Blood Aq Barrier And Formation Of Vitreous

Question 1

Are tight junctions present in NPCE or PCE

Answer 1

NPCE

Question 2

Barrier to the movement of intermediate and high molecular weight substances such as protein

Answer 2

Blood aqueous barrier

Question 3

Barrier protecting the eye from entry of toxic substances nad maintained the homeostatic control that underpins the ocular physiology

Answer 3

BAB

Question 4

Explains why drugs administered ortally or IV can hardly reach therapeutic levels in intraocular tiussue

Answer 4

BAB

Question 5

What constitutes an effective barrier to intermediate and high molecular weight substances such as proteins

Answer 5

Tight junctions between NPCE cells

Question 6

Cells and flares in the anterior chamber

Answer 6

Uveitis

• inflammatory cells
• causes barrier breakdown and causes proteins to come in (flares)

Question 7

Trauma and BAB

Answer 7

Hyphema

Breakdown of the barrier, so blood comes into anterior segment

Question 8

Causes of BAB breakdown

Answer 8

Ocular injuries 
Ocular hypotony (low pressure)

Question 9

Ocular injuries mechanisms of BAB breakdown

Answer 9

Inflammation

Question 10

Ocular hypotony mechanism of BAB breakdown

Answer 10

Opening of the non-penetrated endothelial layer of the iris caps; and the tight junctions of the ciliary epithelium; increases epi scleral venous pressure

Question 11

Clear gel which occupies the posterior compartment of the eye

Answer 11

Vitreous

Question 12

Primary vitreous

Answer 12

3-4 gestational stage

• optic cup filled by system of fibrillation material
• VEGF causes hylaoid artery penetration

Question 13

Secondary vitreous

Answer 13

6th week gestational weeks

• increasing of size
• antiVEGF causes hyoid to disappear
• cloquets canal formed

Question 14

Tertiary vitreous

Answer 14

Controversial

-Secreted by NPCE of pars plans and persists in the adult as the suspensory ligament of the lens

Question 15

Arises from the center of the optic disc, consitis of a small tuft of fibrous tissue and represents a remnant of the fetal hylaoid artyer

Answer 15

Bergmeister’s Papillae

Question 16

Small, circular opacity on the posterior lens capsule, classically nasal in location, which represents the anterior attachment of the hyaloid artery

Answer 16

Mittendorfs dot

Question 17

Tubular structure containing remnants of the primary vitreous, located between the posterior aspect of the lens and the retina in the vicinity of the optic disc

Answer 17

Cloquet’s Cana l

Question 18

Vitreous cortex, also called hyaloid surface

Answer 18

Outmost zone

Question 19

Cloquets canal

Answer 19

Center zone

Question 20

Inner to the cortex and surrounds the center canal

Answer 20

Intermediate zone

Question 21

Which one is the major part of the BAB

Answer 21

Tight junction between NPCE

Question 22

Which one is allow to pass the posterior chamber

Answer 22

Ions and water

Question 23

Which one can cause BAB breakdown

Answer 23

Uveitis

Question 24

Which one is primary vitreous

Answer 24

Hyaloid

Question 25

Which one is not rememnat of Hoyaloid artery

Answer 25

Zonular fibers

Question 26

Which one is the poutmost zone of vitreous

Answer 26

Vitreous cortex