Formation And Function Of Aqueous Humor Flashcards
Clear colorless fluid that fills the anterior and posterior chamber of the eye
Aqueous humor (AH)
Functions of aqueous humor
- nutrients and O2 to remove metabolic wastes from the anterior intraocular tissues
- inflates the eye globe and creates IOP for normal and optical functioning of the eye
- transports asocrbic acid into anterior where is serves as an antioxidant agent
- facilitates the local immune responses during inflammation and infection
Primary site of AH formation
Par plicata
What layer of epithelium forms AH
NPCE
Average rate of formation of aqueous humor
2.75ul/min (daytime) and 1.08ul/min (night)
When is aqueous production increased
Daytime
What makes you 99% of AH
Water
Where is ascorbic acid higher, blood or AH
AH
Where is protein higher, blood or AH
Blood
Purpose of ascorbic acid in AH
Against photo-oxidative damage
Purpose of low protein in AH
Free of protein to maintain optical transparency
Where do all the proteins in the AH come from
Blood plasma, not synthesized
How does blood synthesize Ah
- Blood flow to ciliary stroma
- Loading solutes from blood plasma to pigmented epithelium
- Solutes translocates to NPCE through gap junctions
- Solutes excluded from NPCE into posterior chamber
- Osmotic gradient create, causing passive water flow to posterior chamber
Mechanisms of solutes across the CE
- Diffusion
- Ultrafiltration
- Active transport
What is the major player in moveing solutes across the CE
Active transport
