BLOOD* CH 18 Flashcards

(43 cards)

1
Q

Identify and describe 2 (/3) main functions of the circulatory system

A

Transport - Oxygen, nutrients, waste etc
Protection - Of our bodies from infection, disease, and disorders
Regulation - Of fluid balance, pH, and temperature

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2
Q

What are the formed elements of blood?

A

Erythrocytes
Leukocytes
Thrombocytes

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3
Q

What is plasma mostly composed of?

A

Water

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4
Q

Define Hematocrit. How can it be affected (identify three)?

A

The total volume of whole blood that is red blood cells

Hydration
Blood Loss
Production Issues
Gender Differences (lower values in women)

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5
Q

What stem cell gives rise to all formed elements?

A

Hemocytoblasts

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6
Q

Do RBCs have mitochondria? Why?

A

No. They do not use oxygen, they deliver it

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7
Q

What molecule in hemoglobin binds to oxygen? How many oxygen molecules can one hemoglobin molecule carry?

A

Iron
4

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8
Q

What is the term for erythrocyte production? What hormone controls this?

Spell them correctly*

A

Erythropoiesis
Erythropoietin

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9
Q

What is Hypoxemia? What are some causes?

A

Oxygen deficiency in blood

Not enough RBCs (to carry oxygen) or Oxygen
- High Altitude
- Increased exercise

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10
Q

What is Polycythemia? What are some causes?

A

Excess amount of RBCs that increase blood viscosity making it thicker and sticky

Bone Marrow Cancer
When minimal oxygen is available (high altitudes)
Erythropoietin production increase

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11
Q

Identify and describe the types of anemia that result from insufficient erythrocytes

A

Hemorrhagic Anemia - Bleeding
Hemolytic Anemia - RBC destruction
Aplastic Anemia - Inability to form RBC

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12
Q

Identify and describe the types of anemia that result from low hemoglobin content

A

Iron-deficiency Anemia - Iron deficient
Pernicious Anemia - Deficiency of vitamin B12

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13
Q

What is Thalassemias?

A

Delicate RBCs cannot carry adeqaute oxyegn

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14
Q

What are three potential consequences of anemia?

A

Hypoxia - SOB, Lethargic
Tissue Swelling
Low Blood Viscosity - Too thin, Heart racing

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15
Q

Hypoxemia vs Hypoxia

A

Hypoxemia - Low Oxygen in Blood
Hypoxia - Low Oxygen going to Tissues

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16
Q

Describe Sickle Cell Disease

A

Hereditary disorder that codes for abnormal hemoglobin and is mishapen

This causes a low amount of oxygen to flow through body

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17
Q

What antigens are on the surface of RBCs for each blood type?

A

A - Antigen A
B - Antigen B
AB - Antigens A AND B
O - NONE

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18
Q

What are the antibodies within the plasma for each blood type?

A

A - Antibody B
B - Antibody A
AB - NONE
O - Antibody A AND B

19
Q

What is the universal donor blood type?

20
Q

What is the universal recepient blood type?

21
Q

What does the Rh antigen determine in terms of blood type?

A

Positive or Negative Blood Types

22
Q

What is HDN? How can it be prevented?

A

When a woman has a baby with mismatched blood type (a negative and positive difference)

RhoGAM

23
Q

Identify the granulocytes and agranulocytes

A

Granulocytes: BEN (-phils)
Basophils
Eosinophils
Neutrophils

Agranulocytes: LM (-cytes)
Lymphocytes
Monocytes

24
Q

List the five leokocytes from most numerous to least numerous in the blood

A

Never Let Monkeys Eat Bananas

Neutrophils
Lymphocytes
Monocytes
Eosinophils
Basophils

25
What pathogens do each of the five leukocytes respond to?
Neutrophils - Bacteria Lymphocytes - Viruses Monocytes - Bacteria Eosinophils - Parasitic Worms Basophils - Allergies BVBPA
26
Lymphoid vs Myeloid Stem Cells
Lymphoid - Forms ONLY Lymphocytes Myeloid - FORMS ALL OTHER WBCs
27
Leukopenia
Low WBC count: causes elevated risk of infection
28
Leukocytosis
High WBC count: present in those fighting off a disease, infection, or virus
29
Leukemia Acute vs Chronic
Acute - Develops quickly, causes death within months Chronic - Develops slowly and goes undetected for months, survival time of 3 years
30
What is leukemia?
Cancer causing too many WBCs
31
What cells are platelets fragements of?
Megakaryocytes
32
What is thrombocytopenia?
Deficiency of thrombocytes (platelets)
33
Identify and briefly describe the three steps of hemostasis
Vascular Spasm - Constiction of Blood Vessels Platelet Plug Formation - Coagulation (Blood Clotting) - Reinforcing the plug
34
What type of feedback cycle is platelet plug formation?
Positive Feedback
35
What chemical keeps platelets from plugging uninjured tissues?
Prostacyclin
36
Identify and describe the phases of blood clotting
Factor X forms Prothrombin Activator Prothrombin Activator forms Thrombin Thrombin causes fibrinogen to form a fibrin mesh
37
What is the role of PDGF?
Recreate cells in the area of injury
38
What is the the role of fibrinolysis?
Break down blood clot
39
What enzyme breaks down a clot?
Plasmin
40
What are anticoagulants?
Deactivates thrombin so as to prevent blood clotting
41
What is hemophilia?
A family of hereditary diseases where the patient cannot form blood clots
42
Thrombosis vs Embolus
Thrombosis - Abnormal formation of a clot in an uninjured blood vessel Embolus - When a thrombus breaks loose and travels
43
RBCs and WBCs. Which have a nucleus?
WBCs only