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Integumentary System Flashcards

1
Q

4 types of cells found in skin?

A

Keratinocytes Melanocytes Langerhans cells Merkel cells

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1
Q

Main cells of the skin- connected to each other via desmosomes

A

keratinocytes

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2
Q

type of secretion of eccrine & apocrine sweat glands?

A

maracrine- release through exocytosis into lumen, which leads to duct, which goes to surface

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3
Q

where are blood vessels of skin found?

A

in dermis (dense CT)

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4
Q

epidermis is derived from ___ & dermis is derived from ___

A

ectoderm mesoderm

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4
Q

type of skin?

A

thin skin

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5
Q

Oval structure that looks like cut onion. Deep in reticular dermis. Concentric rings of Schwann cells. Detects coarse touch.

A

Pacinian corpuscle

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6
Q

Layer?

A

Stratum granulosum

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7
Q

As keratinocytes move toward surface, pH becomes…

A

more acidic (desmosomes break down, cells slough off)

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8
Q

2 types of sudoriferous (sweat) glands?

A

eccrine & apocrine

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8
Q

these glands are important in thermoregulation- they dissipate heat, cool blood

A

eccrine

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9
Q

glands found everywhere EXCEPT thick skin. branched acinar cells, holocrine secretion, produce serum that softens skin

A

sebaceous (oil) glands

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9
Q

Identify.

A

Hair follicle

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10
Q

how is secretion of apocrine gland different from secretion of eccrine gland?

A

apocrine secretion is more thick, protein rich- results in body odor

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11
Q

what is largest organ in the body?

A

skin

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12
Q

Deepest layer of skin? (Both thin & thick)

A

stratum basale

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12
Q

mechanism of secretion for sebaceous glands?

A

holocrine- cell gets larger until it ruptures, cell dies with secretion

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13
Q

Shape of melanocytes?

A

rounded cell bodies with irregular cytoplasmic extensions

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13
Q

superficial layer of dermis? deep layer of dermis?

A

papillary layer reticular layer

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14
Q

glands confined to skin of axilla & peritoneal regions, develop in response to sex hormones, very large lumen, secrete onto hair follicle that then leads to surface

A

apocrine

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16
Q

superficial layer of skin? deep layer of skin?

A

epidermis dermis

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17
Q

layers of thick skin?

A

Stratum basale Stratum spinosum Stratum granulosum Stratum lucidum Stratum corneum

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18
Q

Identify.

A

Tonofibrils

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19
Q

elongates keratinized structures derived from invaginations of epithelium (only associated with thin skin)

A

hair follicles

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20
Thin transparent layer of skin- can't see edges of cells. No nuclei or granules.
stratum lucidum
20
Where are Langerhans cells found?
stratum spinosum
20
Identify.
nail
22
Cells undergoing mitosis are found in this skin layer
stratum basale
23
pigment producing cells of the skin
melanocytes
24
Shape of cells found in stratum basale?
cuboidal
25
Layer?
stratum corneum
25
Identify.
Sudiferous (sweat) glands
27
Detect light touch- contain elliptical sensory receptors. Found in dermal papillae
Meissner corpuscles
27
Layer?
stratum lucidum
28
Flattened "cortified" cells with no nucleus where cells are sloughing off
stratum corneum
30
Cells that protect nucleus of keratinocytes from sunlight?
melanocytes
32
Epidermal stem cells, melanocytes, and Merkel cells are all found in this skin layer
stratum basale
34
Granules of stratum granulosum contain...
keratohyaline
35
Cell Type?
Melanocyte
37
Keratins bind together to form these intermediate filaments which terminate at desmosomes
tonofibrils
38
antigen presenting cells of the skin
Langerhans cells
39
found in dermis- connected to hair follicles, made up of smooth muscle tissue that connects hair follicle to dermal papillary layer, causes hair shafts to pull/stand up on end
arrector pili muscles
41
hair is present in which type of skin?
thin skin
43
Tactile epithelial cells important for sensory reception of touch?
Merkel cells
44
what is integumentary system comprised of?
skin hair nails sweat glands oil glands
45
Identify both.
Eccrine sweat gland (left) Apocrine sweat gland (right)
46
layer deep to the skin
hypodermis (aka subcutaneous layer)
47
When stained with H&E, stratum lucidum stains very...
pink
48
layers of thin skin?
Stratum basale Stratum spinosum Stratum granulosum Stratum corneum
49
Cell Type?
Merkel cell
50
layer that is present in thick skin but not thin skin?
stratum lucidum
51
Most superficial layer of skin? (Both thin & thick)
stratum corneum
52
Identify.
Apocrine sweat gland
53
Identify 1-2.
1. Papillary layer of dermis 2. Reticular layer of dermis
55
flexible plates of keratin
nail
56
Thin skin has __ layers while thick skin has __ layers
4 5
57
Identify.
Sebacious (oil) gland
58
Oval-shaped cells containing lipids are found in this layer to make skin waterproof
stratum granulosum
59
What type of filament is keratin?
intermediate filament
60
Layer?
stratum corneum
61
type of skin?
thick skin
62
Layer?
stratum granulosum
63
Name the layers.
1. Papillary Layer of dermis 2. Reticular Layer of dermis
64
sweat glands whose ducts lead all the way to surface, most numerous on soles of feet, coiled appearance of duct (so cross-section is a circle)
eccrine
65
functions of integumentary system
Protection Sensation Temperature regulation Metabolic Waste elimination
66
Cell Type?
Langerhans cells
67
where is thick skin found?
palms of hands, soles of feet, areas of abrasion
68
Identify.
Meissner corpuscles.
69
Identify.
Pacinian Corpuscles
70
Where are Merkel cells found?
stratum basale
71
epidermis epithelium is...
keratinized stratified squamous
72
Type of tissue in papillary layer? In reticular layer?
aerolar CT dense irregular CT
73
Layer of skin where cells have shrunk a little, are flattened. Has spikey appearance
stratum spinosum
74
Keratohyaline granules stain very...
basophilic

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