Bone tumors

Question 1

Bone tumor within the epiphysis with Soap Bubble appearance

Answer 1

Giant Cell tumor

Question 2

Bone tumor with RankL upregulation?

Answer 2

Giant cell tumor

Question 3

Most common benign bone tumor

Answer 3

Osteochondroma

Question 4

Osteochondroma location

Answer 4

Metaphysis with lateral projectile growth

Question 5

Lateral projecctive growth with cartilaginous cap

Answer 5

Osteochondroma

Question 6

Osteocommondroma

Answer 6

Most common benign tumor

Question 7

Found in facial bones

Gardners syndrome

Answer 7

Osteoooma

“Ooom in the garden”

Question 8

Sinus pressure, sinus tumor

Answer 8

Osteoma

Question 9

Painful bone tumor releived by NSAIDs?

Answer 9

Osteoid osteoma

Question 10

Cortical bone tumor with sclerotic margins and radiolucent core
small intralesional nidus?

Answer 10

Osteoid osteoma

Question 11

Small cortical sclerotic margins, radiolucent core, found commonly in the vertebrae

Painful, not releived with NSAID

Answer 11

Osteoblastoma!!

Question 12

Mononuclear Rank-L expressing cells

Answer 12

Giant cell tumor

Question 13

Seen in young teenage males in the metaphysis

Risk factors: Lis Fromani syndrome, Retinoblastoma, Paget disease, Radiation

Answer 13

Osteosarcoma

Question 14

Sunburst appearance on X-ray

Codmanns triangle

Answer 14

Osteosarcoma

Question 15

Tumor occuring in the medulla of the pelvis and central skeleton

Answer 15

Ostochondroma

Question 16

Tumor occuring in children younger than 15 in the diaphysis of long bones

Answer 16

Ewing sarcoma

Question 17

Onion skin appearance on radiographs

Answer 17

Ewing sarcoma

Question 18

Small blue cells resembling lymphocytes that are neuroectodermal?

Answer 18

Ewings Sarcoma

Question 19

Over expression of EWS-FLI1

Answer 19

Seen with T11,22 translocation in Ewings sarcoma

Question 20

Punched out osteolytic lesions

Answer 20

Multiple Myeloma

Question 21

Osteoclasts with numerous nuclei

Answer 21

Giant Cell Tumor!

Question 22

Large diameter nidus > 1.5 cm

Answer 22

Osteoblastomas

Also known for eroding surround bone

Question 23

Small diameter nidus with small surrounding sclerotic bone

Answer 23

Osteoid osteoma

Produce prostoglandins causing pain!

Question 24

Pleomorphic osteoblasts forming toooooo much osteoid tissue in the metaphysis

Answer 24

Osteosarcoma

AKA OsteoStarcoma

Question 25

pRb and p 53 protein malformations

Answer 25

Results in familial retinoblastoma and Lisch Fraumini syndrome Osteosarcoma!

Question 26

Mass within medullary cavity

Answer 26

Chondrosarcoma

Question 27

Moth eaten appearance

Answer 27

Chondrosarcoma