BM : DNA, RNA Flashcards
(38 cards)
What are nucleic acids
Polymers made form nucleotides
what are the 2 types of nucleic acids
- DNA
- RNA
What does DNA stand for?
DeoxyriboNucleic Acid
Where is DNA found
All organisms
- plants
- microorganisms
- animals
What does DNA carry
Genes
what are genes
Sections of DNA that code for a protein
what are all organisms built of?
Proteins
What are the building blocks of DNA
DNA nucleotide
What are DNA nucleotides made of
- phosphate
- deoxyribose sugar
- nitrogenous base
how many types of nucleotides are there and whats different about them
4
- each has different base : adenine, thymine, cytosine, and guanine
What is the structure of DNA
DNA double helix
- join nucleotides by condensation reaction between sugar and phosphate to form a polynucleotide
- join two polynucleotides by hydrogen bonds between the bases
- A joins T, C joins G (complementary base pairing(
- produces double stand (anti-parallel)
- then coil double strand into helix
DNA structural properties : Double stranded
Makes DNA more stable
- 2 strands act as templates in semi- conservative replication
DNA structural properties : Coil in DNA
more compact
What are the DNA structural properties
- double stranded
- coil in DNA
- sugar-phosphate backbone
- hydrogen bonds between bases
- complementary base pairing
DNA structural properties : sugar phosphate backbone
protects bases
DNA structural properties : hydrogen bonds between bases
weak. so double strand separates more easily for semi-conservative replication
DNA structural properties : complementary base pairing
ensures identical copies of DNA made by semi-conservative replication
When does DNA replication occur?
in interphase before mitosis and meiosis
How does DNA replication occur
By semi-conservative replication
Basics of semi-conservative replication occur?
- DNA double strand separate
- act as templates
- producing 2 identical copies of the DNA
- each has half the original strand
- and half the new strand
Process of semi-conservative DNA repilcation
- DNA helicase breaks hydrogen bonds between the complementary bases
- double strands separate, leaving 2 template strands
- free complementary nucleotides bind to exposed bases on the template strands
- DNA polyemerase joins the sugar-phosphate backbone of the new strand
Evidence for semi-conservative replication
- replicating bacterial DNA in 2 types of nitrogen isotopes
Two nitrogen isotopes used in semi-conservative replication
15N = heavy isotope 14N = light isotope
Where is the nitrogen found in semi-conservative replication
in nitrogenous bases of DNA