BMS 107 Blood Flashcards

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0
Q

Describe the 3 main components of blood. what is hematocrit and how is it determined? What are the normal female and male values?

A

Plasma, erythrocytes and buffy coat; Hematocrit is the % of the red blood cells in one’s blood; Females - 38% - 46%, males 42% - 56%

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1
Q

What are the functions of blood?

A
  1. Transportation (O2, CO2 and nutrients)
  2. Regulation (temperature, Ph level, total body fluid volume)
  3. Protection (immune response, white blood cells)
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2
Q

What are the components of plasma? What protein is found in highest concentration in blood plasma?

A

Water, proteins and other solutes; Albumins are the most common protein found in plasma

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3
Q

How are red blood cells different from “normal” cells?

A

Mature red blood cells lack nuclei and other organelles.

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4
Q

Why do red blood cells have a biconcave shape?

A

It increases surface area

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5
Q

What molecule inside red blood cells allows them to carry O2 and CO2?

A

Hemoglobin

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6
Q

What is the structure of hemoglobin?

A

Hemoglobin consists of four globin protein molecules.

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7
Q

What is erythropoesis and where does it occur?

A

The processes of erythrocyte (red blood cell) production; made in red bone marrow

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8
Q

Where do red blood cells go to die?

A

The spleen and liver

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9
Q

Where is recycled iron stored?

A

Liver

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10
Q

How long are red blood cells in the blood stream? Why don’t they last longer?

A

120 days; no organelles to repair them

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11
Q

What is bilirubin?

A

A component of a digestive secretion called bile, which is produced by liver cells. Made from broken down heme.

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12
Q

What are the function of white blood cells?

A

They help initiate an immune response and defend the body against pathogens.

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13
Q

Define chemotaxis and diapedesis as they relate to white blood cells.

A

Chemotaxis: follows chemicals to move

Diapedesis: leaves the blood vessels to the intercellular fluid

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14
Q

Describe Neutorphils.

A

Granulocytes, make up 65% of white blood cells, increase in number during infections, use phagocytosis.

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15
Q

Describe Lymphocytes.

A

Agranulocytes; T-cells and B-cells; secrete antibodies

16
Q

Describe Monocytes.

A

Agranulocytes; use phagocytosis; called macrophages in CT

17
Q

Describe Eosinophils.

A

Granulocytes; phagocytosis of antibody antigen complexes and allergens

18
Q

Describe Basophils.

A

Granulocytes; more common in interstitial fluid; release histamine (causing vasodilation); releases heparin (decreases blood clotting); responsible for classic allergy symptoms

19
Q

Are platelets cells? What is their function?

A

No; help with blood clotting

20
Q

What are the basic components required for a blood clot?

A
Platelets
Fibrin
Erythrocytes (red blood cells)
Calcium
Vitamin K