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ISBB!!!! > BLOOD COMPONENTS AND DERIVATIVES > Flashcards

BLOOD COMPONENTS AND DERIVATIVES Flashcards

1
Q

Massive transfusion where both red cell mass and plasma volume are required

A

Whole blood

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2
Q

Replacement of the O2 carrying capacity and maintenance of the intravascular volume

A

Whole blood

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3
Q

Used in active brisk bleeding

A

Whole blood

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4
Q

A product in w/c all of the red cells & most of the plasma from the original unit remain

A

Whole blood

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5
Q

ml of whole blood

A

540 ml

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6
Q

Shelf life of whole blood

A

CPD – 21 days;
CPDA1 – 35 days at 1-6°C

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7
Q

Packed RBC with reduced plasma (avoid circulatory overload) volume

A

Red blood cells

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8
Q

Red blood cells may be prepared from whole blood by overnight

A

Sedimentation or by centrifugation using heavy spin

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9
Q

To increase O2 carrying capacity of blood in patients with acute/ chronic anemia

A

Red blood cells

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10
Q

ml of red blood cells

A

260 ml

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11
Q

Shelf life of red blood cells

A

CPD – 21 days;
CPDA1 – 35 days at 1-6°C

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12
Q

RBCs with reduced plasma volume and an additional of 100 mL additive solution

A

RED BLOOD CELLS IN ADDITIVE SOLUTION (ADENINE-SALINE)

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13
Q

mL of RED BLOOD CELLS IN ADDITIVE SOLUTION (ADENINE-SALINE)

A

340 ml

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14
Q

Shelf life of RED BLOOD CELLS IN ADDITIVE SOLUTION (ADENINE-SALINE)

A

42 days at 1-6°C

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15
Q

Prevention of recurrent or severe allergic reactions

A

WASHED RBCS ( NO PLASMA )

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16
Q

WASHED RBCS ( NO PLASMA ) is used for what transfusion

A

Neonatal intrauterine transfusion

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17
Q

Prevention of anaphylactic reactions in IgA-deficient patients

A

WASHED RBCS ( NO PLASMA )

18
Q

Shelf life of WASHED RBCS ( NO PLASMA )

A

24 hours at 1-6°C

19
Q

Removes >90% of WBC
No plasma

A

FROZEN DEGLYCEROLIZED RBCS

20
Q

Long-term preservation of RBC units with rare phenotype or autologous RBC units

A

FROZEN DEGLYCEROLIZED RBCS

21
Q

Alternative to CMV-seronegative units in
emergencies

A

FROZEN DEGLYCEROLIZED RBCS

22
Q

Decreases febrile transfusion reactions

A

FROZEN DEGLYCEROLIZED RBCS

23
Q

mL of FROZEN DEGLYCEROLIZED RBCS

A

250 mL

24
Q

Shelf life of FROZEN DEGLYCEROLIZED RBCS

A

10 years at -65°C to -200°C
24 hours at 1-6°C after washing (AG:40% glycerol)

25
Q

Decreases risk of alloimmunization to HLA antigens on leukocytes

A

LEUKOCYTE-REDUCED RBCS

26
Q

Decrease febrile non-hemolytic transfusion reactions

A

LEUKOCYTE-REDUCED RBCS

27
Q

Reduce the risk of CMV infection

A

LEUKOCYTE-REDUCED RBCS

28
Q

Decrease immunomodulation, and may decrease the risk of prion transmission in B lymphocytes

A

LEUKOCYTE-REDUCED RBCS

29
Q

3 log filtration

A

LEUKOCYTE-REDUCED RBCS

30
Q

Two RBC is divided into two separate RBC units of equal volume

A

TWO-UNIT RBCS, APHERESIS

31
Q

Similar to pRBC (increase oxygen carrying capacity)

A

TWO-UNIT RBCS, APHERESIS

32
Q

Volume of TWO-UNIT RBCS, APHERESIS

A

320 ml

33
Q

Shelf life of TWO-UNIT RBCS, APHERESIS

A

1 year at 1-6 °C

34
Q

Bleeding due to quantitative and qualitative platelet disorders

A

RANDOM DONOR PLATELET CONCENTRATE

35
Q

Prophylaxis in severely thrombocytopenic patients (5,000 – 10,000/uL)

A

RANDOM DONOR PLATELET CONCENTRATE

36
Q

Volume of RANDOM DONOR PLATELET CONCENTRATE

A

50 - 70 mL

37
Q

Shelf life of RANDOM DONOR PLATELET CONCENTRATE

A

5 days at 20-24 °C with constant gentle agitation & 4 hours after pooling

38
Q

Platelets in approx. 250ml of plasma to maintain pH above 6.2

▪ Indications, similar to random donor platelets

A

PLATELETS, PHERESIS (SINGLE DONOR PLATELETS)

39
Q

Volume of PLATELETS, PHERESIS (SINGLE DONOR PLATELETS)

A

200 - 400 ml

40
Q

Shelf life of PLATELETS, PHERESIS (SINGLE DONOR PLATELETS)

A

5 days at 20-24°C with constant gentle agitation

41
Q

3rd gen filter

A

LEUKOCYTE REDUCED PLATELETS

42
Q

Bedside filtration is done immediately before transfusion (3log filters)

A

LEUKOCYTE REDUCED PLATELETS

ISBB!!!! (24 decks)

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