How many days before surgery should patient stop taking kava-kava?
24 hours
Herb a sedative hypnotic
Avoid use with benzo, etoh, barbiturates
DO NOT use with Parkinson’s medications
Miscellanous CPAN Topics
What is ephedra?
ephedra (from Chinese herb ma huang) contains ephedrine, an amphetamine-like compound closely related to adrenaline
It can cause tacyhcardia and elevated blood pressure, nausea and vomitting.
Reactions include heart attacks, strokes, seizures, and sudden deaths
The dangers of the herb ephedra. January 20, 2017
https://www.health.harvard.edu/staying-healthy/the-dangers-of-the-herb-ephedra
Miscellanous CPAN Topics
How much change in HGB/ HCT per 1 unit of PRBC (250cc, w/ RBCs + platelets)?
Hgb increase by 1 g/dL
Hct increase by 3%
Miscellanous CPAN Topics
How much change in platelet if given 1 pack = 50-300ml?
1 unit of platelets increases platelet concentration in the adult by 5000/mm(3) to 10,000/mm(3).
Platelet concentrate is usually suspended in 50ml plasma.
Miscellanous CPAN Topics
Patient is s/p wound debridement, febrile, with gross hemoglobinuria and flushed skin. Patient having which type of blood transfusion reaction:
anaphylactic
allergic
hemolytic
citrate intoxication
hemolytic
ABO-incompatibility precipitates hemolytic reaction thru aglutination of RBCs, which blocks patient’s capillaries and obstructs O2/blood flow to vital organs. Hemolysis of RBCs release hemoglobin into the plasma w/c plugs renal tubules.
Bleeding suggests patient received incompatible blood.
Miscellanous CPAN Topics
What is febrile non-hemolytic blood transfusion reaction?
Febrile reactions caused by sensitivity to leukocytes and plateles.
Symptoms does not occur as rapidly in hemolytic reactions
headache
chills
fever
backache
nausea
vomitting
Miscellanous CPAN Topics
What is anaphylactic blood transfusion reaction?
Anaphylactic reactions frequently seen in platelet transfusion. Patients with history of mod-severe allergic reaction benefits from pre-medication with histamine. Symptoms include
rash
pruritus
localized angioedema
urticaria (minor allergic reaction)
wheezing (more severe allergic reaction)
laryngeal edema (more severe allergic reaction)
hypotension (more severe allergic reactions)
Miscellanous CPAN Topics
What is lung injury blood transfusion reaction?
Patients who receive plasma-containing products, at risk for Transfusion-Related Acute Lung Injury. Symptoms include
noncardiogenic pulmonary edema
dyspnea
hypoxemia
fever
hypotension
Miscellanous CPAN Topics
What is citrate intoxication during blood transfusion?
Citrate intoxication d/t large amounts transfusion when blood is infused raplidly. Liver unable to metabolize citrate ions, that combine with calcium and cause calcium deficit symptoms such as tingling of the fingers, muscular cramps, and nervousness. If not corrected, cardiac dysrhythmias including ventricular fibrillation can occur. Treatment consists of slow IV administration of calcium gluconate, 1 g for every 1000 mL of blood the patient received. If calcium gluconate is unavailable, calcium chloride can be used, but this is more irritating to the veins.
Name cranial nerves I-VI
I – Olfactory: Sense of smell
II – Optic: Sight
III – Oculomotor: Pupil, upper eyelid, eye movements
IV – Trochlear: Downward/inward eye movement
V – Trigeminal: Sensation of cornea, cheek/lips, chin; control of biting and chewing muscles
VI – Abducens: Lateral eye movements
Name Cranial Nerves VII-XII
VII – Facial: Movement of facial muscles; taste
VIII – Acoustic: Equilibrium; hearing
IX – Glossopharyngeal: Swallowing muscles; taste
X – Vagus: Pharynx/larynx sensation; movement of soft palate
XI – Spinal accessory: Sternocleidomastoid, trapezius muscles
XII – Hypoglossal: Movement of tongue
Miscellanous CPAN Topics
Which cranial nerves are assessed after carotid endarterectomy?
Facial (VII)
Glossopharyngeal (IX)
Vagus (X)
Spinal accessory (XI)
Hypoglossal (XII)
What is Cerebral Perfusion Pressure?
Brain perfusion calculated as
CPP=MAP - ICP
Normal range 70-100mmHg
Minimal adequate value @ 60mmHg
What is normal ICP?
Normal ICP 0 - 15 mmHg
Goal of care is to maintain ICP < 20 mmHg
Treatment starts when ICP > 20 mmHg
What are common signs and symptoms of ICP increase complication?
Hypertension
Bradycardia
Respiratory disturbances