BMS 127 Ch. 22 Pathogenic Fungi Flashcards

0
Q

Of the following fungi, which is usually transmitted from person to person?

a. Blastomyces dermatitidis
b. Coccidiodes immitis
c. Tricophyton rubrum
d. Aspergillus fumigatus

A

c. Tricophyton rubrum

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1
Q

A fungus that can infect both healthy and immunocompromised patients is called

a. true pathogen.
b. an opportunistic pathogen.
c. a commensal organism.
d. a symbiotic organism.

A

a. true pathogen.

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2
Q

Which of the following is not used to identify true fungal pathogens?

a. growth at 25 degrees C and 37 degrees C to show dimorphism
b. GMS staining of infected tissues
c. serological testing
d. clinical symptoms alone

A

d. clinical symptoms alone

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3
Q

Because amphotericin B is extremely toxic to humans, most clinicians prescribe it only for

a. dermatophyte infections.
b. Malassezia infections.
c. systemic infections.
d. black peidra

A

c. systemic infections.

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4
Q

Ringworm is caused by

a. helminth
b. dermatophyte
c. dimorphic fungus
d. commensal fungus

A

b. dermatophyte

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5
Q

Which of the following is considered a classical opportunistic fungus?

a. Piefraia hortae
b. Histoplasma capsulatum
c. Fonsecaea pedrosoi
d. Aspergillus niger

A

d. Aspergillus niger

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6
Q

Subcutaneous infections tend to be acquired through

a. inhalation and remain localized.
b. inhalation and become systemic.
c. trauma and remain localized.
d. trauma and become systemic.

A

c. trauma and remain localized.

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7
Q

The term dermatophyte refers to

a. pathogenicity.
b. where a fungus grows.
c. method of spread.
d. pigmentation.

A

b. where a fungus grows.

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8
Q

Which of the following subcutaneous mycoses may exhibit respiratory and cerebral forms?

a. chromoblastomycosis
b. mycetoma
c. phaeohyphomycosis
d. sporotrichosis

A

c. phaeohyphomycosis

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9
Q

Which of the following systemic mycoses is endemic to the deserts of the southwestern United States?

a. blastomycosis
b. coccidioidomycosis
c. histoplasmosis
d. paracoccidioidomycosis

A

b. coccidioidomycosis

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10
Q

A spherule stage is seen in humans infected with what organism?

a. Blastomyces dermatitidis
b. Coccidiodes immitis
c. Histoplasma capsulatum
d. Paracoccidiodes brasiliensis

A

b. Coccidiodes immitis

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11
Q

Of the following fungal diseases, which is found in almost all terminal AIDS patients?

a. chromoblastomycosis
b. blastomycosis
c. candidiasis
d. peidra

A

c. candidiasis

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12
Q

Which of the following predisposing factors would leave a patient with the greatest long-term risk of acquiring a fungal infection?

a. invasive medical procedures
b. AIDS
c. chronic illness such as diabetes
d. short-term treatment with antibacterial agents

A

b. AIDS

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13
Q

Fungal allergens generally stimulate what type of reaction?

a. type I hypersensitivity
b. type II hypersensitivity
c. type III hypersensitivity
d. type IV hypersensitivity

A

a. type I hypersensitivity

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14
Q

A pathogenic feature of Cryptococcus neoformans is

a. production of destructive enzymes
b. production of a capsule
c. infection of immune cells
d. variation of surface antigens to avoid immune system recognition

A

b. production of a capsule

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15
Q

The most common manifestation of Cryptococcus infection in AIDS patients is

a. blindness
b. cutaneous infection
c. meningitis
d. pneumonia

A

c. meningitis

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16
Q

Bread mold can cause which disease?

a. aspergillosis
b. dermatophytosis
c. mycetoma
d. zygomycosis

A

d. zygomycosis

17
Q

Mycetismus is caused by

a. inhalation of fungal allergens
b. ingestion of mushrooms
c. traumatic inoculation o fungi beneath the skin
d. close contract with infected individuals

A

b. ingestion of mushrooms

18
Q

One of the more poisonous mycotoxins is produced by

a. Amantia phalloides
b. Amantia muscauria
c. Psilocybe cubensis
d. Claviceps purpurea

A

a. Amantia phalloides

19
Q

The number of mycoses worldwide is rising, in part, because

a. the number of fungi in the environment is rising.
b. the number of immunocompromised individuals in the population is rising.
c. fungi have become more pathogenic.
d. fungi are developing a tendency to be spread from person to person.

A

b. the number of immunocompromised individuals in the population is rising.

20
Q

Fungi are generally ____________ from person to person.

A

not transmitted

21
Q

On the whole, fungal infections relatively ______ to treat.

A

difficult

22
Q

___________ are always contracted from the environment.

A

Systemic mycoses

23
Q

Chromoblastomycosis and phaeohyphomycosis are both caused by ________ ascomycetes.

A

dark-pigmented

24
Q

_____________ is always caused by traumatic introduction of fungi beneath the skin.

A

Sporotrichosis

25
Q

Coccidiodomycosis does not occur normally outside the _______ _________.

A

Western Hemisphere

26
Q

Treatment of individuals with broad spectrum antibacterial agents is a predisposing factor for __________ fungal infections.

A

opportunistic

27
Q

Candida albicans generally causes localized opportunistic infections but can become systemic, particularly in the __________.

A

immunocompromised

28
Q

Relapse of fungal diseases in common in ______ patients.

A

AIDS

29
Q

_______ % of individuals have alllergies to fungal elements.

A

3-10

30
Q

Dimorphic fungi exist as ________ forms in the environment and as ________ forms in their hosts.

A

mycelial; yeast

31
Q

What are the four true fungal pathogens?

A
  1. Blastomyces dermatitidis
  2. Coccidiodes immitis
  3. Histoplasma capsulatum
  4. Paracoccidiodes brasiliensis
32
Q

Many anti-fungal agents target the compound _______ in fungal cytoplasmic membranes.

A

ergosterol

33
Q

_________ piedra is characterized by hard nodules on the hair shaft, whereas ________ piedra is characterized by soft nodules.

A

Black; white

34
Q

Sporotrichosis is caused b the traumatic introduction of ____________ __________ into the skin (genus and species).

A

Sporothrix schenckii

35
Q

Which systemic mycosis is associated with bird droppings?

A

Cryptococcus neoformans

36
Q

What are the five most common agents of fungal opportunistic infections?

A
  1. Aspergillis
  2. Cryptococcus
  3. Candida
  4. Pneumocystis
  5. Mucor
37
Q

What is thrush caused by?

A

Candida albicans

38
Q

Pneumocystis was once classified as a ____________, but no it is classified as a ____________.

A

protozoan; fungus

39
Q

Ergot alkaloids are produced by some strains of the genus ___________.

A

Claviceps