BLOOD COMPONENTS AND DERIVATIVES Flashcards

(42 cards)

1
Q

Massive transfusion where both red cell mass and plasma volume are required

A

Whole blood

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2
Q

Replacement of the O2 carrying capacity and maintenance of the intravascular volume

A

Whole blood

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3
Q

Used in active brisk bleeding

A

Whole blood

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4
Q

A product in w/c all of the red cells & most of the plasma from the original unit remain

A

Whole blood

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5
Q

ml of whole blood

A

540 ml

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6
Q

Shelf life of whole blood

A

CPD – 21 days;
CPDA1 – 35 days at 1-6°C

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7
Q

Packed RBC with reduced plasma (avoid circulatory overload) volume

A

Red blood cells

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8
Q

Red blood cells may be prepared from whole blood by overnight

A

Sedimentation or by centrifugation using heavy spin

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9
Q

To increase O2 carrying capacity of blood in patients with acute/ chronic anemia

A

Red blood cells

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10
Q

ml of red blood cells

A

260 ml

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11
Q

Shelf life of red blood cells

A

CPD – 21 days;
CPDA1 – 35 days at 1-6°C

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12
Q

RBCs with reduced plasma volume and an additional of 100 mL additive solution

A

RED BLOOD CELLS IN ADDITIVE SOLUTION (ADENINE-SALINE)

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13
Q

mL of RED BLOOD CELLS IN ADDITIVE SOLUTION (ADENINE-SALINE)

A

340 ml

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14
Q

Shelf life of RED BLOOD CELLS IN ADDITIVE SOLUTION (ADENINE-SALINE)

A

42 days at 1-6°C

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15
Q

Prevention of recurrent or severe allergic reactions

A

WASHED RBCS ( NO PLASMA )

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16
Q

WASHED RBCS ( NO PLASMA ) is used for what transfusion

A

Neonatal intrauterine transfusion

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17
Q

Prevention of anaphylactic reactions in IgA-deficient patients

A

WASHED RBCS ( NO PLASMA )

18
Q

Shelf life of WASHED RBCS ( NO PLASMA )

A

24 hours at 1-6°C

19
Q

Removes >90% of WBC
No plasma

A

FROZEN DEGLYCEROLIZED RBCS

20
Q

Long-term preservation of RBC units with rare phenotype or autologous RBC units

A

FROZEN DEGLYCEROLIZED RBCS

21
Q

Alternative to CMV-seronegative units in
emergencies

A

FROZEN DEGLYCEROLIZED RBCS

22
Q

Decreases febrile transfusion reactions

A

FROZEN DEGLYCEROLIZED RBCS

23
Q

mL of FROZEN DEGLYCEROLIZED RBCS

24
Q

Shelf life of FROZEN DEGLYCEROLIZED RBCS

A

10 years at -65°C to -200°C
24 hours at 1-6°C after washing (AG:40% glycerol)

25
Decreases risk of alloimmunization to HLA antigens on leukocytes
LEUKOCYTE-REDUCED RBCS
26
Decrease febrile non-hemolytic transfusion reactions
LEUKOCYTE-REDUCED RBCS
27
Reduce the risk of CMV infection
LEUKOCYTE-REDUCED RBCS
28
Decrease immunomodulation, and may decrease the risk of prion transmission in B lymphocytes
LEUKOCYTE-REDUCED RBCS
29
3 log filtration
LEUKOCYTE-REDUCED RBCS
30
Two RBC is divided into two separate RBC units of equal volume
TWO-UNIT RBCS, APHERESIS
31
Similar to pRBC (increase oxygen carrying capacity)
TWO-UNIT RBCS, APHERESIS
32
Volume of TWO-UNIT RBCS, APHERESIS
320 ml
33
Shelf life of TWO-UNIT RBCS, APHERESIS
1 year at 1-6 °C
34
Bleeding due to quantitative and qualitative platelet disorders
RANDOM DONOR PLATELET CONCENTRATE
35
Prophylaxis in severely thrombocytopenic patients (5,000 – 10,000/uL)
RANDOM DONOR PLATELET CONCENTRATE
36
Volume of RANDOM DONOR PLATELET CONCENTRATE
50 - 70 mL
37
Shelf life of RANDOM DONOR PLATELET CONCENTRATE
5 days at 20-24 °C with constant gentle agitation & 4 hours after pooling
38
Platelets in approx. 250ml of plasma to maintain pH above 6.2 ▪ Indications, similar to random donor platelets
PLATELETS, PHERESIS (SINGLE DONOR PLATELETS)
39
Volume of PLATELETS, PHERESIS (SINGLE DONOR PLATELETS)
200 - 400 ml
40
Shelf life of PLATELETS, PHERESIS (SINGLE DONOR PLATELETS)
5 days at 20-24°C with constant gentle agitation
41
3rd gen filter
LEUKOCYTE REDUCED PLATELETS
42
Bedside filtration is done immediately before transfusion (3log filters)
LEUKOCYTE REDUCED PLATELETS