Bone and cartilage 1- addition to mind map Flashcards Preview

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Flashcards in Bone and cartilage 1- addition to mind map Deck (12)
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1

What are the 4 types of collagen?

-Type I- most abundant , widely distributed
-Type II- Hyaline and elastic cartilage -fibres thinner than type 1
-Type III- Reticular fibres
-Type IV- Found in the basal lamina. Does not form fibrils

2

What 3 things make up the composition of the basement membrane?

1. glycosaminoglycans (GAGS)
2. Type IV cologne
3.Glycoproteins

3

What is a link protein?

Stabilises the interaction of each proteoglycan with hyaluronan

4

What 3 parts are connective tissue divided into?

1. Soft connective tissue(tendons,ligamnets)
2.Hard connective tissue :bone cartilage
3. Blood and lymph: special form of connective tissue

5

What are the 4 resident cells of connective tissue?

-Fibroblasts
-Adipose cells
-Osteocytes
-chondrocytes

6

What is mesenchyme?

Primitive connective tissue of the embryo

7

Where is the mesoderm derived from?

Mostly the mesoderm , although the neural crest also contributes to mesenchyme in some areas

8

What does mesenchyme consist of?

-stellate or fusiform cells
-some reticular fibres
-ground substance

9

Where is hyaline cartilage found in the body?

-articular surfaces
-tracheal rings
-costal cartilage
-epiphyseal growth plates
-precursor in fetus to many bones

10

Where is elastic cartilage found in the body?

-pinna of the ear
-epiglottis
-auditory tube

11

Where can fibrocartilage be found in the body?

-intervertebral disk
-tendon inserts bone
-punic symphysis

12

How can pathology of cartilage occur?

Chondrocytes from old animals produce shorter proteoglycans than those of young animals. This may lead to lessened ability to attract water molecules and decreased resistance to compression, which in turn may lead to damage of articular cartilages and osteoarthritis.