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Flashcards in Blood Pressure Deck (20):
1

Which cells release renin?

Granular cells in the juxtaglomerular apparatus

2

which cells monitor Na levels in tubular fluid?

macula densa

3

which 3 things stimulate renin release ?

renal artery hypotension (systemic hypotension)
stimulation of renal sympathetic nerves
Decreased Na in renal tubular fluid sensed by macula dense cells

4

Two types of Natriuretic peptides?

ANP and BNP

5

Where are the 2 peptides produced?

ANP in the atria, BNP in the ventricles

6

What system do the natriuretic peptides counteract?

RAAS

7

When are NPs released and what do they do?

released in response to cardiac distension and cause excretion of salt and water in the kidneys. Also act as vasodilators, reducing blood pressure.

8

Serum ___ can be measured in patients with suspected heart failure?

BNP

9

ADH is also known as?

vasopressin

10

ADH produced in ?

hypothalamus

11

here is ADH stored?

posterior putuitary (pp)

12

secretion of ADH is stimulated by?

Reduced extracellular fluid volume (INCREASED PLASMA OSMOLALITY)

13

extracellular fluid volume is sum of 2 components - what are they?

Intracellular fluid and plasma. Cells bathe in solution

14

Where is ACE enzyme found mainly?

pulmonary vasccular endothelium

15

what does renin do?

stimulates formation of angiotensin I from angiotensinogen

16

where is angiotensinogen produced

liver

17

where is aldosterone released?

adrenal cortex

18

where does it act?

on kidney

19

what is the effect of aldosterone?

it causes water and sodium retention

20

what do NPs do simply?

cause vasodilation and cause sodium and water excretion