Blood Transfusion And Blood Groups

Question 1

Blood collecting bag called as

Answer 1

CHITRA BAG

Question 2

Ratio of blood volume and Anticoagulant solution

Answer 2

50:7 ratio
Example - 350ml Blood + 49ml Anticoagulant solution

Question 3

Anticoagulant solutions

Answer 3

ACD - Acid citrate dextrose
CPD - Citrate phosphate dextrose
CPD-A - Citrate phosphate dextrose - Adenine
SAGM - Saline adenine glucose mannitol, Citrate/phosphate

Question 4

Shelf life of blood

Answer 4

ACD - 21 Days
CPD - 21 Days
CPD-A - 35 Days
SAGM - 42 days - preferred chemical

Question 5

Whole blood shelf life

Answer 5

Depends on added anticoagulant
Maximum 42 Days when added with SAGM

Question 6

Whole blood stored at what temperature

Answer 6

2-6°C

Question 7

Packed RBC Shelf life and storing temperature

Answer 7

21-49 days
Temp. 2-6°C

Question 8

Platelets shelf life

Answer 8

5 days

Question 9

Platelets stored at temp.

Answer 9

20-24°C

Question 10

Fresh frozen plasma shelf life and temperature

Answer 10

1 year
-18°C

Question 11

Cryoprecipitate shelf life and storing temperature

Answer 11

1 year
-18°C

Question 12

Cryoprecipitate contains

Answer 12

vWF, Factor Viii, Xiii and Fibrinogen

Question 13

Fresh frozen plasma contains

Answer 13

All clotting factors except vWF, factor 8,13 and Fibrinogen

Question 14

Whole blood transfusion needs in case of

Answer 14

Massive blood transfusion
Exchange blood transfusion

Question 15

Packed RBC transfusion in case of

Answer 15

Severe anemia
Prevents fluid overload

Question 16

Platelet transfusion in case of

Answer 16

Thrombocytopenia

Question 17

Fresh frozen plasma in case of

Answer 17

Burns - if fluid loss
Clotting factors deficiency

Question 18

Cryoprecipitate transfusion in case of

Answer 18

In deficiency of vWF, CF 8, 13 and Fibrinogen

Question 19

Which component of whole blood is not necessary to be ABO Compatible

Answer 19

Cryoprecipitate

Question 20

Blood transfusion set consists of

Answer 20

Transfusion needle - 18-19gauge
Micropore filter - 170-200micron

Question 21

Whole blood transfusion should be started within after taking out from blood bank

Answer 21

Within 30 minutes and finish within 4 hours

Question 22

Fresh frozen plasma and Cryoprecipitate should be transfused within

Answer 22

ASAP and should be finished within 20 minutes

Question 23

Complications during blood transfusion in donor

Answer 23

Bruise or hematoma on injection site
Vasovagal syncope
Local site complications
Hypocalcemia (due to citrate) - Perioral numbness and tingling sensation

Question 24

How to prevent donor complications during blood transfusion

Answer 24

Slow infusion
Oral calcium

Question 25

Complications in recipients during transfusion

Answer 25

Fever Acute hemolytic transfusion reaction Allergic reactions TRALI Post transfusion purpura GVHD Infections

Question 26

Fever in receipents during blood transfusion can be due to

Answer 26

Febrile non hemolytic transfusion reaction (FNHTR) Most common Blood transfusion reaction

Question 27

Fever in receipents during blood transfusion can be due to

Answer 27

Febrile non hemolytic transfusion reaction (FNHTR) Most common Blood transfusion reaction

Question 28

Acute Hemolytic transfusion reaction also known as

Answer 28

Mismatch blood transfusion

Question 29

Mismatching is mostly due to

Answer 29

Clerical error

Question 30

Clinical symptoms in mismatching

Answer 30

Fever +++ Abdominal/flank pain Hemoglobinuria

Question 31

Management of Mismatching blood transfusion

Answer 31

Stop blood transfusion immediately Iv acess + - Give normal saline Send blood sample of patient and blood bag to check once again

Question 32

Sign of Mismatching blood transfusion in anesthetic or unconscious patient

Answer 32

Oozing from venipuncture site Fever

Question 33

Most common allergic reaction during blood transfusion

Answer 33

Anaphylaxis - Type 1 HR High risk in IgA deficiency patient

Question 34

TRALI Full form

Answer 34

Transfusion associated acute lung injury

Question 35

TRALI Happens

Answer 35

Within 6 hours after giving Fresh frozen plasma

Question 36

TRALI Pathogenesis

Answer 36

It happens when donor antibodies agglutinates with recipients antibodies - these WBCs goes to lungs - increases lungs permeability - can lead to Non cardiogenic pulmonary edema

Question 37

Post transfusion purpura is seen in case of

Answer 37

Platelets transfusion Usually seen after 7-10 days

Question 38

GVHD Full form

Answer 38

Graft versus host disease

Question 39

GVHD usually seen in

Answer 39

Immunocompetent donor T cells Within 8-10 days

Question 40

Infections are seen most commonly in

Answer 40

Platelet transfusion

Question 41

Massive blood transfusion means

Answer 41

If blood volume (5L) given within 24 hours Or More than 50% of blood volume given within 3 hours

Question 42

Complications of Massive blood transfusion

Answer 42

1) Hypothermia 2)Electrolyte disturbances - Hyperkalemia , Hypocalcemia and Metabolic alkalosis 3) Dilutional coagulopathy