BMS240 Objectives Flashcards Preview

Pharmacy > BMS240 Objectives > Flashcards

Flashcards in BMS240 Objectives Deck (47)
Loading flashcards...
1

1.1 Describe a basic cell type and basic chromosomal structure

.

2

1.2 Describe the cell cycle

.

3

1.3 Describe mitosis and meiosis

.

4

1.4 Understand the genetic significance of each process

.

5

1.5 Understand the two mechanisms that produce genetic variation during meiosis

.

6

1.6 Understand the importance of mitosis and meiosis for humans and human disease

.

7

1.7 Describe and explain Mendel’s laws using examples

.

8

1.8 Understand the terms genotype, phenotype and associated nomenclature

.

9

1.9 Apply the checkerboard/punnet square method for predicting offspring in a monohybrid ad dihybrid cross

.

10

2.1 Understand the differences between the X chromosome and the Y chromosome in mammals

.

11

2.2 Define the terms Kleinfelter, Turner, sex linked characteristics, X linked characteristics, Y linked characteristic, hemizygous, non disjunction, lyonisation and dosage compensation

.

12

2.3 Describe the principle of lyonisation and its effect on the mammalian phenotype

.

13

2.4 Understand the function of dosage compensation and describe the various ways dosage compensation is achieved

.

14

2.5 Understand and describe in detail how dosage compensation is achieved in humans

.

15

2.6 Define and describe the factors that complcate the pasic principles of genetics: co-dominance, penetrance, expressivity, sex influence and sex limited characteristics, anticipation and interaction between genes and envrioment

.

16

2.7 Describe in detail one example of all of the above mentioned factors, using Bombay phenotype for recessive epistasis

.

17

2.8 Define and explain using an example the following terms: cytoplasmic inheritance, genetic maternal effect, genomic imprinting, epigenesis, phenocopy and continuous trait

.

18

3.1 Define and describe the terms pedigree, concordance, karyotype and consanguinity

.

19

3.2 Understand the use ad construction of pedigrees and how they can be analysed

.

20

3.3 Analyse simple pedigrees with respect to types of inheritance

.

21

3.4 Describe in detail autosomal dominant, autosomal recessive, X linked dominant, X linked recessive and Y linked inheritance patterns

.

22

3.5 Understand and describe the role of twin studies in genetics

.

23

3.6 Understand the methods used in genetic screening

.

24

3.7 Understand genetic counselling and genetic testing and the ethics involved

.

25

3.8 Understand the types of genetic testing and the indicators used for each type

.

26

3.9 Know two examples of human genetic disease that would lead to the recommendation of genetic testing

.

27

4.1 Understand the concept of linked genes

.

28

4.2 Understand and contrast the terms recombinant gamete and non recombinant gamete

.

29

4.3 Understand the importance of the chromosomal location of a gene in linkage studies

.

30

4.4 Describe how the concept of linkage can be used for human gene mapping

.