BMS 108 Ch. 08 Central Nervous System Flashcards

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0
Q

What is the basal ganglia?

A

Distinct masses of cell bodies located deep inside cerebrum plus some midbrain structures.

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1
Q

The _____ _____ is a collection of brain regions crucial for emotions.

A

limbic system

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2
Q

What is another name for basal ganglia?

A

basal nuclei

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3
Q

What is the function of the basal ganglia?

A

Its function is to control voluntary movement, although ultimate commands come from motor cortex.

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4
Q

In the basal ganglia, dopamine projections extend from the midbrain to the __________.

A

forebrain

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5
Q

Basal ganglia have reciprocal excitatory connections with the cerebral cortex that create a _______ _______.

A

motor circuit

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6
Q

Which collection of nuclei use dopamine to help regulate motor control?

A

Basal ganglia

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7
Q

Damage to the basal ganglia is associated with what two diseases?

A

Parkinson’s and Huntington’s disease

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8
Q

What are the two types of dopamine neurons in the basal ganglia?

A

Motor and Mesolimbic

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9
Q

Motor dopamine neurons connect the _______ _______ to forebrain structures.

A

substantia nigra

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10
Q

Mesolimbic dopamine neurons originate in the _______ _______ _______ (VTA) and are involved in reward and addiction.

A

ventral tegmental area

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11
Q

What is a symtom of schizophrenia in the mesolimbic neurons of the basal ganglia?

A

too much dopamine

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12
Q

Can drug abuse cause dopamine release?

A

yes

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13
Q

What is a dendritic spine?

A

a projection from a dendrite that receives impulses from an axon.

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14
Q

What are the two types of memory?

A

short term and long term

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15
Q

How many items can you hold in short term memory?

A

7-9

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16
Q

What is consolidation?

A

Turning short term memories into long term memories.

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17
Q

What are the two types of long-term memory?

A

Declarative and non-declarative

18
Q

What is declarative long-term memory?

A

Verbal or statable memories

19
Q

What are non-declarative long-term memories?

A

Procedural memories; simple skills and conditioning.

20
Q

Amnesiacs have an impaired ________ memory.

A

declarative

21
Q

What are the two types of amnesia? What impact does each type have on memory?

A

Retrograde amnesia - trouble remembering the past (old memories)
Anterograde amnesia - trouble forming new memories

22
Q

What are the two brain structures most responsible for acquiring memories?

A

Hippocampus and amygdala

23
Q

What is the function of the hippocampus?

A

Acquire new memories and consolidation short-term memories into long-term memories.

24
Q

Where are memories stored?

A

In the cerebral hemispheres

25
Q

What is the mechanism of memory called?

A

Long-term potentiation (LTP)

26
Q

How does LTP make memories?

A

by strengthening the relationship between two neurons

27
Q

Describe the process of LTP.

A
  1. Glutamate binds to AMPA and NMDA receptors
  2. AMPA channels open, Na+ enters the postsynaptic cell
  3. Depolarization releases Mg++ block on the NMDA receptors
  4. NMDA channels open and Ca++ enters the cell
  5. Ca++ activates 2nd messenger system and causes 3 changes:
    A. leads to insertion of more AMPA receptors
    B. NO (Nitric Oxide) diffuses retrograde and increases glutamine release
    C. Postsynaptic Ca++ increases transcription, which increases the number of dendritic spines
28
Q

What is the most important structure for homeostasis?

A

hypothalamus

29
Q

What does the hypothalamus contains neural centers for?

A

Hunger
Thirst
Body Temp

30
Q

What does the hypothalmus regulate?

A
  1. Sleep
  2. Emotions
  3. Sexual arousal
  4. Anger
  5. Fear
  6. Pain
  7. Pleasure
31
Q

The hypothalamus is part of the _______ ________.

A

Limbic system

32
Q

The hypothalamus also has an intimate relationship with the _______ ______ of the endocrine system.

A

pituitary gland

33
Q

What is an Electroencephalogram (EEG)? What can you use it for?

A

A measurement of electrical activity of the brain; measures epilepsy and brain death; measures sleep and alertness states.

34
Q

What are the brain waves measured by an EEG the result of?

A

EPSPs & IPSPs

35
Q

What are four types of brain waves?

A

Alpha
Beta
Theta
Delta

36
Q

What are alpha waves?

A

brain waves present when awake, relaxed with eyes closed.

37
Q

What are beta waves?

A

“Evoked activity” brain waves produced by visual stimuli and mental activity. They respond to stimuli from receptors and are superimposed on the continuous activity patterns already present.

38
Q

What are theta waves?

A

A brain wave pattern common in newborns but if present in adults it is a sign of severe emotional stress and forewarns of a nervous breakdown.

39
Q

What are delta waves?

A

Occurs during non-REM sleep in adults and are present in awake infants. Presence in awake adults indicates brain damage.

40
Q

What are the two types of sleep?

A

REM and non-REM

41
Q

What is REM sleep?

A

Rapid Eye Movement; wave patterns look similar to awake ones; dreaming occurs during this type of sleep.

42
Q

What is non-REM sleep?

A

delta wave pattern; believed to be crucial for consolidation of short- into long-term memory.

43
Q

What are some characteristics of epilepsy?

A

abnormal, excessive or synchronous neural activity; frequent seizures.