blood and blood vessels Flashcards

1
Q

what separates blood

A

being spun in a centrifuge

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2
Q

components of blood =

A

erythrocytes ~45%
buffy coat (leukocytes and platelets) <1%,
plasma ~55%

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3
Q

what does plasma have

A

clotting factors

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4
Q

what removes clotting factors

A

serum

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5
Q

explain Erythrocytes (RBCs)

A
  • Biconcave discs around 7µm in diameter
  • No nucleus or organelles (when mature)
  • Network of flexible cytoskeletal elements
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6
Q

explain Neutrophils

A
  • 40-75% of WBCs
  • Phagocytes (when activated)
  • Single, multi-lobed nucleus
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7
Q

explain Eosinophils

A
  • 5% of WBCs
  • Acidic granules that stain red, and a bi-lobed nucleus
  • Granules contain hydrolytic enzymes - inflammation
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8
Q

explain Basophils

A
  • 5% of WBCs
  • Basic granules that stain purple/blue, and a bi-lobed nucleus
  • Effector cells in allergic reactions
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9
Q

explain Monocytes

A
  • 1-5% of WBCs
  • Precursors of tissue macrophages (phagocytes)
  • Large, kidney bean-shaped nucleus
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10
Q

explain lymphocytes

A
  • 0-50% of WBCs
  • Small spherical nucleus and basophilic (blue) cytoplasm
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11
Q

B cells:

A

give rise to antibody secreting plasma cells

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12
Q

T cells:

A

differentiate in thymus, many defensive functions

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13
Q

what are platelets

A

Cell fragments that have a key role in haemostasis

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14
Q

Tunica intima: (structure of arteries)

A

single layer of squamous epithelial cells (endothelium) supported by a basal lamina and a thin layer of connective tissue

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15
Q

Tunica media: (structure of arteries)

A

predominantly made up of smooth muscle

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16
Q

Tunica adventitia: (structure of arteries)

A

made up of supporting connective tissue

16
Q

arteriole

A

1 or 2 layers of smooth muscle in tunica media, almost no adventitia

17
Q

Capillaries

A

Endothelial cells and a basal lamina

18
Q

what are the 3 types of capillaries

A
  • Continuous: no pores
  • Fenestrated: small pores
  • Discontinuous: large gaps
19
Q

Postcapillary venules:

A

endothelium and thin layer of connective tissue

20
Q

venules:

A

intermittent smooth muscle in tunica media

21
Q

veins

A

Tunica intima, a thin, continuous tunica media and a tunica adventitia