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Bone Flashcards

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1
Q

Identify 1-3.

A
  1. compact bone
  2. periosteum
  3. spongy bone (diploe)
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1
Q

large multinucleated motile cells, remove/resorb bone, forms from fusion of many monocytes, secrete enzymes that degrade bone, have ruffled border

A

osteoclast

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2
Q

Identify 1-3.

A
  1. epiphysis
  2. metaphysis
  3. diaphysis
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2
Q

these cells are responsible for secretion of organic component of bone, important for signaling for calcification of bone, found on surface of bone matrix, lots of RER

A

osteoblasts

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2
Q

part of osteon that contains vasculature

A

central canal aka Havershon’s canal

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2
Q

Identify.

A

cement line

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3
Q

fills in spaces between osteons, made of remnants of old osteons

A

interstitial lamellae

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3
Q

Identify what is marked with *

A

inner circumferential lamellae

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3
Q

This type of bone does not contain osteons.

A

spongy/trabecular bone

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4
Q

Identify.

A

osteons

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5
Q

where is spongy bone laid down?

A

along stress lines, found more internally in a bone

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6
Q

osteoblasts produce ___, the organic portion of ECM made up of type 1 collagen

A

osteoid

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6
Q

type of collagen present in lamellae of osteon?

how is it arranged?

A

type 1

run parallel to each other, at angle (next lamellae fibers run at 90 degree angle to previous lamellae fibers)

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6
Q

Identify 1-5.

A
  1. adipocytes
  2. osteocyte
  3. endosteum
  4. periosteum
  5. muscle
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7
Q

covers the outer surface of the bone, is vascularized, contains osteoprogenitor cells.

A

periosteum

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9
Q

long axis of bone- contains medullary cavity in center, has compact bone on outside

A

diaphysis (aka shaft)

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10
Q

___ lay down bone ____ break down bone

A

osteoblasts osteoclasts

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12
Q

main difference between woven & lamellar bone?

A

woven bone has collagen fibers in random directions, lower mineral content, more osteocytes

lamellar bone is collagen fibers parallel in rings, is well-organized, fewer osteocytes

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12
Q

Type of bone?

A
  1. woven bone
  2. lamellar bone
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12
Q

outer limit of each osteon, where it is very collagen rich

A

cement line

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13
Q

these cells are mesenchymal stem cells that can differentiate into osteoblasts, found in periosteum & endosteum

A

osteogenic cell

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14
Q

consists of cells that belong to stroma of marrow, main source of lining cells of haversian canals

A

endosteum

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15
Q

these sit in lacuna between lamellae of osteon

A

osteocytes

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16
Q

bone spicules present in spongy bone

A

trabeculae

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18
cortical bone = ____ trabecular bone = \_\_\_\_
compact bone spongy bone
19
Identify 1-3.
1. Haversian canal (central canal) 2. Volkmann's canal 3. Sharpey's fibers
20
Type of bone?
woven
21
this area of osteoclast helps prevent H ions from ruffle border from leaking out
sealing zone
22
where do osteoblasts sit in trabeculae?
along outside
24
these perforate the periosteum to supply the compact bone of a long bone
Sharpey's fibers
26
type of cartilage found on ends of long bone
hyaline
26
Type of bone?
lamellar bone
27
Identify 1-2.
1. cannaliculi 2. osteocytes (in lacunae)
28
connect central canal of osteon to endosteum and periosteum
Volkmann's canals
29
this area of long bone lengthens as you grow (separates the metaphysis & epiphysis)
epiphyseal plate
29
this lines the trabecullae of inner bone
endosteum
30
Type of bone?
woven/immature
32
functions of bone?
protection support mechanical basis for movement storage blood cell formation
33
end part of long bone
epiphysis
33
fibrous outer layer of periosteum is where ___ attachment occurs
muscle
34
flared out portion between diaphysis & epiphysis
metaphysis
35
direction of movement of nutrients in a trabeculae?
from outside to inside
36
these cells are totally surrounded by ECM, stuck in lacuna, cytoplastmic extensions for communication and nutrient passage, maintains the bone tissue that is present
osteocyte
37
Identify.
epiphyseal line
40
primary bone tissue is \_\_\_\_ secondary bone tissue is \_\_\_\_
woven bone (immature bone) lamellar bone (mature bone)
41
Type of bone in 1-2?
1. Compact bone (cortical bone) 2. Spongy bone (cancellous bone)
43
Type of bone?
lamellar
45
shapes of bone?
long (shaft w/ 2 ends) short (cubed bones- ie tarsal, carpal bones) flat (ie skull, scapula) irregular (ie vertebrae) sesamoid (found in tendons ie patella)
46
Identify 1-3.
1. Havershon's canal (central canal) 2. Lamellae 3. Interstitial lamellae
48
Identify 1-2.
1. osteoblast 2. osteocyte
49
Indentify what is marked with \* What is arrow pointing to?
Outer circumferential lamellae Periosteum
50
these cells can give rise to both osteoblasts & osteoclasts
osteogenic cells
51
part of osteon that surrounds central canal- concentric rings of bone matrix
lamellae
52
Spongy bone is a type of ___ bone
lamellar (secondary)
53
structural unit of compact bone
osteon
54
Identify cell type.
osteoclast
55
Identify 1-3.
1. Osteoblasts 2. Osteons 3. Havershon's Canal (central canal)
56
extensions of osteocytes used for nutrient transfer are called...
cannaliculi
57
the inorganic portion of ECM that gives the bone its hardness is \_\_\_\_
hydroxyapetite crystals
59
toward end of puberty, hyaline cartilage disappears and is replaced with bone, so you are left with remnant called...
epiphyseal line
60
these connect 1 cannaliculi to the next to pass nutrients
gap junctions
61
2 main components of hydroxyapetite crystals
Ca & P
62
Identify cell type.
osteoclast
63
boundary between __ &\_\_\_ is where marrow cavity begins in a long bone
metaphysis & diaphysis
64
Identify 1-2.
1. osteoblast 2. osteoclast
66
Identify 1-2.
1. Osteoblast (lots of RER) 2. osteoid
67
Identify 1-5.
1. interstitial lamellae 2. outer circumferential lamellae 3. Volkmann's canal 4. osteon 5. central canal/ Havershon's canal
68
these lamellae go around the whole outside surface
outer circumferential lamellae

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