BMS 127 Ch. 15 Innate Immunity Flashcards

0
Q

Mucus-secreting membranes are found in the

a. urinary system
b. digestive cavity
c. respiratory passages
d. all of the above

A

d. all of the above

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1
Q

Phagocytes of the epidermis are called

a. microglia
b. goblet cells
c. alveolar macrophages
d. dendritic cells

A

d. dendritic cells

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2
Q

The complement system involves

a. the production of antigens and antibodies.
b. serum proteins involved in nonspecific defense.
c. a set of genes that distinguish foreign cells from body cells.
d. the elimination of undigested remnants of microorganisms.

A

b. serum proteins involved in nonspecific defense.

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3
Q

The alternative complement activation pathway involves

a. factors B, D, and P
b. the cleavage of C5 to form C9
c. binding to mannose sugar
d. recognition of antigens bound to specific antibodies

A

a. factors B, D, and P

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4
Q

Complement must be inactivated because if it were not,

a. viruses could continue to multiply inside host cells using the host’s own metabolic machinery.
b. necessary interferons would not be produced.
c. protein synthesis would be inhibited, thus halting important cell processes.
d. it would make holes in the body’s own cells.

A

d. it would make holes in the body’s own cells.

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5
Q

The type of interferon present late in an infection is

a. alpha interferon
b. beta interferon
c. gamma interferon
d. delta interferon

A

c. gamma interferon

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6
Q

Interferons

a. do not protect the cell that secretes them.
b. stimulate the activity of macrophages.
c. cause muscle aches, chills and fever.
d. all of the above.

A

d. all of the above.

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7
Q

Which of the following is not targeted by a Toll-like receptor?

a. lipid A
b. eukaryotic flagellar protein
c. single-stranded RNA
d. lipoteichoic acid

A

b. eukaryotic flagellar protein

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8
Q

Toll-like receptors (TLRs) act to

a. bind microbial proteins and polysaccharides
b. induce phagocytosis
c. cause phagocytic chemotaxis
d. destroy microbial cells

A

a. bind microbial proteins and polysaccharides

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9
Q

The surface cells of the epidermis of the skin are _____.

A

dead

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10
Q

The surface cells of the mucous membranes are _______.

A

alive

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11
Q

Wandering macrophages experience __________.

A

diapidesis

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12
Q

__________ are immature macrophages.

A

Monocytes

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13
Q

_____________ are large agranulocytes.

A

Monocytes

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14
Q

___________ exhibit chemotaxis toward a pathogen.

A

Phagocytes

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15
Q

In phagocytosis, adherence involves the binding between complementary chemicals on a phagocyte and on the membrane of a ___________.

A

pathogen

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16
Q

_____________ occurs when a phagocyte’s pseudopodia surround a microbe and fuse to form a sac.

A

Ingestion

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17
Q

Lysosomes fuse with phagosomes to form ___________.

A

phagolysosomes

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18
Q

A membrane attack complex drills circular holes in a _____________.

A

pathogen

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19
Q

Rubor, calor, swelling, and dolor are associated with ____________.

A

inflammation

20
Q

Acute and chronic inflammation exhibit ________ signs and symptoms.

A

similar

21
Q

The _____________ of the brain controls the body’s temperature.

A

hypothalamus

22
Q

Defensins are ____________ __________ of the second line of defense.

A

antimicrobial peptides

23
Q

NETs are webs produced by ____________ to trap microbes.

A

neutrophils

24
Q

For the following term, what is the line of defense that first applies?

Inflammation

A

Second

25
Q

For the following term, what is the line of defense that first applies?

Monocytes

A

Second

26
Q

For the following term, what is the line of defense that first applies?

Lactoferrin

A

Second

27
Q

For the following term, what is the line of defense that first applies?

Fever

A

Second

28
Q

For the following term, what is the line of defense that first applies?

Dendritic cells

A

First

29
Q

For the following term, what is the line of defense that first applies?

Alpha interferon

A

Second

30
Q

For the following term, what is the line of defense that first applies?

Mucous membrane of the digestive tract

A

First

31
Q

For the following term, what is the line of defense that first applies?

Neutorphils

A

Second

32
Q

For the following term, what is the line of defense that first applies?

Epidermis

A

First

33
Q

For the following term, what is the line of defense that first applies?

Lysozyme

A

First

34
Q

For the following term, what is the line of defense that first applies?

Goblet cells

A

First

35
Q

For the following term, what is the line of defense that first applies?

Phagocytes

A

Second

36
Q

For the following term, what is the line of defense that first applies?

T lymphocytes

A

Third

37
Q

For the following term, what is the line of defense that first applies?

Antimicrobial peptides

A

First

38
Q

For the following term, what is the line of defense that first applies?

Sebum

A

First

39
Q

What does a goblet cell do?

A

Secrete mucus

40
Q

What does a lysozyme do?

A

Breaks bonds in bacterial cell walls

41
Q

What is a stem cell?

A

A generative cell with many types of offspring

42
Q

What does a dendritic cell do?

A

Devours pathogens in the epidermis

43
Q

Where are formed elements (platelets) developed?

A

In bone marrow

44
Q

What is an eosinophil?

A

A leukocyte that primarily attacks parasitic worms

45
Q

What is the phagocytic cell in the lungs called?

A

Alveolar macrophage

46
Q

What is a microglia?

A

A phagocytic cell in the CNS

47
Q

Wandering macrophages are _____________ scavengers.

A

Intercellular

48
Q

List the 6 steps in phagocytosis.

A
  1. Chemotaxis of the phagocyte to the pathogen
  2. Adherence
  3. Ingestion of the microbe by the phagocytes
  4. Fusion of a series of vesicles including lyosomes
  5. Killing of the microbe with enzymes and other chemicals
  6. Elimination (exocytosis)